Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gege Tan"'
Autor:
Jing Hua, Ricard Masia, Simon Turcotte, John Stagg, Jonathan Hill, Matthew Rausch, Devapregasan Moodley, Marisa Peluso, Secil Koseoglu, Gege Tan, Benjamin Lee, Isabelle Cousineau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/c0e1d5b32e4a47598c694efc312fdced
Autor:
Andreas Varkaris, Erika Hamilton, Jason Henry, Alexander I. Spira, Alison M. Schram, Julia E. McGuinness, Gege Tan, Xiaoyan Li, Tamieka Hunter, Ramin Samadani, Alison Timm, Djuro Karanovic, Vivek Subbiah, Cesar A. Perez
Publikováno v:
Cancer Research. 83:OT3-22
Background: Targeting constitutively active mutant kinases with selective small molecule inhibitors is a key therapeutic pillar of precision oncology. Phosphatidylinositol-4,5bisphosphate-3 kinase, catalytic subunit alpha (PIK3CA) mutations leading t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8331362fa97029b0aff2e112d4d683
https://doi.org/10.1158/1538-7445.sabcs22-ot3-22-01
https://doi.org/10.1158/1538-7445.sabcs22-ot3-22-01
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Methods, Figures S1-S11, and Table Legends. Supplementary Methods: description of methods used in the Supplementary figures, expanded description of ELISA assays, and description of the computational model of multiple EGFR ligand antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0589dd9379473a98d20e9845ac6751
https://doi.org/10.1158/1535-7163.22501833.v1
https://doi.org/10.1158/1535-7163.22501833.v1
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Tables S2, S3, S4. Structure of the computational model of multiple ligand antagonists: species (Table S2), parameters (Table S3), and Reactions (Table S4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c534d560032452e0b5101eea8d16d10b
https://doi.org/10.1158/1535-7163.22501827
https://doi.org/10.1158/1535-7163.22501827
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Table S1. Cell lines and cell culture conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0501a563d004db70756494b7092751e4
https://doi.org/10.1158/1535-7163.22501830
https://doi.org/10.1158/1535-7163.22501830
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Tables S5, S6, S7, S8. mRNA expression data for EGFR ligands as measured by RNAseq from The Cancer Genome Atlas (TCGA) across 14 cancer indications or by RT-qPCR of colorectal cancer FFPE samples. Table S5: Summary of TCGA datasets incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5782fe1fa8c256671852ceadb513a3f4
https://doi.org/10.1158/1535-7163.22501824
https://doi.org/10.1158/1535-7163.22501824
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Purpose: Insulin-like growth factor receptor 1 (IGF-1R) is critically involved in pancreatic cancer pathophysiology, promoting cancer cell survival and therapeutic resistance. Assessment of IGF-1R inhibitors in combination with standard-of-care chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67565d75c08617bb5e48fee4d51b15c3
https://doi.org/10.1158/1078-0432.c.6526055.v1
https://doi.org/10.1158/1078-0432.c.6526055.v1
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Supplemental Figure S1: IGF-1 and HRG induce strongest AKT phosphorylation in pancreatic cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e60819117dd02fcb2502c593cb58ab3
https://doi.org/10.1158/1078-0432.22465559.v1
https://doi.org/10.1158/1078-0432.22465559.v1
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f42cbe77298eae397c79869e3f6871f
https://doi.org/10.1158/1078-0432.22465535.v1
https://doi.org/10.1158/1078-0432.22465535.v1
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f3bcbb0f2da6bc498d87084abe5f06
https://doi.org/10.1158/1078-0432.22465538.v1
https://doi.org/10.1158/1078-0432.22465538.v1