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Optimized Methods for the Production and Bioconjugation of Site-Specific, Alkyne-Modified Glucagon-like Peptide-1 (GLP-1) Analogs to Azide-Modified Delivery Platforms Using Copper-Catalyzed Alkyne–Azide Cycloaddition

Autor: Seyed Ebrahim Alavi, Peter M. Moyle, Gee Yi Yap, Peter J. Cabot

Publikováno v: Bioconjugate Chemistry. 31:1820-1834

This study aimed to develop and optimize chemistries to produce alkyne-modified glucagon-like peptide-1(7-36)-amide (GLP-1(7-36)-NH2) libraries, which could be rapidly and efficiently conjugated to other components and screened to identify compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01fafd5fecfa889c69901288191d285
https://doi.org/10.1021/acs.bioconjchem.0c00291

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Akademický článek

Optimized Methods for the Production and Bioconjugation of Site-Specific, Alkyne-Modified Glucagon-like Peptide‑1 (GLP-1) Analogs to Azide-Modified Delivery Platforms Using Copper-Catalyzed Alkyne–Azide Cycloaddition.

Autor: Ebrahim Alavi, Seyed, Cabot, Peter John, Gee Yi Yap, Moyle, Peter Michael

Publikováno v: Bioconjugate Chemistry; 7/15/2020, Vol. 31 Issue 7, p1820-1834, 15p

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