Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Geert J.C.M. Kolvenbag"'
Autor:
Anthony Nash, Geert J.C.M. Kolvenbag
Publikováno v:
The Prostate. 39:47-53
BACKGROUND Androgen deprivation is often used for the treatment of patients with prostate cancer. Androgen deprivation can be achieved by surgical castration or medical castration, with or without using an antiandrogen. Each of these treatments may b
Autor:
Michael F. Sarosdy, Eric A. Klein, Peter Venner, Gerald W. Chodak, Mark S. Soloway, A. Lynn Patterson, Julie Jones Schellenger, Norman L. Block, Geert J.C.M. Kolvenbag, Roohollah Sharifi, Paul F. Schellhammer, Nicholas J. Vogelzang
Publikováno v:
Urology. 52:82-88
Objectives. To perform exploratory analyses of data from a controlled trial that assessed the efficacy and tolerability of two antiandrogens, bicalutamide and flutamide, each combined with monthly depot preparations of leuprolide or goserelin, in pat
Publikováno v:
The Prostate. 34:61-72
BACKGROUND Bicalutamide (Casodex®) is a new nonsteroidal antiandrogen developed for use in patients with prostate cancer. The efficacy and tolerability of bicalutamide as monotherapy and as combination therapy for patients with advanced prostate can
Autor:
Peter Venner, Michael F. Sarosdy, Paul F. Schellhammer, Roohollah Sharifi, Mark S. Soloway, A. Lynn Patterson, Nicholas J. Vogelzang, Julie Jones Schellenger, Geert J.C.M. Kolvenbag, Norman L. Block
Publikováno v:
Urology. 50:330-336
Objectives To compare the efficacy and tolerability of bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue (LHRH-A) therapy, in patients with metastatic (Stage D2) prostate cancer. Methods This was a randomiz
Autor:
Zev Wajsman, Eric Klein, Peter N. Venner, Paul F. Schellhammer, A. Lynn Patterson, Peter T. Nieh, Yusong Chen, D. Rusby Seabaugh, Eric J. Small, Gabriel P. Haas, Geert J.C.M. Kolvenbag, Barry Furr
Publikováno v:
Journal of Urology. 157:1731-1735
Purpose: We determined whether decreases in prostate specific antigen (PSA) would occur after withdrawal of double-blinded antiandrogen therapy with flutamide or bicalutamide for clinical progression or increasing PSA concentration in patients receiv
Autor:
Geert J.C.M. Kolvenbag, Gerhard A. Dijkman, Wim P.J. Witjes, Frans M.J. Debruyne, Pilar Fernandez del Moral
Publikováno v:
Urology, 48, 6, pp. 894-900
Urology, 48, 894-900
Urology, 48, 894-900
Objectives. To compare the pharmacodynamics and tolerability of the new goserelin acetate 10.6mg depot with the 3.6-mg depot in patients with advanced prostate cancer during the first 3 months of therapy. Methods. One hundred sixty patients were rand
Publikováno v:
Anti-Cancer Drugs. 7:27-34
Maximum androgen blockade, a relatively recent development in the treatment of prostate cancer, combines medical or surgical castration with antiandrogen therapy. A large randomized study comparing the non-steroidal antiandrogen, bicalutamide, with f
Autor:
Nicholas J. Vogelzang, A.L. Patterson, Geert J.C.M. Kolvenbag, J.A. Jones, Mark S. Soloway, Paul F. Schellhammer, Michael F. Sarosdy, Roohollah Sharifi, P.M. Venner
Publikováno v:
European Urology. 29:105-109
Between January 1992 and September 1993, 813 patients with stage D2 prostate cancer were enrolled in a multicentre, double-blind (for antiandrogen therapy) trial and randomised to antiandrogen therapy with Casodex (bicalutamide, 50 mg once daily) or
Publikováno v:
Urology. 47:70-79
To evaluate bicalutamide as a therapy in nearly 3000 patients with advanced prostate cancer and to determine the dose-ranging, pharmacodynamic, and pharmacokinetic properties of bicalutamide. To evaluate bicalutamide as a monotherapy or in combinatio
Autor:
Nicholas Vogelzang, Norman Block, Julie Jones, Roohollah Sharifi, Michael Sarosdy, Peter Venner, A. Lynn Patterson, Mark Soloway, Paul F. Schellhammer, Geert J.C.M. Kolvenbag
Publikováno v:
Urology. 45:745-752
Objectives To compare the efficacy and safety of bicalutamide and flutamide, each used in combination with luteinizing hormone-releasing hormone analogue (LHRH-A) therapy, in patients with untreated metastatic (Stage D2) prostate cancer.