Zobrazeno 1 - 10 of 637 pro vyhledávání: '"Geisberger, A."'
1
Akademický článek
Nickel-organo compounds as potential enzyme precursors under simulated early Earth conditions
Autor: Philippe Diederich, Christian Seitz, Lance Buckett, Liesa Salzer, Thomas Geisberger, Wolfgang Eisenreich, Claudia Huber, Philippe Schmitt-Kopplin
Publikováno v: Communications Chemistry, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract The transition from inorganic catalysis through minerals to organic catalysis by enzymes is a necessary step in the emergence of life. Our work is elucidating likely reactions at the earliest moments of Life, prior to the existence of enzyma
Externí odkaz: https://doaj.org/article/62cd18b6ab2844e5a42b04478cf5b063
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2
Akademický článek
Combined DNA Analysis from Stool and Blood Samples Improves Tumor Tracking and Assessment of Clonal Heterogeneity in Localized Rectal Cancer Patients
Autor: Thomas Parigger PhD, Franz Josef Gassner PhD, Stephan Drothler MSc, Christian Scherhäufl MSc, Alexandra Hödlmoser MSc, Lena Schultheis MSc, Aryunni Abu Bakar MSc, Florian Huemer MD, Richard Greil MD, Roland Geisberger PhD, Lukas Weiss MD, PhD, Nadja Zaborsky PhD
Publikováno v: Technology in Cancer Research & Treatment, Vol 23 (2024)
Objectives: In this study, stool samples were evaluated for tumor mutation analysis via a targeted next generation sequencing (NGS) approach in a small patient cohort suffering from localized rectal cancer. Introduction: Colorectal cancer (CRC) cause
Externí odkaz: https://doaj.org/article/9444f640bdc84627b111c7918a84a93d
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3
Akademický článek
C2-addition patterns emerging from acetylene and nickel sulfide in simulated prebiotic hydrothermal conditions
Autor: Philippe Diederich, Alexander Ruf, Thomas Geisberger, Leopold Weidner, Christian Seitz, Wolfgang Eisenreich, Claudia Huber, Philippe Schmitt-Kopplin
Publikováno v: Communications Chemistry, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Chemical complexity is vital not only for the origin of life but also for biological evolution. The chemical evolution of a complex prebiotic mixture containing acetylene, carbon monoxide (CO), and nickel sulfide (NiS) has been analyzed with
Externí odkaz: https://doaj.org/article/feae7688ce404508bee143351e6113ac
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4
Akademický článek
From Zero to Hero: The Cyanide-Free Formation of Amino Acids and Amides from Acetylene, Ammonia and Carbon Monoxide in Aqueous Environments in a Simulated Hadean Scenario.
Autor: Seitz, Christian1 (AUTHOR) c.seitz@tum.de, Geisberger, Thomas1 (AUTHOR), West, Alexander Richard1 (AUTHOR), Fertl, Jessica1 (AUTHOR), Eisenreich, Wolfgang1 (AUTHOR), Huber, Claudia1 (AUTHOR) claudia.huber@tum.de
Publikováno v: Life (2075-1729). Jun2024, Vol. 14 Issue 6, p719. 14p.
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5
Akademický článek
Formation of vesicular structures from fatty acids formed under simulated volcanic hydrothermal conditions
Autor: Thomas Geisberger, Philippe Diederich, Christoph J. O. Kaiser, Kilian Vogele, Alexander Ruf, Christian Seitz, Friedrich Simmel, Wolfgang Eisenreich, Philippe Schmitt-Kopplin, Claudia Huber
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Microscopic compartmentalization is beneficial in synthetic chemistry and indispensable for the evolution of life to separate a reactive “inside” from a hydrolyzing “outside”. Here, we show compartmentalization in aqueous solution co
Externí odkaz: https://doaj.org/article/491e7b4f29154ef2943564ae0772c7ae
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6
Akademický článek
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7
Akademický článek
Validation of genetic variants from NGS data using deep convolutional neural networks
Autor: Marc Vaisband, Maria Schubert, Franz Josef Gassner, Roland Geisberger, Richard Greil, Nadja Zaborsky, Jan Hasenauer
Publikováno v: BMC Bioinformatics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Accurate somatic variant calling from next-generation sequencing data is one most important tasks in personalised cancer therapy. The sophistication of the available technologies is ever-increasing, yet, manual candidate refinement is still
Externí odkaz: https://doaj.org/article/6354773ffd1345a882925ecef572ccef
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8
Akademický článek
From Zero to Hero: The Cyanide-Free Formation of Amino Acids and Amides from Acetylene, Ammonia and Carbon Monoxide in Aqueous Environments in a Simulated Hadean Scenario
Autor: Christian Seitz, Thomas Geisberger, Alexander Richard West, Jessica Fertl, Wolfgang Eisenreich, Claudia Huber
Publikováno v: Life, Vol 14, Iss 6, p 719 (2024)
Amino acids are one of the most important building blocks of life. During the biochemical process of translation, cells sequentially connect amino acids via amide bonds to synthesize proteins, using the genetic information in messenger RNA (mRNA) as
Externí odkaz: https://doaj.org/article/eed61630051f4295abcda17645d5035a
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10
Akademický článek
Formation, stabilization and fate of acetaldehyde and higher aldehydes in an autonomously changing prebiotic system emerging from acetylene
Autor: Philippe Diederich, Thomas Geisberger, Yingfei Yan, Christian Seitz, Alexander Ruf, Claudia Huber, Norbert Hertkorn, Philippe Schmitt-Kopplin
Publikováno v: Communications Chemistry, Vol 6, Iss 1, Pp 1-8 (2023)
Aldehydes can be formed under extraterrestrial conditions, however, the synthesis of aldehydes on early Earth remains largely unclear. Here, the authors report the formation of acetaldehydes and higher condensation products starting from a gaseous mi
Externí odkaz: https://doaj.org/article/169f872f8d714ad183e63aabbddee430
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