Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Geicho, Nakatsu"'
Autor:
Xiaoxuan Xia, William Ka Kei Wu, Sunny Hei Wong, Dabin Liu, Thomas Ngai Yeung Kwong, Geicho Nakatsu, Pearlly S. Yan, Yu-Ming Chuang, Michael Wing-Yan Chan, Olabisi Oluwabukola Coker, Zigui Chen, Yun Kit Yeoh, Liuyang Zhao, Xiansong Wang, Wing Yin Cheng, Matthew Tak Vai Chan, Paul Kay Sheung Chan, Joseph Jao Yiu Sung, Maggie Haitian Wang, Jun Yu
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background Altered microbiome composition and aberrant promoter hypermethylation of tumor suppressor genes (TSGs) are two important hallmarks of colorectal cancer (CRC). Here we performed concurrent 16S rRNA gene sequencing and methyl-CpG bi
Externí odkaz:
https://doaj.org/article/48ee2fc5625d4486a4c1566784db8387
Autor:
Caitlin A. Brennan, Geicho Nakatsu, Carey Ann Gallini Comeau, David A. Drew, Jonathan N. Glickman, Robert E. Schoen, Andrew T. Chan, Wendy S. Garrett
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
There is an increasing understanding of the clinical correlations and potential mechanistic roles of specific members of the gut and tumoral microbiota in colorectal cancer (CRC) initiation, progression, and survival. However, we have yet to parlay t
Externí odkaz:
https://doaj.org/article/350445d2f4bd45cbba8b496430834e5d
Autor:
Zhenwei Dai, Olabisi Oluwabukola Coker, Geicho Nakatsu, William K. K. Wu, Liuyang Zhao, Zigui Chen, Francis K. L. Chan, Karsten Kristiansen, Joseph J. Y. Sung, Sunny Hei Wong, Jun Yu
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Alterations of gut microbiota are associated with colorectal cancer (CRC) in different populations and several bacterial species were found to contribute to the tumorigenesis. The potential use of gut microbes as markers for early
Externí odkaz:
https://doaj.org/article/c900f2f00de04ded9e6840a936db069e
Autor:
Jun Yu, Francis K.L. Chan, Joseph J.Y. Sung, Tetsuo Arakawa, Simon S.M. Ng, Geicho Nakatsu, Wei Kang, Yanquan Zhang, Yujuan Dong, Akira Higashimori
DNA methylation has been identified as a hallmark of gastric cancer (GC). Identifying genes that are repressed by DNA promoter methylation is essential in providing insights into the molecular pathogenesis of gastric cancer. Using genome-wide methyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc23c534cee300696ddede17c2cfe30
https://doi.org/10.1158/0008-5472.c.6510032
https://doi.org/10.1158/0008-5472.c.6510032
Autor:
Naoki Sugimura, Qing Li, Eagle Siu Hong Chu, Harry Cheuk Hay Lau, Winnie Fong, Weixin Liu, Cong Liang, Geicho Nakatsu, Anthony Chin Yang Su, Olabisi Oluwabukola Coker, William Ka Kei Wu, Francis Ka Leung Chan, Jun Yu
Publikováno v:
Gut. 71:2011-2021
ObjectiveUsing faecal shotgun metagenomic sequencing, we identified the depletion ofLactobacillus gallinarumin patients with colorectal cancer (CRC). We aimed to determine the potential antitumourigenic role ofL. gallinarumin colorectal tumourigenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db7b7ab5253b97508223e0c83704cf8f
https://doi.org/10.1136/gutjnl-2020-323951
https://doi.org/10.1136/gutjnl-2020-323951
Autor:
Geicho Nakatsu
Publikováno v:
Journal of Gastroenterology and Hepatology. 37:34-38
The microbiome has revolutionized the field of cancer immunology and checkpoint therapeutics for gastrointestinal malignancies. Combating hepatocellular carcinoma (HCC) by immune checkpoint blockade (ICB) is a unique challenge due in part to chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02403e45aa290acafeb5ae12cf056365
https://doi.org/10.1111/jgh.15715
https://doi.org/10.1111/jgh.15715
Autor:
Tetsuya Tanigawa, Koji Otani, Akira Higashimori, Wataru Suda, Shuhei Hosomi, Toshio Watanabe, Masahira Hattori, Yuji Nadatani, Fumio Tanaka, Yasuaki Nagami, Yasuhiro Fujiwara, Koichi Taira, Shusei Fukunaga, Geicho Nakatsu
Publikováno v:
Gastric Cancer
Background Gastric microbiome, other than Helicobacter pylori, plays a role in the tumorigenesis of gastric cancer (GC). Patients who undergo endoscopic submucosal dissection for early GC have a high risk of developing metachronous GC even after succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e9332996594b9042dcf3a713a7db59
https://doi.org/10.1007/s10120-020-01141-w
https://doi.org/10.1007/s10120-020-01141-w
Autor:
Matthew T. V. Chan, Michael Wing-Yan Chan, Liuyang Zhao, Thomas N.Y. Kwong, Zigui Chen, Jun Yu, Sunny H. Wong, Geicho Nakatsu, Yun Kit Yeoh, Wing Yin Cheng, Maggie Haitian Wang, Dabin Liu, Joseph J.Y. Sung, Xiaoxuan Xia, Paul K.S. Chan, Pearlly S. Yan, William K.K. Wu, Olabisi Oluwabukola Coker, Xiansong Wang, Yu-Ming Chuang
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-13 (2020)
Microbiome
Microbiome
Background Altered microbiome composition and aberrant promoter hypermethylation of tumor suppressor genes (TSGs) are two important hallmarks of colorectal cancer (CRC). Here we performed concurrent 16S rRNA gene sequencing and methyl-CpG binding dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4936e5e6cdfcae80d97420d90fbfb1b3
http://link.springer.com/article/10.1186/s40168-020-00847-4
http://link.springer.com/article/10.1186/s40168-020-00847-4
Autor:
Tong Li, Ying-Xuan Chen, Siew C. Ng, Jing-Yuan Fang, Francis K.L. Chan, Joseph J.Y. Sung, Jessie Qiaoyi Liang, Eagle S. H. Chu, Geicho Nakatsu, Sunny H. Wong, Chun Ho Szeto, Jun Yu, Tung On Yau
Publikováno v:
Gut. 69:1248-1257
ObjectiveThere is a need for early detection of colorectal cancer (CRC) at precancerous-stage adenoma. Here, we identified novel faecal bacterial markers for diagnosing adenoma.DesignThis study included 1012 subjects (274 CRC, 353 adenoma and 385 con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd17be52ccaf0ed5d5f7cf8dc01f2a7
https://doi.org/10.1136/gutjnl-2019-318532
https://doi.org/10.1136/gutjnl-2019-318532
Autor:
Geicho Nakatsu, Jonathan N. Glickman, David A. Drew, Robert E. Schoen, Caitlin A. Brennan, Wendy S. Garrett, Carey Ann Gallini Comeau, Andrew T. Chan
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
There is an increasing understanding of the clinical correlations and potential mechanistic roles of specific members of the gut and tumoral microbiota in colorectal cancer (CRC) initiation, progression, and survival. However, we have yet to parlay t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6f45b536eecf1f444fd882b8b86e79
https://pubmed.ncbi.nlm.nih.gov/33824205
https://pubmed.ncbi.nlm.nih.gov/33824205