Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Geertruij Te Kronnie"'
Autor:
Alessia Buratin, Bruno Palhais, Enrico Gaffo, Juliette Roels, Julie Morscio, Jolien Van Laere, Silvia Orsi, Geertruij te Kronnie, Pieter Van Vlierberghe, Panagiotis Ntziachristos, Stefania Bortoluzzi
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/43b912749bb04884b7c1d3dde615d00b
Autor:
Alessia Buratin, Cristina Borin, Caterina Tretti Parenzan, Anna Dal Molin, Silvia Orsi, Andrea Binatti, Katharina Simon, Maddalena Paganin, Valentina Serafin, Enrico Gaffo, Geertruij te Kronnie, Pieter Van Vlierberghe, Silvia Bresolin, Stefania Bortoluzzi
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-6 (2023)
Abstract Circular RNAs (circRNAs) are emerging as new players in leukemogenic mechanisms. In patients with T-cell Acute Lymphoblastic Leukemia (T-ALL), the recent report of a remarkable dysregulation of circRNAs incited further functional investigati
Externí odkaz:
https://doaj.org/article/4e80c49338d34ee9979460e114508294
Autor:
Grazia Fazio, Silvia Bresolin, Daniela Silvestri, Manuel Quadri, Claudia Saitta, Elena Vendramini, Barbara Buldini, Chiara Palmi, Michela Bardini, Andrea Grioni, Silvia Rigamonti, Marta Galbiati, Stefano Mecca, Angela Maria Savino, Alberto Peloso, Jia-Wey Tu, Sanil Bhatia, Arndt Borkhardt, Concetta Micalizzi, Luca Lo Nigro, Franco Locatelli, Valentino Conter, Carmelo Rizzari, Maria Grazia Valsecchi, Geertruij te Kronnie, Andrea Biondi, Giovanni Cazzaniga
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104224- (2022)
Summary: Background: Despite intensive risk-based treatment protocols, 15% of paediatric patients with B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL) experience relapse. There is urgent need of novel strategies to target poor prognosis subg
Externí odkaz:
https://doaj.org/article/17f5ee578ac94300bf285fbf5e61cf13
Autor:
Anna Dal Molin, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Hélène Cavé, Christian Flotho, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, Jan Philippé, Barbara De Moerloose, Geertruij te Kronnie, Silvia Bresolin, Tim Lammens, Stefania Bortoluzzi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Juvenile myelomonocytic leukemia (JMML), a rare myelodysplastic/myeloproliferative neoplasm of early childhood, is characterized by clonal growth of RAS signaling addicted stem cells. JMML subtypes are defined by specific RAS pathway mutations and di
Externí odkaz:
https://doaj.org/article/ef46116954d54794987bb5e59f8888b4
Autor:
Anna Dal Molin, Silvia Bresolin, Enrico Gaffo, Caterina Tretti, Elena Boldrin, Lueder H. Meyer, Paola Guglielmelli, Alessandro M. Vannucchi, Geertruij te Kronnie, Stefania Bortoluzzi
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Chromosomal translocations harbored by cancer genomes are important oncogenic drivers. In MLL rearranged acute leukemia (MLLre) MLL/KMT2A fuses with over 90 partner genes. Mechanistic studies provided clues of MLL fusion protein leukemogenic potentia
Externí odkaz:
https://doaj.org/article/05caee49360f48869721a610e709119e
Autor:
Anna Dal Molin, Caterina Tretti Parenzan, Enrico Gaffo, Cristina Borin, Elena Boldrin, Lueder H Meyer, Geertruij te Kronnie, Silvia Bresolin, Stefania Bortoluzzi
Publikováno v:
Briefings in Bioinformatics. 24
Chromosomal translocations in cancer genomes, key players in many types of cancers, generate chimeric proteins that drive oncogenesis. Genomes with chromosomal rearrangements can also produce fusion circular RNAs (f-circRNAs) by backsplicing of chime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f731748901e12adeb50c5f4dee9fd9b8
https://doi.org/10.1093/bib/bbac589
https://doi.org/10.1093/bib/bbac589
Autor:
Alice Cani, Caterina Tretti Parenzan, Chiara Frasson, Elena Rampazzo, Pamela Scarparo, Samuela Francescato, Federico Caicci, Vito Barbieri, Antonio Rosato, Simone Cesaro, Marco Zecca, Concetta Micalizzi, Laura Sainati, Martina Pigazzi, Alessandra Biffi, Barbara Buldini, Franco Locatelli, Luca Persano, Riccardo Masetti, Geertruij te Kronnie, Silvia Bresolin
Publikováno v:
Blood advances.
Juvenile myelomonocytic leukemia (JMML) is a rare clonal stem cell disorder that occurs in early childhood and is characterized by the hyperactivation of the RAS pathway in 95% of the patients. JMML is characterized by a hyperproliferation of granulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ae1f83d9b08c4bbc619a718799fe8e
https://pubmed.ncbi.nlm.nih.gov/36053787
https://pubmed.ncbi.nlm.nih.gov/36053787
Autor:
Chiara Palmi, Silvia Bresolin, Stefanie V. Junk, Grazia Fazio, Daniela Silvestri, Marketa Zaliova, Athanasios Oikonomou, Katerina Scharov, Martin Stanulla, Anja Moericke, Martin Zimmermann, Martin Schrappe, Barbara Buldini, Claudia Saitta, Marta Galbiati, Michela Bardini, Sanil Bhatia, Arndt Borkhardt, Luca Lo Nigro, Valentino Conter, Maria Grazia Valsecchi, Andrea Biondi, Geertruij Te Kronnie, Gunnar Cario, Giovanni Cazzaniga
Publikováno v:
Blood. 140:6367-6368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931e7bed5587dd0152f52c470e817e0b
https://doi.org/10.1182/blood-2022-169131
https://doi.org/10.1182/blood-2022-169131
Autor:
Martin Zimmermann, Christoph Plass, Enrico Gaffo, Martin Schrappe, Stefanie Enzenmüller, Lueder H. Meyer, Dieter Weichenhan, Qian Sun, Judith M. Boer, Vera Münch, Rainer Claus, Salih Demir, Geertruij te Kronnie, Monique L. den Boer, Julia Zinngrebe, Elena Boldrin, Gunnar Cario, Stefania Bortoluzzi, Felix Seyfried, Klaus-Michael Debatin, Alexandra Niedermayer
We previously identified an association of rapid engraftment of patient-derived leukemia cells transplanted into NOD/SCID mice with early relapse in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In a search for the cellular and molecular p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7864e8c8a377c889ebf6c77a0cfaa0f
http://hdl.handle.net/11577/3394528
http://hdl.handle.net/11577/3394528
Autor:
Anna Dal Molin, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Hélène Cavé, Christian Flotho, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, Jan Philippé, Barbara De Moerloose, Geertruij te Kronnie, Silvia Bresolin, Tim Lammens, Stefania Bortoluzzi
Publikováno v:
Frontiers in Cell and Developmental Biology
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Juvenile myelomonocytic leukemia (JMML), a rare myelodysplastic/myeloproliferative neoplasm of early childhood, is characterized by clonal growth of RAS signaling addicted stem cells. JMML subtypes are defined by specific RAS pathway mutations and di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed526a5a31ebdcbbab368a41238cd155
https://pubmed.ncbi.nlm.nih.gov/33490078
https://pubmed.ncbi.nlm.nih.gov/33490078