IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2.

Autor: Nikitin PA; Immunome Inc., Exton, PA 19341, USA., DiMuzio JM; Immunome Inc., Exton, PA 19341, USA., Dowling JP; Immunome Inc., Exton, PA 19341, USA., Patel NB; Immunome Inc., Exton, PA 19341, USA., Bingaman-Steele JL; Immunome Inc., Exton, PA 19341, USA., Heimbach BC; Immunome Inc., Exton, PA 19341, USA., Henriquez N; Immunome Inc., Exton, PA 19341, USA., Nicolescu C; Immunome Inc., Exton, PA 19341, USA., Polley A; Immunome Inc., Exton, PA 19341, USA., Sikorski EL; Immunome Inc., Exton, PA 19341, USA., Howanski RJ; Immunome Inc., Exton, PA 19341, USA., Nath M; Immunome Inc., Exton, PA 19341, USA., Shukla H; Immunome Inc., Exton, PA 19341, USA., Scheaffer SM; Departments of Medicine, Molecular Microbiology, Pathology, and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Finn JP; Immunome Inc., Exton, PA 19341, USA., Liang LF; Immunome Inc., Exton, PA 19341, USA., Smith T; Immunome Inc., Exton, PA 19341, USA., Storm N; Department of Microbiology, Boston University School of Medicine and National Emerging Infectious Diseases Laboratories, Boston, MA, USA., McKay LGA; Department of Microbiology, Boston University School of Medicine and National Emerging Infectious Diseases Laboratories, Boston, MA, USA., Johnson RI; Department of Microbiology, Boston University School of Medicine and National Emerging Infectious Diseases Laboratories, Boston, MA, USA., Malsick LE; Department of Microbiology, Boston University School of Medicine and National Emerging Infectious Diseases Laboratories, Boston, MA, USA., Honko AN; Department of Microbiology, Boston University School of Medicine and National Emerging Infectious Diseases Laboratories, Boston, MA, USA., Griffiths A; Department of Microbiology, Boston University School of Medicine and National Emerging Infectious Diseases Laboratories, Boston, MA, USA., Diamond MS; Departments of Medicine, Molecular Microbiology, Pathology, and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Sarma P; Immunome Inc., Exton, PA 19341, USA., Geising DH; Immunome Inc., Exton, PA 19341, USA., Morin MJ; Immunome Inc., Exton, PA 19341, USA., Robinson MK; Immunome Inc., Exton, PA 19341, USA.

Publikováno v: Science immunology [Sci Immunol] 2022 Sep 09; Vol. 7 (75), pp. eabl9943. Date of Electronic Publication: 2022 Sep 09.