Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Geert Leroux-Roels"'
Autor:
Valentino D’Onofrio, Sharon Porrez, Bart Jacobs, Azhar Alhatemi, Fien De Boever, Gwenn Waerlop, Els Michels, Francesca Vanni, Alessandro Manenti, Geert Leroux-Roels, Peter Paul Platenburg, Luuk Hilgers, Isabel Leroux-Roels
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1036 (2024)
Seasonal influenza vaccine effectiveness is low. Carbohydrate fatty acid monosulphate ester (CMS), a new oil-in-water adjuvant, has proven potency in animal models with suggested capacity for dose-sparing. The objective was to evaluate safety and imm
Externí odkaz:
https://doaj.org/article/5ca3304e712c41af9db534402afe1e73
Autor:
Elien Vandoorn, Wojciech Stadejek, Isabel Leroux-Roels, Geert Leroux-Roels, Anna Parys, Kristien Van Reeth
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 1, Pp 98-109 (2023)
Influenza A viruses (IAVs) of subtype H3 that infect humans are antigenically divergent from those of birds, horses, and swine. Human immunity against these viruses might be limited, implying potential pandemic risk. To determine human risk, we selec
Externí odkaz:
https://doaj.org/article/75dc792e1cc34b58a2b3c555786e72dd
Autor:
Xavier Sáez-Llorens, Claudio Lanata, Elaine Aranguren, Carlos R. Celis, Rubelio Cornejo, Rodrigo DeAntonio, Lucie Ecker, Diegi Garrido, Ana I. Gil, Marina Gonzales, Morgan Hess-Holtz, Geert Leroux-Roels, Helga Junker, Sarah-Katharina Kays, Sven D. Koch, Sandra Lazzaro, Philipp Mann, Gianluca Quintini, Barkha Srivastava, Dominik Vahrenhorst, Philipp von Eisenhart-Rothe, Olaf-Oliver Wolz, Lidia Oostvogels
Publikováno v:
Vaccine: X, Vol 14, Iss , Pp 100307- (2023)
Externí odkaz:
https://doaj.org/article/b348038516694a90b653418856f6e575
Autor:
Gwenn Waerlop, Yorick Janssens, Bart Jacobs, Franziska Jarczowski, André Diessner, Geert Leroux-Roels, Victor Klimyuk, Isabel Leroux-Roels, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The development of an efficacious vaccine against norovirus is of paramount importance given its potential to reduce the global burden of norovirus-associated morbidity and mortality. Here, we report a detailed immunological analysis of a phase I, do
Externí odkaz:
https://doaj.org/article/f7335b481858407fbb8da1fd8c01564b
Autor:
Rani Burm, Freya Van Houtte, Lieven Verhoye, Ahmed Atef Mesalam, Sandra Ciesek, Philippe Roingeard, Heiner Wedemeyer, Geert Leroux-Roels, Philip Meuleman
Publikováno v:
JHEP Reports, Vol 5, Iss 3, Pp 100646- (2023)
Background & Aims: Elimination of chronic HBV/HDV infection remains a major global health challenge. Targeting excessive hepatitis B surface antigen (HBsAg) release may provide an interesting window of opportunity to break immune tolerance and to ach
Externí odkaz:
https://doaj.org/article/2d07be3d73284b0680e2c8f9f411a48c
Autor:
Julia Strandmark, Alansana Darboe, Joann Diray-Arce, Rym Ben-Othman, Sofia M. Vignolo, Shun Rao, Kinga K. Smolen, Geert Leroux-Roels, Olubukola T. Idoko, Guzmán Sanchez-Schmitz, Al Ozonoff, Ofer Levy, Tobias R. Kollmann, Arnaud Marchant, Beate Kampmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A single birth-dose of Hepatitis B vaccine (HepB) can protect newborns from acquiring Hepatitis B infection through vertical transmission, though several follow-up doses are required to induce long-lived protection. In addition to stimulating antibod
Externí odkaz:
https://doaj.org/article/18f04a70e1674e919905aded5c30ad0c
Autor:
Isabel Leroux-Roels, Cathy Maes, Jasper Joye, Bart Jacobs, Franziska Jarczowski, André Diessner, Yorick Janssens, Gwenn Waerlop, Kirsi Tamminen, Suvi Heinimäki, Vesna Blazevic, Geert Leroux-Roels, Victor Klimyuk, Hiroshi Adachi, Kazuyuki Hiruta, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide and a safe and effective vaccine is needed. Here, a phase I, double-blind, placebo-controlled clinical trial was performed in 60 healthy adults, 18 to 40 ye
Externí odkaz:
https://doaj.org/article/bb6df2d5e1e744729c3ccc75dafbda24
Autor:
Sarah Begue, Gwenn Waerlop, Bruno Salaun, Michel Janssens, Duncan Bellamy, Rebecca Jane Cox, Richard Davies, Elena Gianchecchi, Donata Medaglini, Emanuele Montomoli, Elena Pettini, Geert Leroux-Roels, Frédéric Clement, Anke Pagnon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the knowledge that cell-mediated immunity (CMI) contributes to the reduction of severe influenza infection, transmission, and disease outcome, the correlates of protection for cell-mediated immunity remain still unclear. Therefore, measuring
Externí odkaz:
https://doaj.org/article/c403b38c5ac8489a863b3b4df632aebc
Autor:
Gwenn Waerlop, Geert Leroux-Roels, Teresa Lambe, Duncan Bellamy, Donata Medaglini, Elena Pettini, Rebecca Jane Cox, Mai-Chi Trieu, Richard Davies, Geir Bredholt, Emanuele Montomoli, Elena Gianchecchi, Frédéric Clement
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Influenza continues to be the most important cause of viral respiratory disease, despite the availability of vaccines. Today’s evaluation of influenza vaccines mainly focuses on the quantitative and functional analyses of antibodies to the surface
Externí odkaz:
https://doaj.org/article/116eaa57d6974bae96f9ea8a97ba3ede
Autor:
Yorick Janssens, Jasper Joye, Gwenn Waerlop, Frédéric Clement, Geert Leroux-Roels, Isabel Leroux-Roels
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Influenza vaccines remain the most effective tools to prevent flu and its complications. Trivalent or quadrivalent inactivated influenza vaccines primarily elicit antibodies towards haemagglutinin and neuraminidase. These vaccines fail to induce high
Externí odkaz:
https://doaj.org/article/262c4faa458545149a31be97fec53a78