Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Gedeon, Tomas"'
We present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model. There are two monotone nonlinearities in the model: one describes the
Externí odkaz:
http://arxiv.org/abs/2410.13092
We introduce two time-delay models of metabolic oscillations in yeast cells. Our model tests a hypothesis that the oscillations occur as multiple pathways share a limited resource which we equate to the number of available ribosomes. We initially exp
Externí odkaz:
http://arxiv.org/abs/2305.07643
In this paper we investigate the convexity of the relevance-compression function for the Information Bottleneck and the Information Distortion problems. This curve is an analog of the rate-distortion curve, which is convex. In the problems we discuss
Externí odkaz:
http://arxiv.org/abs/2204.10957
Local maxima and minima, or extremal events, in experimental time series can be used as a coarse summary to characterize data. However, the discrete sampling in recording experimental measurements suggests uncertainty on the true timing of extrema du
Externí odkaz:
http://arxiv.org/abs/2203.09552
Extending combinatorial regulatory network modeling to include activity control and decay modulation
Autor:
Cummins, Bree, Gameiro, Marcio, Gedeon, Tomas, Kepley, Shane, Mischaikow, Konstantin, Zhang, Lun
Understanding how the structure of within-system interactions affects the dynamics of the system is important in many areas of science. We extend a network dynamics modeling platform DSGRN, which combinatorializes both dynamics and parameter space to
Externí odkaz:
http://arxiv.org/abs/2111.01399
Research shows that gene duplication followed by either repurposing or removal of duplicated genes is an important contributor to evolution of gene and protein interaction networks. We aim to identify which characteristics of a network can arise thro
Externí odkaz:
http://arxiv.org/abs/2107.12352
Publikováno v:
J. Math. Biol. 84, 2 (2022)
Transcription and translation retrieve and operationalize gene encoded information in cells. These processes are not instantaneous and incur significant delays. In this paper we study Goodwin models of both inducible and repressible operons with stat
Externí odkaz:
http://arxiv.org/abs/2106.06628
Publikováno v:
In Medical Hypotheses May 2024 186
Publikováno v:
In Journal of Theoretical Biology 7 March 2024 580