Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Geert Michel"'
Autor:
Raffaella Simone, Daniel Čižmár, Susanne Holtze, Geert Michel, Anje Sporbert, Charlotte Okolo, Thomas B. Hildebrandt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The African naked mole-rat (Heterocephalus glaber) is an attractive model for cancer and aging research due to its peculiar biological traits, such as unusual long life span and resistance to cancer. The establishment of induced pluripotent
Externí odkaz:
https://doaj.org/article/8f8602e315804c4f8ab18faf6a286666
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1779 (2024)
Patients with mutations in Cldn16 suffer from familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) which can lead to renal insufficiency. Mice lacking claudin-16 show hypomagnesemia and hypercalciuria, but no nephrocalcinosis. Ca
Externí odkaz:
https://doaj.org/article/5b50a7f07e0f4a56acd99920984a4874
Autor:
Vera Zywitza, Ejona Rusha, Dmitry Shaposhnikov, Jorge Ruiz-Orera, Narasimha Telugu, Valentyna Rishko, Masafumi Hayashi, Geert Michel, Lars Wittler, Jan Stejskal, Susanne Holtze, Frank Göritz, Robert Hermes, Jichang Wang, Zsuzsanna Izsvák, Silvia Colleoni, Giovanna Lazzari, Cesare Galli, Thomas B. Hildebrandt, Katsuhiko Hayashi, Sebastian Diecke, Micha Drukker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract The northern white rhinoceros (NWR) is probably the earth’s most endangered mammal. To rescue the functionally extinct species, we aim to employ induced pluripotent stem cells (iPSCs) to generate gametes and subsequently embryos in vitro.
Externí odkaz:
https://doaj.org/article/7d2718019bd844b08e9b1dd694becabd
Autor:
Mariana Soria-Tiedemann, Geert Michel, Iris Urban, Maceler Aldrovandi, Valerie B. O’Donnell, Sabine Stehling, Hartmut Kuhn, Astrid Borchert
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9907 (2022)
Glutathione peroxidase 4 (Gpx4) and arachidonic acid 15 lipoxygenase (Alox15) are counterplayers in oxidative lipid metabolism and both enzymes have been implicated in spermatogenesis. However, the roles of the two proteins in acrosomal exocytosis ha
Externí odkaz:
https://doaj.org/article/4ce1805d41dc4bd4b508bf95b9c58567
Autor:
Franziska Weiß, Carolina Czichos, Lukas Knobe, Lena Voges, Christian Bojarski, Geert Michel, Michael Fromm, Susanne M. Krug
Publikováno v:
Cells, Vol 11, Iss 9, p 1541 (2022)
In inflammatory bowel disease (IBD), the impaired intestinal barrier is mainly characterized by changes in tight junction protein expression. The functional role of the tight junction-associated MARVEL protein MARVELD3 (MD3) in IBD is yet unknown. (i
Externí odkaz:
https://doaj.org/article/03b91fb12b674c1abe50447e18dc4c27
Autor:
Borchert, Mariana Soria-Tiedemann, Geert Michel, Iris Urban, Maceler Aldrovandi, Valerie O’Donnell, Sabine Stehling, Hartmut Kuhn, Astrid
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9907
Glutathione peroxidase 4 (Gpx4) and arachidonic acid 15 lipoxygenase (Alox15) are counterplayers in oxidative lipid metabolism and both enzymes have been implicated in spermatogenesis. However, the roles of the two proteins in acrosomal exocytosis ha
Autor:
Sophia, Borowski, Nancy, Freitag, Iris, Urban, Geert, Michel, Gabriela, Barrientos, Sandra M, Blois
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2442
Galectin-1 (gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, is differentially expressed at the feto-maternal interface and appears to be functionally polyvalent, with a wide range of biological activities. However, t
Autor:
Sophia Borowski, Nancy Freitag, Iris Urban, Geert Michel, Gabriela Barrientos, Sandra M. Blois
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcaa2ac8b72f9dcfa191ef6323546cff
https://doi.org/10.1007/978-1-0716-2055-7_32
https://doi.org/10.1007/978-1-0716-2055-7_32
Publikováno v:
Theriogenology. 114:85-94
We determined the effect of monogamous or polygamous mating with 2 females on vaginal plug (VP) rate, embryo donors (ED), 2-cell embryo production, and male performance after superovulation of females aging 24d or 45-48d. C57BL/6NCrl (B6N), BALB/cAnC
Autor:
Sibylle Mitschka, F. Gregory Wulczyn, Geert Michel, Duong Thi Thuy Nguyen, Waldemar Kolanus, Elisa Cuevas, Daniel Richter
Publikováno v:
Cell Death and Differentiation
Rapidity and specificity are characteristic features of proteolysis mediated by the ubiquitin-proteasome system. Therefore, the UPS is ideally suited for the remodeling of the embryonic stem cell proteome during the transition from pluripotent to dif