Zobrazeno 1 - 10 of 94 pro vyhledávání: '"Gehrand A"'
1
Periodic hypoxia, intermittent pain, and caffeine in male and female neonatal rats: corticosterone, insulin resistance, and hepatic gene expression
Autor: Ashley L. Gehrand, Jonathan M. Phillips, Hershel Raff
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R708-R719
Preterm infants experience multiple stressors including periodic neonatal hypoxia, maternal/caregiver separation, and acute pain from clinical procedures. Although neonatal hypoxia or interventional pain are associated with sexually dimorphic effects
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffbf1142b8a99916f1310eed5142aeea
https://doi.org/10.1152/ajpregu.00316.2022
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3
Akademický článek
The effects of flutamide on the neonatal rat hypothalamic–pituitary–adrenal and gonadal axes in response to hypoxia
Autor: Santiago Rolon, Christine Huynh, Maya Guenther, Minhal Gardezi, Jonathan Phillips, Ashley L. Gehrand, Hershel Raff
Publikováno v: Physiological Reports, Vol 7, Iss 24, Pp n/a-n/a (2019)
Abstract Hypoxia is common with preterm birth and may lead to long‐term effects on the adult hypothalamic–pituitary–adrenal (HPA) axis that are sexually dimorphic due to neonatal androgens. Although the adult rat adrenal does not express apprec
Externí odkaz: https://doaj.org/article/ebfea01220764e978ccad093fb585c3b
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4
Akademický článek
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5
Akademický článek
Effect of Novel Melanocortin Type 2 Receptor (MC2R) Antagonists on the Corticosterone Response to ACTH in the Neonatal Rat Adrenal Gland in vivo and in vitro.
Autor: Nasha K Nensey, Jonathan eBodager, Ashley L Gehrand, Hershel eRaff
Publikováno v: Frontiers in Endocrinology, Vol 7 (2016)
Stress-induced increases in neonatal corticosterone demonstrate a unique shift from ACTH-independence to ACTH-dependence between post-natal day two (PD2) and eight (PD8) in newborn rats. This shift could be due to binding of a bioactive, non-immunore
Externí odkaz: https://doaj.org/article/a449c2ed1bd04970986048637366f529
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6
Glucocorticoid Receptor Antagonist Alters Corticosterone and Receptor-sensitive mRNAs in the Hypoxic Neonatal Rat
Autor: Kyle D Welhouse, Jonathan Phillips, Ashley L. Gehrand, Hana Siddiqui, Hazel Hunt, Matthew Schulgit, Hershel Raff, Jeff Hoffman
Publikováno v: Endocrinology. 163
Hypoxia, a common stressor with preterm birth, increases morbidity and mortality associated with prematurity. Glucocorticoids (GCs) are administered to the preterm infant to improve oxygenation; prolonged use of GCs remains controversial. We evaluate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f1a0a8c2150622524a2ea2e72cd925
https://doi.org/10.1210/endocr/bqab232
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7
Akademický článek
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8
Insulin and glucose responses to hypoxia in male and female neonatal rats: Effects of the androgen receptor antagonist flutamide
Autor: Hershel Raff, Ashley L. Gehrand, Minhal Gardezi, Christine Huynh, Maya Guenther, Santiago Rolon, Jonathan Phillips
Publikováno v: Physiological Reports
Hypoxia is common with preterm birth and may lead to long‐term effects on adult pancreatic endocrine function and insulin sensitivity. This phenomenon may be sexually dimorphic due to the hypoxia‐induced augmentation of the neonatal androgen surg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5755e587a1ce3b849652e5b713235dd7
https://doi.org/10.14814/phy2.14663
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9
Corticosterone, Adrenal, and the Pituitary-Gonadal Axis in Neonatal Rats: Effect of Maternal Separation and Hypoxia
Autor: Kevin Malott, Jonathan Phillips, Ashley L. Gehrand, Hershel Raff
Publikováno v: Endocrinology
Hypoxia, a common stressor in prematurity, leads to sexually dimorphic, short- and long-term effects on the adult hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes. We hypothesized that these effects are due to stress
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2782891e626271176371401b50606e8
https://europepmc.org/articles/PMC7310600/
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10
SUN-214 A Novel Glucocorticoid Receptor Antagonist (CORT113176) Reveals Unique Developmental and Tissue-Specific Effects in a Neonatal Rat Model of Human Prematurity
Autor: Jonathan Phillips, Hershel Raff, Hana Siddiqui, Kyle D Welhouse, Ashley L. Gehrand, Matthew Schulgit
Publikováno v: Journal of the Endocrine Society
Premature birth is a major public health problem worldwide and can lead to transient adrenal insufficiency1,2. The stress of premature birth includes the inability to control blood glucose and maintain normal oxygenation leading to hypoxia3. Corticos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b796bc032741ed873750095b00c6848
http://europepmc.org/articles/PMC7208664
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