Zobrazeno 1 - 10
of 1 956
pro vyhledávání: '"Ge GAO"'
Autor:
Weixian Kong, Yu Liu, Pu Ai, Yong Bi, Chaoguang Wei, Xiaoyang Guo, Zhenyu Cai, Ge Gao, Peng Hu, Jialin Zheng, Jianhui Liu, Minfeng Huo, Yuting Guan, Qihui Wu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract The characteristic neuropathology of Parkinson’s disease (PD) involves the abnormal accumulation of phosphorylated α-synuclein (αSyn), as well as a significant decrease in neuromelanin (NM) levels within dopamine neurons (DaNs). Unlike
Externí odkaz:
https://doaj.org/article/2d0d443d8b534c028c50fac8a49136fa
Autor:
Jing Ren, Chao Wu, Mengxia Zeng, Mingqin Qu, Ge Gao, Ning Chen, Jingjing Yue, Yuwen Jiang, Tongfei Zhao, Na Xiang, Fangang Meng, Ling-ling Lu
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract To investigate physiological function of α-synuclein is important for understanding its pathophysiological mechanism in synucleinopathies including Parkinson’s disease. Employing knockout mice, we found that Snac/α-synuclein deletion ind
Externí odkaz:
https://doaj.org/article/280939f9b7474a71acff6b680305c693
Autor:
Wei Li, Yongsheng Wang, Anwen Xiong, Ge Gao, Zhengbo Song, Yiping Zhang, Dingzhi Huang, Feng Ye, Qiming Wang, Zhihui Li, Jiaye Liu, Chunwei Xu, Yinghui Sun, Xijie Liu, Fei Zhou, Caicun Zhou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Oncogenic RET alteration is an important, tissue-agnostic therapeutic target across diverse cancers. We conducted a first-in-human phase 1 study on SY-5007, a potent and selective RET inhibitor, in patients with RET-altered solid tumors. Pri
Externí odkaz:
https://doaj.org/article/9b3ef713d33944be9c3cacf900624792
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Controllable droplet propulsion on solid surfaces plays a crucial role in various technologies. Many actuating methods have been developed; however, there are still some limitations in terms of the introduction of additives, the versatilitie
Externí odkaz:
https://doaj.org/article/756e4d760e8a4bdcb27c8c43234eb550
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Zearalenone (ZEA) is a mycotoxin produced by Fusarium fungi that has been shown to have adverse effects on human and animal health, particularly on the fertility of females. As a saponin derived from the medicinal plant Centella asiatica, as
Externí odkaz:
https://doaj.org/article/78913dd10ecf469c9bc4b9b51e505d1e
Autor:
Dan Zhou, Rao Cheng, Yanfeng Yao, Gan Zhang, Xin Li, Bingjie Wang, Yong Wang, Feiyang Yu, Shangyu Yang, Hang Liu, Ge Gao, Yun Peng, Miaoyu Chen, Zengqin Deng, Haiyan Zhao
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Nipah virus (NiV) is a zoonotic emergent paramyxovirus that can cause severe encephalitis and respiratory infections in humans, with a high fatality rate ranging from 40% to 75%. Currently, there are no approved human vaccines or antiviral d
Externí odkaz:
https://doaj.org/article/e542eaba701d49ee848e3d55429ec208
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Mendelian randomization (MR) studies have an advantage over conventional observational studies when studying the causal effect of lifestyle-related risk factors on back pain. However, given the heterogeneous design of existing MR
Externí odkaz:
https://doaj.org/article/932b5d2d0025432f937e4a6d953f3a20
Autor:
Zhiqian Ouyang, Xiuqing Fu, Zhibo Zhong, Ruxiao Bai, Qianzhe Cheng, Ge Gao, Meng Li, Haolun Zhang, Yaben Zhang
Publikováno v:
Plant Methods, Vol 20, Iss 1, Pp 1-19 (2024)
Abstract Background Since traditional germination test methods have drawbacks such as slow efficiency, proneness to error, and damage to seeds, a non-destructive testing method is proposed for full-process germination of radish seeds, which improves
Externí odkaz:
https://doaj.org/article/9c41d3184cca4e0790526774880a8bc2
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101286- (2024)
Vascular tissue engineering faces significant challenges in creating in vitro vascular disease models, implantable vascular grafts, and vascularized tissue/organ constructs due to limitations in manufacturing precision, structural complexity, replica
Externí odkaz:
https://doaj.org/article/764aa7bb1b61433b8fde17e9c6a6860d
Publikováno v:
Geomatics, Natural Hazards & Risk, Vol 15, Iss 1 (2024)
In today’s era of unprecedented climate change, research on environmental changes and natural disasters remains crucial. Locust plagues, among the most devastating agricultural disasters, had a profound impact on ancient China, especially during th
Externí odkaz:
https://doaj.org/article/2e05208df1434f718866aba4143bd150