Organization and maintenance of Drosophila telomeres: the roles of terminin and non-terminin proteins

Autor: Gd, Raffa, Giovanni Cenci, Ciapponi L, Gatti M

Publikováno v: Scopus-Elsevier
Tsitologiia
Tsitologiia, 2013, 55 (3), pp.204-8
Europe PubMed Central
Tsitologiia (2013).
info:cnr-pdr/source/autori:Raffa GD, Cenci G, Ciapponi L, Gatti M./titolo:Organization and maintenance of Drosophila telomeres: the roles of terminin and non-terminin proteins./doi:/rivista:Tsitologiia/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume

Drosophila telomeres are elongated by occasional transposition of specialized retroelements rather than telomerase activity, and are assembled independently of the sequence of the DNA termini. Drosophila telomeres are capped by terminin, a complex fo

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Maintaining Telomeres without Telomerase in Drosophila : Novel Mechanisms and Rapid Evolution to Save a Genus.

Autor: Cacchione S; Department of Biology and Biotechnology, Sapienza University of Rome, 00185 Rome, Italy., Cenci G; Department of Biology and Biotechnology, Sapienza University of Rome, 00185 Rome, Italy.; Fondazione Cenci Bolognetti, Istituto Pasteur, 00161 Roma, Italy., Dion-Côté AM; Département de Biologie, Université de Moncton, Moncton, New Brunswick E1A 3E9, Canada., Barbash DA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA., Raffa GD; Department of Biology and Biotechnology, Sapienza University of Rome, 00185 Rome, Italy graziadaniela.raffa@uniroma1.it.

Publikováno v: Cold Spring Harbor perspectives in biology [Cold Spring Harb Perspect Biol] 2024 Dec 18. Date of Electronic Publication: 2024 Dec 18.

TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.

Autor: Chen L; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.; Cancer Signaling and Epigenetics Program and Cancer Epigenetics Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Roake CM; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA., Maccallini P; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Bavasso F; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Dehghannasiri R; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA., Santonicola P; Institute of Biosciences and BioResources, IBBR, CNR, Naples, Italy., Mendoza-Ferreira N; Institute of Human Genetics, Center for Molecular Medicine Cologne, Institute for Genetics, University of Cologne, 50931 Cologne, Germany., Scatolini L; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Rizzuti L; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Esposito A; Institute of Genetics and Biophysics, IGB-ABT, CNR, Naples, Italy., Gallotta I; Institute of Genetics and Biophysics, IGB-ABT, CNR, Naples, Italy., Francia S; IFOM-The FIRC Institute of Molecular Oncology, Milan, Italy.; Istituto di Genetica Molecolare, CNR-Consiglio Nazionale delle Ricerche, Pavia, Italy., Cacchione S; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Galati A; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Palumbo V; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy., Kobin MA; Cancer Signaling and Epigenetics Program and Cancer Epigenetics Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Tartaglia GG; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy.; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome 00161, Italy.; Center for Human Technology, Fondazione Istituto Italiano di Tecnologia (IIT), Genoa 16152, Italy., Colantoni A; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy.; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome 00161, Italy.; Center for Human Technology, Fondazione Istituto Italiano di Tecnologia (IIT), Genoa 16152, Italy., Proietti G; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome 00161, Italy.; Center for Human Technology, Fondazione Istituto Italiano di Tecnologia (IIT), Genoa 16152, Italy., Wu Y; Cancer Signaling and Epigenetics Program and Cancer Epigenetics Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA., Hammerschmidt M; Institute for Zoology, Developmental Biology, University of Cologne, 50674 Cologne, Germany., De Pittà C; Department of Biology, University of Padova, Padua, Italy., Sales G; Department of Biology, University of Padova, Padua, Italy., Salzman J; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA., Pellizzoni L; Center for Motor Neuron Biology and Disease, Columbia University, NY 10032, USA.; Department of Pathology and Cell Biology, Columbia University, NY 10032, USA.; Department of Neurology, Columbia University, NY 10032, USA., Wirth B; Institute of Human Genetics, Center for Molecular Medicine Cologne, Institute for Genetics, University of Cologne, 50931 Cologne, Germany.; Center for Rare Diseases, University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany., Di Schiavi E; Institute of Biosciences and BioResources, IBBR, CNR, Naples, Italy.; Institute of Genetics and Biophysics, IGB-ABT, CNR, Naples, Italy., Gatti M; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy.; Istituto di Biologia e Patologia Molecolari (IBPM) del CNR, Rome, Italy., Artandi SE; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA., Raffa GD; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy.

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The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening.

Autor: Galati A; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Scatolini L; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Micheli E; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Bavasso F; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Cicconi A; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Maccallini P; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Chen L; Cancer Signaling and Epigenetics Program-Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA., Roake CM; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Schoeftner S; Dipartimento di Scienze della Vita, Università degli studi di Trieste, Italy., Artandi SE; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Gatti M; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy.; Istituto di Biologia e Patologia Molecolari del CNR, Roma, Italy., Cacchione S; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy., Raffa GD; Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Italy.

Publikováno v: FEBS letters [FEBS Lett] 2022 Jan; Vol. 596 (1), pp. 42-52. Date of Electronic Publication: 2021 Dec 05.

Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements.

Autor: Cacchione S; Department of Biology and Biotechnology, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Roma, Italy. Electronic address: stefano.cacchione@uniroma1.it., Cenci G; Department of Biology and Biotechnology, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Roma, Italy; Fondazione Cenci Bolognetti, Istituto Pasteur, Rome, Italy. Electronic address: giovanni.cenci@uniroma1.it., Raffa GD; Department of Biology and Biotechnology, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Roma, Italy. Electronic address: graziadaniela.raffa@uniroma1.it.

Publikováno v: Journal of molecular biology [J Mol Biol] 2020 Jul 10; Vol. 432 (15), pp. 4305-4321. Date of Electronic Publication: 2020 Jun 05.