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Mutator dynamics in sexual and asexual experimental populations of yeast

Autor: Gazzara Matthew R, Raynes Yevgeniy, Sniegowski Paul D

Publikováno v: BMC Evolutionary Biology, Vol 11, Iss 1, p 158 (2011)

Abstract Background In asexual populations, mutators may be expected to hitchhike with associated beneficial mutations. In sexual populations, recombination is predicted to erode such associations, inhibiting mutator hitchhiking. To investigate the e

Externí odkaz: https://doaj.org/article/bdb9013567b04741a7004563f0535b0f

Enhanced Integrated Gradients: improving interpretability of deep learning models using splicing codes as a case study.

Autor: Jha A; Department of Computer and Information Science, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, USA., K Aicher J; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA., R Gazzara M; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA., Singh D; Department of Computer and Information Science, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, USA., Barash Y; Department of Computer and Information Science, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, USA. yosephb@upenn.edu.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA. yosephb@upenn.edu.

Publikováno v: Genome biology [Genome Biol] 2020 Jun 19; Vol. 21 (1), pp. 149. Date of Electronic Publication: 2020 Jun 19.