Identification of new human CYP2C19 alleles (CYP2C19*6 and CYP2C19*2B) in a Caucasian poor metabolizer of mephenytoin

Autor: Gc, Ibeanu, Ja, Goldstein, Meyer U, Simone BENHAMOU, Bouchardy C, Dayer P, Bi, Ghanayem, Blaisdell J

Publikováno v: Europe PubMed Central

A genetic polymorphism in the metabolism of the anticonvulsant drug S-mephenytoin has been attributed to defective CYP2C19 alleles. This genetic polymorphism displays large interracial differences with the poor metabolizer (PM) phenotype representing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2100876eca9479dd44084ac991c75fa
https://pubmed.ncbi.nlm.nih.gov/9732415

B355252 Suppresses LPS-Induced Neuroinflammation in the Mouse Brain.

Autor: He Q; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute and Technology Enterprise (BRITE), College of Health and Sciences, North Carolina Central University, Durham, NC 27707, USA., Qi Q; Human Vaccine Institute, Department of Surgery, Duke University Medical Center, Durham, NC 27707, USA., Ibeanu GC; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute and Technology Enterprise (BRITE), College of Health and Sciences, North Carolina Central University, Durham, NC 27707, USA., Li PA; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute and Technology Enterprise (BRITE), College of Health and Sciences, North Carolina Central University, Durham, NC 27707, USA.

Publikováno v: Brain sciences [Brain Sci] 2024 May 07; Vol. 14 (5). Date of Electronic Publication: 2024 May 07.

Emergency medicine: magnesium sulphate injections and their pharmaceutical quality concerns.

Autor: Oli AN; Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Agulu, Anambra state, Nigeria., Nwankwo EJ; Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Agulu, Anambra state, Nigeria., Umeyor CE; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Agulu, Awka, Anambra State, Nigeria., Umeh US; Department of Ear, Nose and Throat (ENT), Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria., Okoyeh JN; Department of Biology and Clinical Laboratory Science, Division of Arts and Sciences, Neumann University, One Neumann Drive, Aston, PA, 19014-1298, USA., Ofomata CM; Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Agulu, Awka, P.M.B 5025, Anambra State, Nigeria., Okoro CC; Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra state, Nigeria., Otakagu EC; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Agulu, Awka, Anambra State, Nigeria., Afunwa RA; Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, ChukwuemekaOdumegwuOjukwu University, Igbariam Campus, Anambra state, Nigeria., Ibeanu GC; Department of Pharmaceutical Science, North Carolina Central University, Durham, NC, 27707, USA.

Publikováno v: Heliyon [Heliyon] 2021 May 22; Vol. 7 (5), pp. e07099. Date of Electronic Publication: 2021 May 22 (Print Publication: 2021).

Analysis of Gene Expression and Neuronal Phenotype in Neuroscreen-1 (NS-1) Cells.

Autor: Pokharel S; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina, United States of America., Lee CH; School of Dentistry, Medical College of Virginia, Richmond, Virginia, United States of America., Gilyazova N; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina, United States of America., Ibeanu GC; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina, United States of America.; Department of Pharmaceutical Science, North Carolina Central University, Durham, North Carolina United States of America.

Publikováno v: International journal of biomedical investigation [Int J Biomed Investig] 2018 Sep-Dec; Vol. 1 (3). Date of Electronic Publication: 2018 Dec 17.

Transcriptional Response of Selenopolypeptide Genes and Selenocysteine Biosynthesis Machinery Genes in Escherichia coli during Selenite Reduction.

Autor: Tetteh AY; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute & Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA ; Department of Biochemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Sun KH; School of Geography and Geosciences, University of St Andrews, St Andrews, Fife KY16 9AX, UK., Hung CY; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute & Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA., Kittur FS; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute & Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA., Ibeanu GC; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute & Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA., Williams D; Department of Biology, North Carolina Central University, Durham, NC 27707, USA., Xie J; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute & Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA.

Publikováno v: International journal of microbiology [Int J Microbiol] 2014; Vol. 2014, pp. 394835. Date of Electronic Publication: 2014 Apr 15.