Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Geetha Balarajah"'
Autor:
Nada M S Al-Saffar, Alice Agliano, Lynley V Marshall, L Elizabeth Jackson, Geetha Balarajah, Jasmin Sidhu, Paul A Clarke, Chris Jones, Paul Workman, Andrew D J Pearson, Martin O Leach
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180263 (2017)
Recent experimental data showed that the PI3K pathway contributes to resistance to temozolomide (TMZ) in paediatric glioblastoma and that this effect is reversed by combination treatment of TMZ with a PI3K inhibitor. Our aim is to assess whether this
Externí odkaz:
https://doaj.org/article/cb11a1ee5827424e87467afe500fd721
Autor:
Nada M S Al-Saffar, Lynley V Marshall, L Elizabeth Jackson, Geetha Balarajah, Thomas R Eykyn, Alice Agliano, Paul A Clarke, Chris Jones, Paul Workman, Andrew D J Pearson, Martin O Leach
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103835 (2014)
The phosphoinositide 3-kinase (PI3K) pathway is believed to be of key importance in pediatric glioblastoma. Novel inhibitors of the PI3K pathway are being developed and are entering clinical trials. Our aim is to identify potential non-invasive bioma
Externí odkaz:
https://doaj.org/article/b991f104a5e54c54aa0a699f5b8655f0
Autor:
Robert H. Jones, Raghav Sundar, Udai Banerji, Richard H. Wilson, J.C. Dawes, Matthew G Krebs, Flavia M. de Oliveira, Suzanne Carreira, Bristi Basu, James Spicer, Mona Parmar, Holly Tovey, Nicola Steele, Karen E Swales, Johann S. de Bono, Michael Brada, Geetha Balarajah, Emma Hall, Denis Talbot
Publikováno v:
Journal of Clinical Oncology. 35:2571-2571
2571 Background: In ovarian cells isolated from ascites, p-S6K levels were found to correlate with resistance to chemotherapy. We hypothesised that inhibiting p-S6K signalling with dual m-TORC1/2 inhibitor vistusertib (V) in addition to paclitaxel (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99ea26f6482bad62f13d3afa917b154
https://doi.org/10.1200/jco.2017.35.15_suppl.2571
https://doi.org/10.1200/jco.2017.35.15_suppl.2571
Autor:
Lynley V. Marshall, Thomas R. Eykyn, Martin O. Leach, Alice Agliano, Geetha Balarajah, Chris Jones, Paul A. Clarke, L. Elizabeth Jackson, Nada M.S. Al-Saffar, Paul Workman, Andrew D.J. Pearson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e103835 (2014)
PLoS ONE, Vol 9, Iss 8, p e103835 (2014)
The phosphoinositide 3-kinase (PI3K) pathway is believed to be of key importance in pediatric glioblastoma. Novel inhibitors of the PI3K pathway are being developed and are entering clinical trials. Our aim is to identify potential non-invasive bioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acd4dc80b3b8dbfe3295eff3a406c53
https://pubmed.ncbi.nlm.nih.gov/25084455
https://pubmed.ncbi.nlm.nih.gov/25084455
Publikováno v:
Gastroenterology. 134:A-196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa704a2e2cdf5e40012a496121437100
https://doi.org/10.1016/s0016-5085(08)60905-1
https://doi.org/10.1016/s0016-5085(08)60905-1