Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Gehan M. Kamel"'
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 42:452-460
Values for pharmacokinetic variables are usually obtained in healthy animals, whereas drugs are frequently administered to diseased animals. This study investigated cefquinome pharmacokinetics in healthy goats and goats with experimentally induced ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc6529644b1cff40ea0aafa69445256
https://doi.org/10.1111/jvp.12790
https://doi.org/10.1111/jvp.12790
Autor:
Mona M. E. Eleiwa, Gehan M. Kamel, Yasmina M. Abd El-Hakim, Ali Gab-Alllah, M.M. Hashem, Khaled Abo-EL-Sooud
Publikováno v:
International Journal of Pharmacy and Pharmaceutical Sciences. :28-31
Objective: Daily exposure to food preservatives constitutes a major crisis to children especially during vaccination so; the aim of the study is to assess the effect of sodium nitrite on the immune responses against Rift Valley fever vaccine (RVFV) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e6300cd36506293b611a8b6b0ac4038
https://doi.org/10.22159/ijpps.2019v11i7.33443
https://doi.org/10.22159/ijpps.2019v11i7.33443
Publikováno v:
Bioorganic chemistry. 100
In this study, new pyrazolopyrimidine derivatives were designed and evaluated for anticancer activity. PIM-1 inhibitiory activity were measured for the most potent compounds. Molecular docking study and molecular dynamics were also done. Thus, the no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd4077b9453f62ac897038156914bfc
https://pubmed.ncbi.nlm.nih.gov/32450389
https://pubmed.ncbi.nlm.nih.gov/32450389
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss, Pp 112456-(2022)
Ivy leaves (Hedera helix) is a traditional plant used for common cold, cough, and bronchial disorders and can be used for rheumatoid arthritis (RA) as an attempt in alternative medicine. RA is a chronic autoimmune disease characterized by its increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75c31c965f675a9344b72306ab2c336
https://doi.org/10.1016/j.biopha.2021.112456
https://doi.org/10.1016/j.biopha.2021.112456
Publikováno v:
Journal of Applied Veterinary Sciences, Vol 3, Iss 1, Pp 26-33 (2018)
The aim of present study was to investigate the phytochemical screening, acute toxicity and some pharmacological activities of ethanolic extract 70 % and 99.9% of apricot seeds. The phytochemical screening was done for determination of total phenolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1410f5fd38cf914af5c6fb352f50030b
https://doi.org/10.21608/javs.2018.62723
https://doi.org/10.21608/javs.2018.62723
Autor:
Yaseen A.M.M. Elshaier, Wael A.A. Fadaly, Khaled R.A. Abdellatif, Waleed A.M. Ali, Gehan M. Kamel
Publikováno v:
Bioorganic Chemistry. 77:568-578
Twelve new compounds of 1,3,4-trisubstituted-pyrazole derivatives possessing two cyclooxygenase-2 (COX-2) pharmacophoric moieties (SO2Me or/and SO2NH2) 11a-c, 12a-c, 13a-c and 14a-c were designed and synthesized to be evaluated for their COX inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefe92530f33c6b920f80124351fd354
https://doi.org/10.1016/j.bioorg.2018.02.018
https://doi.org/10.1016/j.bioorg.2018.02.018
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 31:54-60
A new series of 1,5-diarylpyrazoles 10a–l was designed and synthesized for evaluation as COX inhibitors and as anti-inflammatory agents. All compounds were more selective for COX-2 isozyme and showed good in vivo anti-inflammatory activity. Compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69496eda3db9c5019e3cfa6064ff0bd
https://doi.org/10.1080/14756366.2016.1201815
https://doi.org/10.1080/14756366.2016.1201815
Autor:
Eman K. A. Abdelall, Gehan M. Kamel
Publikováno v:
European Journal of Medicinal Chemistry. 118:250-258
Two new series of 1,5-diaryl pyrazoles (5a, 5b, 7a, 7b and 10) and 1,5-diaryl pyrazoline (12a and 12b) were prepared as both Cyclooxygenase-2 and 15-lipoxygenase inhibitors. Carrageenan-induced rat paw edema, ulcer index and anti-COX-1/COX-2 and 15-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7c2a9303a9c45bdb188efcda40441d
https://doi.org/10.1016/j.ejmech.2016.04.049
https://doi.org/10.1016/j.ejmech.2016.04.049
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:406-412
Two new series of 1,3,5-triarylpyrazolines 10a–m and 1,5-diarylpyrazoles 14a–d were synthesized. All prepared compounds were evaluated for their in vitro COX-1/COX-2 inhibitory activity and the in vivo anti-inflammatory activity. All compounds we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef87716b7f4f4e554aa2857c8f224289
https://doi.org/10.1016/j.bmcl.2015.11.105
https://doi.org/10.1016/j.bmcl.2015.11.105
Autor:
Yasmina M. Abd El-Hakim, A. Q. Gab-Allaha, Gehan M. Kamel, Khaled Abo-EL-Sooud, Mohamed Hashem
Publikováno v:
International immunopharmacology. 62
The present study was planned to examine the effect of butylated hydroxy toluene (BHT) on the immune response of Rift Valley fever vaccine (RVFV) in Swiss mice. Animals were divided into four equal groups. The first group was kept as negative control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309d727700012217c2717f1c87b16ee6
https://pubmed.ncbi.nlm.nih.gov/30015236
https://pubmed.ncbi.nlm.nih.gov/30015236