Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gee Fung How"'
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100219- (2023)
Externí odkaz:
https://doaj.org/article/d59f9e4061ea474f899329fe724a8e8d
Publikováno v:
Leukemia Research. 32:169-171
Patients with primary hypereosinophilic disorders who are positive for the FIP1L1-PDGFRA fusion gene mutation are highly responsive to therapy with imatinib mesylate. A 35-year-old man with FIP1L1-PDGFRA positive hypereosinophilic syndrome and cardia
Autor:
Naoto Takahashi, V. S. Nadarajan, Yijun Ruan, Anbupalam Thalamuthu, Wing-Kin Sung, Xing Yi Woo, Hae Tha Mya, Sheila Soh, Xiaoan Ruan, Wen Chun Juan, Kazutoshi Isobe, Markus M. Nöthen, Wan-Teck Lim, John W.J. Huang, Hein Than, Yao Fei, L.Y. Yang, Chia-Tien Chang, Dianne Poh, Noan-Minh Chau, Axel M. Hillmer, Liang Piu Koh, Ai Leen Ang, Gee Fung How, Mei-Kim Ang, Yeow Tee Goh, Lay Cheng Lim, Tan Min Chin, Daniel Shao-Weng Tan, Wee Joo Chng, Balram Chowbay, Audrey S.M. Teo, Hiroyuki Mano, Ju Ee Seet, Niranjan Nagarajan, Quan Sing Ng, Shenli Zhang, Pramila N. Ariyaratne, Atif Shahab, Wan Ting Poh, Manabu Soda, Patrick Tan, Yasushi Yatabe, Kenichi Sawada, Vikrant Kumar, Ross A. Soo, Tien Yin Wong, Valere Cacheux-Rataboul, Charles Chuah, Eng Huat Tan, John Carson Allen, King Pan Ng, Wah Heng Lee, S. Tiong Ong, Tun Kiat Ko
Publikováno v:
Nature medicine. 18(4)
Tyrosine kinase inhibitors (TKIs) elicit high response rates among individuals with kinase-driven malignancies, including chronic myeloid leukemia (CML) and epidermal growth factor receptor-mutated non-small-cell lung cancer (EGFR NSCLC). However, th
Publikováno v:
Journal of Physical Organic Chemistry. 4:707-713
The Z/E photoisomerization of a series of 5-arylmethylenehydantoins and a series of 5-pyridylmethylenehydantoins by direct irradiation in methanol or ethanol solvent was investigated. The isomeric ratios at the photostationary state are dependent on
Publikováno v:
Journal of Physical Organic Chemistry. 4:681-688
Two series of 5-furylmethylenehydantoins and 5-thienylmethylenehydantoins were prepared and their 1H and 13C NMR spectra studied in comparison with those of compounds in the analogous 5-aryl- and 5-pyridyl- series. Differences in the effects of the a
Intermolecular and intramolecular hydrogen bonding in 5-pyridylmethylenehydantoins: IR and NMR study
Publikováno v:
Journal of Physical Organic Chemistry. 4:170-176
The patterns of the NH stretching vibrations in the solid-state IR spectra of a series of 5-pyridylmethylenehydantoins revealed the presence of various modes of hydrogen bonding: intermolecular NH&4nldr; &4nldr;OC and intermolecular or intramolecular
Ionization constants of 5-pyridylmethylenehydantoins in 80% (w/w) dimethyl sulphoxide-water at 25 °C
Publikováno v:
Journal of Physical Organic Chemistry. 3:703-710
The ionization constants of nine amphoteric 5-pyridylmethylenehydantoins were measured in 80% (w/w) dimethyl sulphoxide–water at 25 °C. The effects of structure and Z/E configuration on both pK and pK values are discussed. The especially low basic
Publikováno v:
Journal of Physical Organic Chemistry. 3:559-566
Nine 5-pyridylmethylenehydantoins were prepared. Each of the 1-methyl-substitute compounds was obtained in two stereoisomeric forms. Only one form of each of the 3-methyl-substituted and N-unsubstituted compounds was obtained directly from synthesis
Publikováno v:
British Journal of Haematology. 157:131-132
Autor:
L. H. Lee, C Dearden, Gerrard Teoh, S.M. Loh, William Hwang, Gee Fung How, P.X. Liew, Sim-Leng Tien, L.F. Lim, Y C Linn, K.K. Heng, Yeow-Tee Goh
Publikováno v:
Blood. 108:4992-4992
Chronic lymphoproliferative disorders are considered rare in Asian countries. A recent 3-year study of 342 consecutive leukemia patients from 2 regional hospitals in Hong Kong, however, showed that CLL was diagnosed in 19% of Chinese patients with le