Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Geert M. E. Pille"'
Autor:
Dominique Louis Nestor Ghislain Surleraux, Anik Peeters, Sandra De Meyer, Rudi Wilfried Jan Pauwels, Moses Prabu-Jeyabalan, Piet Wigerinck, Celia A. Schiffer, Geert M. E. Pille, Hilde Azijn, Louis J. R. Maes, Herman Augustinus De Kock, Sandrine Marie Helene Vendeville, Wim Gaston Verschueren, Marie-Pierre de Béthune, Nancy M. King
Publikováno v:
Journal of medicinal chemistry
On the basis of structural data gathered during our ongoing HIV-1 protease inhibitors program, from which our clinical candidate TMC114 9 was selected, we have discovered new series of fused heteroaromatic sulfonamides. The further extension into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd8542a3b133ceedb9a93cedbed6ccb
https://doi.org/10.1021/jm049454n
https://doi.org/10.1021/jm049454n
Autor:
Geert M. E. Pille, Kurt Hertogs, Katie I. E. Amssoms, Lili Hu, Inge Dierynck, Paul M. J. G. Boonants, Wim G. Verschueren, Frits Daeyaert, Surleraux Dominique Louis Nest, Piet Wigerinck
Publikováno v:
Journal of medicinal chemistry. 48(6)
Human immunodeficiency virus type-1 integrase is an essential enzyme for effective viral replication and hence a valid target for the design of inhibitors. We report here on the design and synthesis of a novel series of phthalimide analogues as integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274df4da41f37adc5df37a109d8df7b3
https://pubmed.ncbi.nlm.nih.gov/15771437
https://pubmed.ncbi.nlm.nih.gov/15771437