Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gediminas Staigvila"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2023)
Electroporation is an effective physical method for irreversible or reversible permeabilization of plasma membranes of biological cells and is typically used for tissue ablation or targeted drug/DNA delivery into living cells. In the context of cance
Externí odkaz:
https://doaj.org/article/7d261e9c77b945ebbd887663acb0c015
Autor:
Vitalij Novickij, Eglė Lastauskienė, Gediminas Staigvila, Irutė Girkontaitė, Auksė Zinkevičienė, Jurgita Švedienė, Algimantas Paškevičius, Svetlana Markovskaja, Jurij Novickij
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Skin infections, particularly caused by drug-resistant pathogens, represent a clinical challenge due to being a frequent cause of morbidity and mortality. The objectives of this study were to examine if low concentrations of aceti
Externí odkaz:
https://doaj.org/article/98e9e5b65672455ca16be6550b53d737
Autor:
Vitalij Novickij, Gediminas Staigvila, Arūnas Murauskas, Nina Rembialkowska, Julita Kulbacka, Jurij Novickij
Publikováno v:
Applied Sciences, Vol 12, Iss 3, p 1370 (2022)
In this work, a novel electroporation system (electroporator) is presented, which is capable of forming high frequency pulses in a broad range of parameters (65 ns–100 µs). The electroporator supports voltages up to 3 kV and currents up to 40 A an
Externí odkaz:
https://doaj.org/article/4e0d172c4f9343e2a68593c1faaba5c3
Autor:
J. Melesko, Matej Kranjc, Damijan Miklavčič, Vitalij Novickij, Janja Dermol-Černe, Gediminas Staigvila, Jurij Novickij
Publikováno v:
IEEE Transactions on Magnetics. 56:1-6
High-intensity pulsed electromagnetic fields (HI-PEMFs) can be used for contactless permeabilization of biological cells and, thus, exploited for drug and gene delivery or other biomedical applications. Nevertheless, the availability of applicable te
Autor:
Gediminas Staigvila, Irutė Girkontaitė, Renata Gudiukaitė, Jurgita Švedienė, Jurij Novickij, Vitalij Novickij, Algimantas Paškevičius, Eglė Lastauskienė, Svetlana Markovskaja, Auksė Zinkevičienė
Publikováno v:
Bioelectrochemistry. 128:148-154
Antifungal substances that are used for the treatment of candidiasis have considerable side effects and Candida yeasts are known to obtain drug resistance. The multidrug resistance cases are promoting the search for the new alternative methods and pu
Publikováno v:
IEEE Transactions on Magnetics. 55:1-5
The emerging contactless cell membrane permeabilization methodology (magnetoporation) based on high pulsed magnetic field (PMF) is highly dependent on the applied pulse parameters. Due to the lack of magnetic experimental infrastructure, the parametr
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
In the present study, we report the effects of extracellular medium conductivity on cell response in the context of sub-microsecond range (100 ns–900 ns) electroporation, calcium electroporation and cell size. The effects of 25 ns and microsecond r
Autor:
Saulius Šatkauskas, Auksė Zinkevičienė, Irutė Girkontaitė, Arūnas Murauskas, Paulius Ruzgys, Vitalij Novickij, Gediminas Staigvila, Jurij Novickij
Publikováno v:
Electromagnetic biology and medicine. 39(1)
Measurement of cell transmembrane potential (TMP) is a complex methodology involving patch-clamp methods or fluorescence-based potentiometric markers, which have limited to no applicability during ultrafast charging and relaxation phenomena. In such
Autor:
Audrius Grainys, Algimantas Paškevičius, Svetlana Markovskaja, Gediminas Staigvila, Jurij Novickij, Vitalij Novickij, Eglė Lastauskienė, Auksė Zinkevičienė, Irutė Girkontaitė, Jurgita Švedienė
Publikováno v:
The Journal of Membrane Biology. 251:189-195
Recently, a novel contactless treatment method based on high-power pulsed electromagnetic fields (PEMF) was proposed, which results in cell membrane permeabilization effects similar to electroporation. In this work, a new PEMF generator based on mult