Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Geetha, Banda"'
Autor:
Yaoyu Ning, Chester A. Metcalf, Lois Commodore, Jan Romero, Scott Wardwell, Tomi K. Sawyer, Yihan Wang, Qurish K. Mohemmad, Scott Paul Lentini, Ingrid Chen, Victor M. Rivera, Karin Russian, Geetha Banda, Sasmita Das, Narayana I. Narasimhan, Xiaotian Zhu, Raji Sundaramoorthi, Lisi Cai, Tianjun Zhou, Jeff Keats, Frank Wang, Tim Clackson, Qihong Xu, Jiwei Qi, David Wen, Joseph Snodgrass, Shuangying Liu, William C. Shakespeare, R. Mathew Thomas, Marc I Broudy, John Iuliucci, Wei-Sheng Huang, David C. Dalgarno, Dong Zou
Publikováno v:
Journal of Medicinal Chemistry. 53:4701-4719
In the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors, the T315I gatekeeper mutant has emerged as resistant to all currently approved agents. This report describes the structure-guided design of a novel series of potent pa
Autor:
Jeff Keats, Marc I Broudy, John Iuliucci, Scott Wardwell, Karin Russian, Sasmita Das, Yaoyu Ning, Scott Paul Lentini, Yihan Wang, David Wen, William C. Shakespeare, Joseph Snodgrass, Tomi K. Sawyer, David C. Dalgarno, R. Mathew Thomas, Xiaotian Zhu, Mohammad Azam, Shuangying Liu, George Q. Daley, Wei-Sheng Huang, Raji Sundaramoorthi, Tim Clackson, Geetha Banda, Qihong Xu, Frank Wang
Publikováno v:
Journal of Medicinal Chemistry. 52:4743-4756
A novel series of potent dual Src/Abl kinase inhibitors based on a 9-(arenethenyl)purine core has been identified. Unlike traditional dual Src/Abl inhibitors targeting the active enzyme conformation, these inhibitors bind to the inactive, DFG-out con
Autor:
Tomi K. Sawyer, Sasmita Das, Yihan Wang, R. Mathew Thomas, David Wen, Scott Paul Lentini, William C. Shakespeare, Wei-Sheng Huang, Raji Sundaramoorthi, Shuangying Liu, Geetha Banda
Publikováno v:
Tetrahedron Letters. 48:7388-7391
The first example of a Heck reaction with 9-vinylpurines and aryl halides is described. It gives exclusively E -9-(arenethenyl)purines in high yields. Subsequent hydrogenation furnishes 9-(arenethyl)purines quantitatively.
Autor:
I. E. Chakravarthy, Geetha Banda
Publikováno v:
Tetrahedron: Asymmetry. 17:1684-1687
A new and convergent synthetic route for (5 RS )-Hagen’s lactones 1 – 4 is described, starting from bisacetonide mannofuranolactone 5 . The key transformations in the synthesis are SmI 2 mediated α-deoxygenation of a aldonolactone to 2-deoxy lac
Publikováno v:
ChemInform. 37
Autor:
Wei-Sheng Huang, Chester A. Metcalf, Raji Sundaramoorthi, Yihan Wang, Dong Zou, R. Mathew Thomas, Xiaotian Zhu, Lisi Cai, David Wen, Shuangying Liu, Jan Romero, Jiwei Qi, Ingrid Chen, Geetha Banda, Scott P. Lentini, Sasmita Das, Qihong Xu, Jeff Keats, Frank Wang, Scott Wardwell
Publikováno v:
Journal of Medicinal Chemistry; Jun2010, Vol. 53 Issue 12, p4701-4719, 19p
Autor:
Wei-Sheng Huang, Xiaotian Zhu, Yihan Wang, Mohammad Azam, David Wen, Raji Sundaramoorthi, R. Mathew Thomas, Shuangying Liu, Geetha Banda, Scott P. Lentini, Sasmita Das, Qihong Xu, Jeff Keats, Frank Wang, Scott Wardwell, Yaoyu Ning, Joseph T. Snodgrass, Marc I. Broudy, Karin Russian, George Q. Daley
Publikováno v:
Journal of Medicinal Chemistry; Aug2009, Vol. 52 Issue 15, p4743-4756, 14p
Autor:
Choudhury, Amitava, Geetha, Banda, Sangeetha, Nimma Rajaiah, Kavita, Vanaparthi, Susila, Vishnubhatla, Pal, Samudranil
Publikováno v:
Journal of Coordination Chemistry; Jul1999, Vol. 48 Issue 1, p87-95, 9p