Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Geetha, Kannan"'
Autor:
Fengrong Wang, Michael J. Holmes, Hea Jin Hong, Pariyamon Thaprawat, Geetha Kannan, My-Hang Huynh, Tracey L. Schultz, M. Haley Licon, Sebastian Lourido, Wenzhao Dong, Jailson Brito Querido, William J. Sullivan, Seán E. O’Leary, Vern B. Carruthers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The parasite Toxoplasma gondii persists in its hosts by converting from replicating tachyzoites to latent bradyzoites housed in tissue cysts. The molecular mechanisms that mediate T. gondii differentiation remain poorly understood. Through a
Externí odkaz:
https://doaj.org/article/344823925b104d6a82ccf0c94f14d18f
Autor:
David Smith, Geetha Kannan, Isabelle Coppens, Fengrong Wang, Hoa Mai Nguyen, Aude Cerutti, Einar B Olafsson, Patrick A Rimple, Tracey L Schultz, Nayanna M Mercado Soto, Manlio Di Cristina, Sébastien Besteiro, Vern B Carruthers
Publikováno v:
eLife, Vol 10 (2021)
Many of the world’s warm-blooded species are chronically infected with Toxoplasma gondii tissue cysts, including an estimated one-third of the global human population. The cellular processes that permit long-term persistence within the cyst are lar
Externí odkaz:
https://doaj.org/article/7e32e96532dc4bf1a8c6d709d75c0a60
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Chronic infection of humans with Toxoplasma gondiiT. gondii
Externí odkaz:
https://doaj.org/article/069d182b8a5d4ee195a8f2a4de651223
Autor:
Christian McDonald, David Smith, Manlio Di Cristina, Geetha Kannan, Zhicheng Dou, Vern B. Carruthers
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT The lysosome-like vacuolar compartment (VAC) is a major site of proteolysis in the intracellular parasite Toxoplasma gondii. Previous studies have shown that genetic ablation of a VAC-residing cysteine protease, cathepsin protease L (CPL), r
Externí odkaz:
https://doaj.org/article/f28ca7b56c8f483ca29aa45225b73bdc
Autor:
Geetha Kannan, Manlio Di Cristina, Aric J. Schultz, My-Hang Huynh, Fengrong Wang, Tracey L. Schultz, Matteo Lunghi, Isabelle Coppens, Vern B. Carruthers
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Toxoplasma gondii is a ubiquitous pathogen that can cause encephalitis, congenital defects, and ocular disease. T. gondii has also been implicated as a risk factor for mental illness in humans. The parasite persists in the brain as slow-grow
Externí odkaz:
https://doaj.org/article/ae12df682df347df9a095dba059bb18f
Autor:
Geetha Kannan, Joshua A. Crawford, ChunXia Yang, Kristin L. Gressitt, Chinezimuzo Ihenatu, Irina N. Krasnova, Jean Lud Cadet, Robert H. Yolken, Emily G. Severance, Mikhail V. Pletnikov
Publikováno v:
Neurobiology of Disease, Vol 91, Iss , Pp 307-314 (2016)
Background: Toxoplasma gondii is a pathogen implicated in psychiatric disorders. As elevated antibodies to T. gondii are also present in non-symptomatic individuals, we hypothesized that the age during first exposure to the pathogen may affect sympto
Externí odkaz:
https://doaj.org/article/e36d09c1dd724bf4830a5bd54136483a
Publikováno v:
Scientifica, Vol 2018 (2018)
Infection with the protozoan parasite, Toxoplasma gondii (T. gondii), was linked to several psychiatric disorders. The exact mechanisms of a hypothesized contribution of T. gondii infection are poorly understood, and it appears that only a subset of
Externí odkaz:
https://doaj.org/article/acead8d955ba48c7aebabead5eaf4f49
Publikováno v:
Neurobiology of Disease, Vol 57, Iss , Pp 5-11 (2013)
Gene–environment interactions (GEIs) likely play significant roles in the pathogenesis of schizophrenia and underlie differences in pathological, behavioral, and clinical presentations of the disease. Findings from epidemiology and psychiatric gene
Externí odkaz:
https://doaj.org/article/32448a3a81344c6a93f88d469da38ff9
Autor:
Jianchun Xiao, Ye Li, Emese Prandovszky, Geetha Kannan, Raphael P Viscidi, Mikhail V Pletnikov, Robert H Yolken
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004674 (2016)
There is marked variation in the human response to Toxoplasma gondii infection. Epidemiological studies indicate associations between strain virulence and severity of toxoplasmosis. Animal studies on the pathogenic effect of chronic infection focused
Externí odkaz:
https://doaj.org/article/17d96bc7f64d4500888a594be362d75f
Autor:
K. Thirumavalavan, Ramachandran Subramanian, Rusal Raj Francis, Aisha Abdul Raouf, Geetha Kannan, Suresh Gupta, B.G. Prakash Kumar
Publikováno v:
Materials Today: Proceedings. 28:852-855
Torrefied materials produced from agricultural waste is regarded as one of the most efficient renewable energy source. By recycling the waste materials through optimized torrefaction process, coal like material can be produced. The raw materials are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927a3e350bd57573e45b5104c3e97330
https://doi.org/10.1016/j.matpr.2019.12.311
https://doi.org/10.1016/j.matpr.2019.12.311