Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Geeng Fu Jang"'
Autor:
Geeng-Fu Jang, John S. Crabb, Allison Grenell, Alyson Wolk, Christie Campla, Shiming Luo, Mariya Ali, Bo Hu, Belinda Willard, Bela Anand-Apte
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Sex as a biological variable is not a common consideration in molecular mechanistic or preclinical studies of retinal diseases. Understanding the sexual dimorphism of adult RPE and retina under physiological conditions is an impor
Externí odkaz:
https://doaj.org/article/365d699ba72941d99ccd615aeb44498c
Autor:
Allison Grenell, Charandeep Singh, Monisha Raju, Alyson Wolk, Sonal Dalvi, Geeng-Fu Jang, John S. Crabb, Courtney E. Hershberger, Kannan V. Manian, Karen Hernandez, John W. Crabb, Ruchira Singh, Jianhai Du, Bela Anand-Apte
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 101995- (2024)
Objectives: Mutations in Tissue Inhibitor of Metalloproteinases 3 (TIMP3) cause Sorsby's Fundus Dystrophy (SFD), a dominantly inherited, rare form of macular degeneration that results in vision loss. TIMP3 is synthesized primarily by retinal pigment
Externí odkaz:
https://doaj.org/article/b2e34dbdf5864329895d170e3ed2ee8a
Autor:
Steven E. Wilson, Madison J Juszczak, Luciana L Dibbin, Jack S Crabb, Thomas Michael Shiju, Belinda Willard, Geeng-Fu Jang, John W. Crabb, Paramananda Saikia
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Myofibroblasts are fibroblastic cells that function in wound healing, tissue repair and fibrosis, and arise from bone marrow (BM)-derived fibrocytes and a variety of local progenitor cells. In the cornea, myofibroblasts are derived primarily from str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5c686a436483031baa21ae057d59fc
http://link.springer.com/article/10.1038/s41598-020-73686-w
http://link.springer.com/article/10.1038/s41598-020-73686-w
Autor:
Geeng Fu Jang, John W. Crabb, Vladlen Z. Slepak, Alexey Pronin, Camila Lubaczeuski, Taylor Henry, Qiang Wang, Ernesto Bernal-Mizrachi
Publikováno v:
J Biol Chem
G protein–coupled receptors (GPCRs) are important modulators of glucose-stimulated insulin secretion, essential for maintaining energy homeostasis. Here we investigated the role of Gβ5–R7, a protein complex consisting of the atypical G protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b572449a8344c46e3d5aab3c0b0046b
https://doi.org/10.1074/jbc.ra119.011534
https://doi.org/10.1074/jbc.ra119.011534
Autor:
Jack S Crabb, Bo Hu, Geeng-Fu Jang, Belinda Willard, Sarah E. Coupland, Helen Kalirai, Arun D. Singh, John W. Crabb
Publikováno v:
Cancers
CANCERS
Volume 13
Issue 14
Cancers, Vol 13, Iss 3520, p 3520 (2021)
CANCERS
Volume 13
Issue 14
Cancers, Vol 13, Iss 3520, p 3520 (2021)
Simple Summary This study pursued the proteomic analysis of primary uveal melanoma (pUM) for insights into the mechanisms of metastasis and protein biomarkers. Liquid chromatography tandem mass spectrometry quantitative proteomic technology was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e143cc3c26f5f1559da0547ab975103b
https://pubmed.ncbi.nlm.nih.gov/34298739
https://pubmed.ncbi.nlm.nih.gov/34298739
Autor:
John W. Crabb, Alexey Pronin, Qiang Wang, Vladlen Z. Slepak, Ernesto Bernal-Misrachi, Camila Lubaczeuski, Geeng-Fu Jang, Taylor Henry
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e5d012f959307156a1b2adc3f68d71
https://doi.org/10.1096/fasebj.2020.34.s1.02604
https://doi.org/10.1096/fasebj.2020.34.s1.02604
Autor:
Junhong Guo, Mikhail Linetsky, Clinical Genomic, Hua Wang, Liang Lu, Lei Zhang, Li Hong, John W. Crabb, Hemant K. Bid, Xiaoxia Z. West, Geeng-Fu Jang, Robert G. Salomon
Publikováno v:
Chemical Research in Toxicology
Oxidation of docosahexaenoate phospholipids produces 4-hydroxy-7-oxo-hept-5-eonyl phospholipids (HOHA-PLs) that react with protein lysyl e-amino residues to generate 2-ω-carboxyethylpyrrole (CEP) derivatives, endogenous factors that induce angiogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456486abe1bdb35c4a23c5aa850616a0
http://europepmc.org/articles/PMC4269404
http://europepmc.org/articles/PMC4269404
Autor:
Vladlen Z. Slepak, Cesare Orlandi, Qiang Wang, Geeng Fu Jang, John W. Crabb, Kirill A. Martemyanov, Alexey Pronin, Junior Tayou
Publikováno v:
The Journal of biological chemistry. 291(17)
RGS (regulator of G protein signaling) proteins of the R7 subfamily (RGS6, -7, -9, and -11) are highly expressed in neurons where they regulate many physiological processes. R7 RGS proteins contain several distinct domains and form obligatory dimers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a8c39bd2e8e82e10494630cfa6b8b
https://pubmed.ncbi.nlm.nih.gov/26895961
https://pubmed.ncbi.nlm.nih.gov/26895961
Akademický článek
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Autor:
Martin Heck, Tadao Maeda, Michael H. Gelb, Yan Liang, Eglof Ritter, Geeng-Fu Jang, Slawomir Filipek, Vladimir A. Kuksa, Franz Bartl, Krzysztof Palczewski, J. Preston Van Hooser, Klaus Peter Hofmann
Publikováno v:
Journal of Biological Chemistry. 277:42315-42324
Phototransduction is initiated by the photoisomerization of rhodopsin (Rho) chromophore 11-cis-retinylidene to all-trans-retinylidene. Here, using Rho regenerated with retinal analogs with different ring sizes, which prevent isomerization around the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d0ce89f5184dc83f073281d9006cd1
https://doi.org/10.1074/jbc.m206014200
https://doi.org/10.1074/jbc.m206014200