Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Geetha S. Hewawasam"'
Autor:
Karthik Dhatchinamoorthy, Geetha S. Hewawasam, Chris Seidel, Mark Mattingly, Jennifer L. Gerton
Publikováno v:
Nucleic Acids Research
Correct localization of the centromeric histone variant CenH3/CENP-A/Cse4 is an important part of faithful chromosome segregation. Mislocalization of CenH3 could affect chromosome segregation, DNA replication and transcription. CENP-A is often overex
Autor:
Jennifer L. Gerton, Jerry L. Workman, Mark Mattingly, Swaminathan Venkatesh, Laurence Florens, Geetha S. Hewawasam, Ying Zhang
Publikováno v:
The Journal of Biological Chemistry
Background: Psh1 is an E3 ubiquitin ligase that controls CenH3/Cse4 levels through proteolysis in budding yeast. Results: Psh1 is phosphorylated in vivo by CK2, and its E3 ligase activity is promoted. Conclusion: Phosphorylation is crucial in Psh1-as
Autor:
Ben-Jiang Ma, Eden P. Go, Geetha S. Hewawasam, Hua-Xin Liao, Heather Desaire, Barton F. Haynes
Publikováno v:
International journal of mass spectrometry. 305(2-3)
The work presented herein describes the first comprehensive analysis of a partially deglycosylated HIV vaccine candidate envelope protein (Env). The Env, JRFL gp140 ΔCF, with 27 potential glycosylation sites, was partially deglycosylated with PNGase
Autor:
David Hua, Li Hua Ping, Eden P. Go, Heather Desaire, Hua-Xin Liao, Haiyan Chen, Jeffrey A. Anderson, Geetha S. Hewawasam, Barton F. Haynes
The analysis of HIV-1 envelope carbohydrates is critical to understanding their roles in HIV-1 transmission as well as in binding of envelope to HIV-1 antibodies. However, direct analysis of protein glycosylation by glycopeptide-based mass mapping ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d295da5d7be6c9b5a14795f564ac8e
https://europepmc.org/articles/PMC3147976/
https://europepmc.org/articles/PMC3147976/
Publikováno v:
Cell cycle (Georgetown, Tex.). 10(4)
566 Cell Cycle Volume 10 Issue 4 Chromosome segregation is a key step to ensure the genetic material is equally distributed between the two daughter cells during cell division. Accuracy of this process is ensured by microtubule attachment to properly
Autor:
Laurence Florens, Jerry L. Workman, Skylar Martin-Brown, Manjunatha Shivaraju, Geetha S. Hewawasam, Jennifer L. Gerton, Mark Mattingly, Swaminathan Venkatesh
Cse4 is a variant of histone H3 that is incorporated into a single nucleosome at each centromere in budding yeast. We have discovered an E3 ubiquitin ligase, called Psh1, which controls the cellular level of Cse4 via ubiquitylation and proteolysis. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9640b3e4aa8124d3aeb1f2294edf45e
https://europepmc.org/articles/PMC2998187/
https://europepmc.org/articles/PMC2998187/