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pro vyhledávání: '"Gebler, J."'
Publikováno v:
In Procedia Engineering 2012 42:1219-1228
Akademický článek
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Akademický článek
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An automated RP/RP 2D nanoLC/MS method was developed and applied for E. coli digest analysis. Even though the first and second dimensions were both carried out with reversed phase (RP), the separation was performed with a high degree of orthogonality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::96c43cc74d17eb6ebd909f5bedd6211d
https://europepmc.org/articles/PMC2291896/
https://europepmc.org/articles/PMC2291896/
Autor:
Li, G., Golick, D., Dyson, B., Silva, J. C., Liu, H., Vissers, J. P. C., Gebler, J. C., Gorenstein, M. V., Geromanos, S. J.
A novel, “Ion Accounting” algorithm has been developed for protein identification using time-resolved, LC-MSE data from 1D and 2D LC-MS experiments. The data from a 1D LC-MS analysis generate a series of precursor-product tables that are initiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::87285081b220d48eb6db7c0f46e77112
https://europepmc.org/articles/PMC2292061/
https://europepmc.org/articles/PMC2292061/
Mass spectrometry–based biomarker discovery in bio-fluids produces a list of candidate proteins that must be verified and quantified in a large number of samples before a candidate becomes a useful diagnostic, prognostic, or pharmacodynamic marker.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::1190f111559fa12976f92b96b77c47c0
https://europepmc.org/articles/PMC2292030/
https://europepmc.org/articles/PMC2292030/
The reversible phophorylation of serine, threonine, and tyrosine is one of the most important post-translational modifications involved in various cellular functions. Identification of phophorylation sites by mass spectrometry is challenging due to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::a34ea4835767c06f4df80b94ed71df7a
https://europepmc.org/articles/PMC2291822/
https://europepmc.org/articles/PMC2291822/
The identification of phosphorylated peptides by LC-MS is a challenging task. It is in part due to the relative low abundance of phosphopeptides; and their low ionization efficiency in positive ESI-MS ionization mode. The problem is further exacerbat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::9cfcf8c21c8c607b5e77680bc44b1119
https://europepmc.org/articles/PMC2292057/
https://europepmc.org/articles/PMC2292057/
Phosphorylation is an important regulator of cell function in eukaryotes. This post-translational modification can alter protein localization, regulate protein function, and stabilize and mediate their interactions. Due to their associated negative c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::e267123d5549340a9de35bbf14e97b57
https://europepmc.org/articles/PMC2292064/
https://europepmc.org/articles/PMC2292064/
Recombinant monoclonal antibodies (MAb) comprise a significant proportion of biopharmaceuticals used in diagnostic and therapeutic applications. Although the general structural features of monoclonal antibody such as disulfide bond patterns have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::afc20065b839ad81eeb877f3ea495624
https://europepmc.org/articles/PMC2291911/
https://europepmc.org/articles/PMC2291911/