Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Geetha Chalasani"'
Autor:
Kevin Louis, Elodie Bailly, Camila Macedo, Louis Lau, Bala Ramaswami, Alexander Chang, Uma Chandran, Douglas Landsittel, Xinyan Gu, Geetha Chalasani, Adriana Zeevi, Parmjeet Randhawa, Harinder Singh, Carmen Lefaucheur, Diana Metes
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Alloimmune responses driven by donor-specific antibodies (DSAs) can lead to antibody-mediated rejection (ABMR) in organ transplantation. Yet, the cellular states underlying alloreactive B cell responses and the molecular components controlling them r
Externí odkaz:
https://doaj.org/article/6e3a7b3fbce24424adc7139960536e1c
Autor:
Lisa B Boyette, Camila Macedo, Kevin Hadi, Beth D Elinoff, John T Walters, Bala Ramaswami, Geetha Chalasani, Juan M Taboas, Fadi G Lakkis, Diana M Metes
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176460 (2017)
Human monocytes have been grouped into classical (CD14++CD16-), non-classical (CD14dimCD16++), and intermediate (CD14++CD16+) subsets. Documentation of normal function and variation in this complement of subtypes, particularly their differentiation p
Externí odkaz:
https://doaj.org/article/863313e898534c5fb70bd02d9b48d1f4
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36138 (2012)
Mycoplasmas cause numerous human diseases and are common opportunistic pathogens in cancer patients and immunocompromised individuals. Mycoplasma infection elicits various host immune responses. Here we demonstrate that mycoplasma-infected tumor cell
Externí odkaz:
https://doaj.org/article/704962e8d9444f72af3f672e06071603
Publikováno v:
Aging and Disease
Plasmacytoid dendritic cells (pDC), a highly specialized class of innate immune cells that serve as rapid sensors of danger signals in circulation or in lymphoid tissue are well studied. However, there remains knowledge gaps about age-dependent chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351471a6b69fe604e33d8d8788b96fd5
http://europepmc.org/articles/PMC8279532
http://europepmc.org/articles/PMC8279532
Autor:
Marilyn Marrari, Bala Ramaswami, Douglas Landsittel, Diana Metes, Fadi G. Lakkis, Beth Elinoff, Geetha Chalasani, John T. Walters, A. R. Shields, Camila Macedo, Rita R. Alloway, E. Steve Woodle, Kevin Hadi, Adriana Zeevi
Publikováno v:
Kidney International Reports
Introduction The cellular events that contribute to generation of donor-specific anti-HLA antibodies (DSA) post-kidney transplantation (KTx) are not well understood. Characterization of such mechanisms could allow tailoring of immunosuppression to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04f6a659a0d1bcae226c40ac8a8622b
http://europepmc.org/articles/PMC6409398
http://europepmc.org/articles/PMC6409398
Autor:
Bala Ramaswami, Harinder Singh, Douglas Landsittel, Xinyan Gu, Kevin Louis, Carmen Lefaucheur, Elodie Bailly, Alexander Chang, Geetha Chalasani, Camila Macedo, Adriana Zeevi, Diana Metes, Louis H. S. Lau, Parmjeet Randhawa, Uma R. Chandran
Publikováno v:
JCI Insight
Alloimmune responses driven by donor-specific antibodies (DSAs) can lead to antibody-mediated rejection (ABMR) in organ transplantation. Yet, the cellular states underlying alloreactive B cell responses and the molecular components controlling them r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6246e4dc866dee01408eedab3de4f4c1
https://pubmed.ncbi.nlm.nih.gov/34032636
https://pubmed.ncbi.nlm.nih.gov/34032636
Autor:
Marilyn Marrari, Carmen Lefaucheur, Uma R. Chandran, Louis H. S. Lau, Diana Metes, Parmjeet Randhawa, Bala Ramaswami, Adriana Zeevi, Alexander Chang, Camila Macedo, Kevin Louis, Elodie Bailly, Paul Fadakar, Douglas Landsittel, Harinder Singh, Masaki Yamada, Geetha Chalasani
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Although antibody-mediated rejection (ABMR) has been long recognized as a leading cause of allograft failure after kidney transplantation, the cellular and molecular processes underlying the induction of deleterious donor-specific antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308344ed618065ce55916baa76919206
https://europepmc.org/articles/PMC7608995/
https://europepmc.org/articles/PMC7608995/
Autor:
Jared M. Pollard, Geetha Chalasani, Stella H. Khiew, Dharmendra Jain, James S. Young, Dong-Kha V. Tran, Maria-Luisa Alegre, Anita S. Chong, Michael S. Andrade, Dengping Yin, Ashley Suah
Publikováno v:
J Clin Invest
Immunological tolerance to semiallogeneic fetuses is necessary to achieving successful first pregnancy and permitting subsequent pregnancies with the same father. Paradoxically, pregnancy is an important cause of sensitization, resulting in the accel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbc85c0483598ca7441a7d2ddab4af0
https://pubmed.ncbi.nlm.nih.gov/34291763
https://pubmed.ncbi.nlm.nih.gov/34291763
Publikováno v:
Clinical Journal of the American Society of Nephrology. 11:137-154
B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies that contribute to tissue injury via multiple mechanisms. In addition, B cells contribute to disease pathogenesis in au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15caf030ee6c9d812cf4813e60611b32
https://doi.org/10.2215/cjn.09430915
https://doi.org/10.2215/cjn.09430915
Autor:
Salwa Zahalka, Geetha Chalasani, R. Ippolito, Parmjeet Randhawa, Yue-Harn Ng, Qi Li, Qiang Zeng, Ke Jiang, Frances E. Lund, Rosemary A. Hoffman, Khaleefathullah A. Sheriff, B. Ramaswami, Tripti Singh
Publikováno v:
Journal of Clinical Investigation. 124:1052-1056
Chronic rejection is the primary cause of long-term failure of transplanted organs and is often viewed as an antibody-dependent process. Chronic rejection, however, is also observed in mice and humans with no detectable circulating alloantibodies, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf2a7d27f2b9cc47b6c7c678239d319
https://doi.org/10.1172/jci70084
https://doi.org/10.1172/jci70084