Spatial analysis of transcript and protein levels in skeletal muscle.

Autor: Pisterzi P; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., Martinez Mir C; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., Dahri O; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., de Poorter I; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., Batlles Parera S; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., Dostanić M; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., Mastrangeli M; Microelectronics Department, Delft University of Technology, 2628 CD Delft, the Netherlands., Mummery C; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands., Geijsen N; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands. Electronic address: n.geijsen@lumc.nl., Sage F; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 Leiden, the Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, the Netherlands. Electronic address: f.g.sage@lumc.nl.

Publikováno v: STAR protocols [STAR Protoc] 2024 Oct 09; Vol. 5 (4), pp. 103378. Date of Electronic Publication: 2024 Oct 09.

3D Printed Magneto-Active Microfiber Scaffolds for Remote Stimulation and Guided Organization of 3D In Vitro Skeletal Muscle Models.

Autor: Cedillo-Servin G; Department of Orthopaedics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, 3508 GA, The Netherlands.; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, 5612 AE, The Netherlands., Dahri O; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands.; Leiden Node, The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden, 2333 ZA, The Netherlands., Meneses J; Departamento de Engenharia Química, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal.; ALiCE - Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal., van Duijn J; Department of Orthopaedics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, 3508 GA, The Netherlands., Moon H; Department of Orthopaedics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, 3508 GA, The Netherlands., Sage F; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands.; Leiden Node, The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden, 2333 ZA, The Netherlands., Silva J; Departamento de Engenharia Química, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal., Pereira A; Departamento de Engenharia Química, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal., Magalhães FD; Departamento de Engenharia Química, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal.; ALiCE - Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal., Malda J; Department of Orthopaedics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, 3508 GA, The Netherlands.; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3508 GA, The Netherlands., Geijsen N; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands.; Leiden Node, The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden, 2333 ZA, The Netherlands., Pinto AM; Departamento de Engenharia Química, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal.; ALiCE - Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Porto, 4200-465, Portugal., Castilho M; Department of Orthopaedics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, 3508 GA, The Netherlands.; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, 5612 AE, The Netherlands.; Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5612 AE, The Netherlands.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Mar; Vol. 20 (12), pp. e2307178. Date of Electronic Publication: 2023 Nov 10.

Modeling genetic inner ear hearing loss: development of hiPSC-derived inner ear organoids harboring GJB2 mutations.

Autor: van den Boogaard, W. M. C., Vinke, D., Geijsen, N., Shang, P., Locher, H.

Publikováno v: Journal of Hearing Science; Sep2024, Vol. 14 Issue 3, p134-134, 1/2p

The double life of CRISPR–Cas13

Autor: Bot, J.F., Oost, J. van der, Geijsen, N.

Publikováno v: Current Opinion in Biotechnology 78 (2022)
Current Opinion in Biotechnology, 78. CURRENT BIOLOGY LTD
Current Opinion in Biotechnology, 78

Since the discovery of RNA-programmable nucleases from the prokaryotic adaptive immune system CRISPR–Cas, these proteins have seen rapid and widespread adoption for biotechnological and clinical research. A recently discovered system, CRISPR–Cas1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc59501dbbf069eaf5591b32533f1924
https://doi.org/10.1016/j.copbio.2022.102789

High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds.

Autor: Krüger M; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Samsom RA; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Oosterhoff LA; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., van Wolferen ME; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Kooistra HS; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Geijsen N; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., Penning LC; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Kock LM; LifeTec Group BV, Eindhoven, The Netherlands.; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands., Sainz-Arnal P; Laboratory of Organ Bioengineering and Regenerative Medicine, Health Research Institute of Aragon (IIS Aragon), Zaragoza, Spain., Baptista PM; Laboratory of Organ Bioengineering and Regenerative Medicine, Health Research Institute of Aragon (IIS Aragon), Zaragoza, Spain., Spee B; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Oct; Vol. 26 (19), pp. 4949-4958. Date of Electronic Publication: 2022 Aug 26.