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Ultrasensitive quantification of cardiac troponin I by a Single Molecule Counting method: analytical validation and biological features

Autor: Garcia-Osuna, A, Gaze, D, Grau-Agrarnunt, M, Morris, T, Telha, C, Bartolome, A, Bishop, JJ, Monsalve, L, Livingston, R, Estis, J, Nolan, N, Sandlund, J, Ordonez-Llanos, J

Publikováno v: CLINICA CHIMICA ACTA
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Aim: To evaluate analytical and biological characteristics of the Singulex Clarity (R) cTnI assay, based upon Single Molecule Counting technology. Methods: Assay's analytical sensitivity, precision, linearity, hook effect, cross-reactivity or interfe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::fd06d50ddca69e512d60ca7521ce9bca
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3259

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The mediation of coronary calcification in the association between risk scores and cardiac troponin T elevation in healthy adults: Is atherosclerosis a good prognostic precursor of coronary disease?

Autor: Lazzarino, AI, Hamer, M, Carvalho, L, Gaze, D, Collinson, P, Steptoe, A

Publikováno v: Preventive Medicine. 77:150-154

BACKGROUND: Conventional cardiac risk scores may not be completely accurate in predicting acute events because they only include factors associated with atherosclerosis, considered as the fundamental precursor of cardiovascular disease. In UK in 2006

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::010052c75d1298ba3dc3a07a0c1c3df2

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Evaluation of the European Society of Cardiology recommended rapid diagnostic algorithms in a challenging low risk cohort

Autor: Collinson, P, Gaze, D, Goodacre, S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2ef1ed9cc4b5bd1983c5d858ae4af93a

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Heart Fatty Acid Binding Protein for the Diagnosis of Myocardial Ischemia and Infarction

Autor: Collinson, PO, Hersey, J, Bray, R, Gaze, D, Lim, P, Firoozi, S, Ntalianis, A, Boa, F, Prasad, A

Objective\ud To establish the analytical performance of a heart fatty acid binding protein (HFABP) method suitable for routine clinical use and examine its role for the diagnosis of myocardial ischemia and myocardial infarction.\ud \ud Methods\ud Ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3035477b4c64060d543cd30d1b8386b5

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Effects of nebivolol on biomarkers in elderly patients with heart failure

Autor: Taneja, AK, Gaze, D, Coats, AJS, Dumitrascu, D, Spinarova, L, Collinson, P, Roughton, M, Flather, MD, SENIORS Investigators

BACKGROUND: Heart failure activates neurohormones, and elevated levels of brain natriuretic peptide (BNP) are associated with adverse outcomes. The SENIORS trial showed that nebivolol, a highly selective beta-1 antagonist with vasodilating properties

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1d27190cd9f13358eba3a7ad3775acd8

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Cardiac troponins in intensive care

Autor: Collinson, P, Gaze, D

Publikováno v: Critical Care

The cardiac troponins are integral components of the myofibrillary apparatus and they regulate muscle contraction. The measurement of cardiac troponins has replaced other biomarkers for the specific detection of myocardial necrosis and for the diagno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4efaf016f351e772c6eac520ac0d018e
http://europepmc.org/articles/PMC1269477

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