Zobrazeno 1 - 10
of 450
pro vyhledávání: '"Geert-Jan Boons"'
Autor:
Luca Unione, Augustinus N. A. Ammerlaan, Gerlof P. Bosman, Elif Uslu, Ruonan Liang, Frederik Broszeit, Roosmarijn van der Woude, Yanyan Liu, Shengzhou Ma, Lin Liu, Marcos Gómez-Redondo, Iris A. Bermejo, Pablo Valverde, Tammo Diercks, Ana Ardá, Robert P. de Vries, Geert-Jan Boons
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Prototypic receptors for human influenza viruses are N-glycans carrying α2,6-linked sialosides. Due to immune pressure, A/H3N2 influenza viruses have emerged with altered receptor specificities that bind α2,6-linked sialosides presented on
Externí odkaz:
https://doaj.org/article/0d4875c4402b4ec5aabf0080d2503c78
Autor:
Shengzhou Ma, Lin Liu, Dirk Eggink, Sander Herfst, Ron A. M. Fouchier, Robert P. de Vries, Geert-Jan Boons
Publikováno v:
JACS Au, Vol 4, Iss 2, Pp 607-618 (2024)
Externí odkaz:
https://doaj.org/article/efb81e862c6348d388537b80ae742d74
Autor:
Simon P. J. de Jong, Zandra C. Felix Garza, Joseph C. Gibson, Sarah van Leeuwen, Robert P. de Vries, Geert-Jan Boons, Marliek van Hoesel, Karen de Haan, Laura E. van Groeningen, Katina D. Hulme, Hugo D. G. van Willigen, Elke Wynberg, Godelieve J. de Bree, Amy Matser, Margreet Bakker, Lia van der Hoek, Maria Prins, Neeltje A. Kootstra, Dirk Eggink, Brooke E. Nichols, Alvin X. Han, Menno D. de Jong, Colin A. Russell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract During the COVID-19 pandemic, levels of seasonal influenza virus circulation were unprecedentedly low, leading to concerns that a lack of exposure to influenza viruses, combined with waning antibody titres, could result in larger and/or more
Externí odkaz:
https://doaj.org/article/2195d551308e41c0a9d1154b00ba6a9b
Autor:
Yunfei Wu, Gaël M. Vos, Chin Huang, Digantkumar Chapla, Anne L. M. Kimpel, Kelley W. Moremen, Robert P. de Vries, Geert-Jan Boons
Publikováno v:
JACS Au, Vol 3, Iss 11, Pp 3155-3164 (2023)
Externí odkaz:
https://doaj.org/article/f2fdf30d0b23483698599cd8c7cb2e5e
Autor:
Gaёl M. Vos, Kevin C. Hooijschuur, Zeshi Li, John Fjeldsted, Christian Klein, Robert P. de Vries, Javier Sastre Toraño, Geert-Jan Boons
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract O-acetylation is a common modification of sialic acids that has been implicated in a multitude of biological and disease processes. A lack of analytical methods that can determine exact structures of sialic acid variants is a hurdle to deter
Externí odkaz:
https://doaj.org/article/033979f4999e416c953fd011e0e3a6b2
Autor:
Hailee R. Perrett, Philip J.M. Brouwer, Jonathan Hurtado, Maddy L. Newby, Lin Liu, Helena Müller-Kräuter, Sarah Müller Aguirre, Judith A. Burger, Joey H. Bouhuijs, Grace Gibson, Terrence Messmer, John S. Schieffelin, Aleksandar Antanasijevic, Geert-Jan Boons, Thomas Strecker, Max Crispin, Rogier W. Sanders, Bryan Briney, Andrew B. Ward
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112524- (2023)
Summary: Lassa fever is an acute hemorrhagic fever caused by the zoonotic Lassa virus (LASV). The LASV glycoprotein complex (GPC) mediates viral entry and is the sole target for neutralizing antibodies. Immunogen design is complicated by the metastab
Externí odkaz:
https://doaj.org/article/42bc3a303aa044c8bb858af2181c5575
Autor:
M. Osman Sheikh, Chantelle J. Capicciotti, Lin Liu, Jeremy Praissman, Dahai Ding, Daniel G. Mead, Melinda A. Brindley, Tobias Willer, Kevin P. Campbell, Kelley W. Moremen, Lance Wells, Geert-Jan Boons
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Matriglycan, a repeating disaccharide on α-dystroglycan, is the receptor for Lassa virus and specific extracellular matrix proteins. Here, the authors demonstrate that matriglycan, in a length-dependent tunable manner, is both necessary and sufficie
Externí odkaz:
https://doaj.org/article/6f16e38680614cf4be0f9a79a71c7b0f
Autor:
David Scheibner, Ahmed H Salaheldin, Ola Bagato, Luca M Zaeck, Ahmed Mostafa, Ulrike Blohm, Christin Müller, Ahmed F Eweas, Kati Franzke, Axel Karger, Alexander Schäfer, Marcel Gischke, Donata Hoffmann, Solène Lerolle, Xuguang Li, Hatem S Abd El-Hamid, Jutta Veits, Angele Breithaupt, Geert-Jan Boons, Mikhail Matrosovich, Stefan Finke, Stephan Pleschka, Thomas C Mettenleiter, Robert P de Vries, Elsayed M Abdelwhab
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011135 (2023)
Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in
Externí odkaz:
https://doaj.org/article/5e67914c60d94bd3bdd8f58ed3fa88db
Autor:
Nicolas Gaide, Marie-Noëlle Lucas, Mattias Delpont, Guillaume Croville, Kim M. Bouwman, Andreas Papanikolaou, Roosmarijn van der Woude, Iwan A. Gagarinov, Geert-Jan Boons, Robert P. De Vries, Romain Volmer, Angélique Teillaud, Timothée Vergne, Céline Bleuart, Guillaume Le Loc’h, Maxence Delverdier, Jean-Luc Guérin
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-15 (2022)
Abstract In late 2015, an epizootic of Highly Pathogenic Avian Influenza (H5Nx) was registered in Southwestern France, including more than 70 outbreaks in commercial poultry flocks. Phylogenetic analyses suggested local emergence of H5 viruses which
Externí odkaz:
https://doaj.org/article/93c73a4567934467a6e2488ea1b21fdd
Autor:
Guha Asthagiri Arunkumar, Disha Bhavsar, Tiehai Li, Shirin Strohmeier, Veronika Chromikova, Fatima Amanat, Mehman Bunyatov, Patrick C. Wilson, Ali H. Ellebedy, Geert-Jan Boons, Viviana Simon, Robert P. de Vries, Florian Krammer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The recently identified Wuhan spiny eel influenza virus (WSEIV) sequence is more closely related to influenza B than A viruses. Here, the authors functionally characterize the putative surface glycoproteins of WSEIV and show that its NA-like protein
Externí odkaz:
https://doaj.org/article/7d019ab5c90341b1b42cb0b05de64f8d