Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Geard, Nicholas"'
Autor:
Harris, Thomas, Jayasundara, Pavithra, Ragonnet, Romain, Trauer, James, Geard, Nicholas, Zachreson, Cameron
Social contact patterns are key drivers of infectious disease transmission. During the COVID-19 pandemic, differences between pre-COVID and COVID-era contact rates were widely attributed to non-pharmaceutical interventions such as lockdowns. However,
Externí odkaz:
http://arxiv.org/abs/2406.01639
Autor:
Zachreson, Cameron, Tobin, Ruarai, Walker, Camelia, Conway, Eamon, Shearer, Freya M, McVernon, Jodie, Geard, Nicholas
Residential aged-care facilities (RACFs, also called long-term care facilities, aged care homes, or nursing homes) have elevated risks of respiratory infection outbreaks and associated disease burden. During the COVID-19 pandemic, social isolation po
Externí odkaz:
http://arxiv.org/abs/2401.01371
Antibodies, a prominent class of approved biologics, play a crucial role in detecting foreign antigens. The effectiveness of antigen neutralisation and elimination hinges upon the strength, sensitivity, and specificity of the paratope-epitope interac
Externí odkaz:
http://arxiv.org/abs/2309.01122
Early estimates of the transmission properties of a newly emerged pathogen are critical to an effective public health response, and are often based on limited outbreak data. Here, we use simulations to investigate a potential source of bias in such e
Externí odkaz:
http://arxiv.org/abs/2211.08673
Publikováno v:
Bioinformatics 38.22 (2022) 5026-5032
Survival risk prediction using gene expression data is important in making treatment decisions in cancer. Standard neural network (NN) survival analysis models are black boxes with lack of interpretability. More interpretable visible neural network (
Externí odkaz:
http://arxiv.org/abs/2202.00882
Multi-strain pathogens such as Group A Streptococcus, Streptococcus pneumoniae, and Staphylococcus aureus cause millions of infections each year with a substantial health burden. Control of multi-strain pathogens can be complicated by the high strain
Externí odkaz:
http://arxiv.org/abs/2111.07762
Autor:
Chisholm, Rebecca H., Lacey, Jake A., Kokko, Jan, Campbell, Patricia T., McDonald, Malcolm I., Corander, Jukka, Davies, Mark R., Tong, Steven Y. C., McVernon, Jodie, Geard, Nicholas
The bacterium Group A Streptococcus (Streptococcus pyogenes, GAS) is a human-specific pathogen and a major cause of global morbidity and mortality. Despite decades of research our knowledge of GAS infection and immunity is incomplete, hampering vacci
Externí odkaz:
http://arxiv.org/abs/2111.06498
Publikováno v:
In Computers in Biology and Medicine November 2024 182
Autor:
Zachreson, Cameron, Shearer, Freya M., Price, David J., Lydeamore, Michael J., McVernon, Jodie, McCaw, James, Geard, Nicholas
In controlling transmission of COVID-19, the effectiveness of border quarantine strategies is a key concern for jurisdictions in which the local prevalence of disease and immunity is low. In settings like this such as China, Australia, and New Zealan
Externí odkaz:
http://arxiv.org/abs/2109.12799
Autor:
Zachreson, Cameron, Mitchell, Lewis, Lydeamore, Michael J., Rebuli, Nicolas, Tomko, Martin, Geard, Nicholas
COVID-19 is highly transmissible and containing outbreaks requires a rapid and effective response. Because infection may be spread by people who are pre-symptomatic or asymptomatic, substantial undetected transmission is likely to occur before clinic
Externí odkaz:
http://arxiv.org/abs/2008.06193