Robust hepatitis B vaccine-reactive T cell responses in failed humoral immunity

Autor: Awad, Gounwa ¹, Roch, Toralf ^{1, 2}, Stervbo, Ulrik ¹, Kaliszczyk, Sviatlana ^{1, 2}, Stittrich, Anna ^{2, 3}, Hörstrup, Jan ⁴, Cinkilic, Ocan ⁵, Appel, Heiner ⁶, Natrus, Larysa ⁷, Gayova, Ludmila ⁷, Seibert, Felix ¹, Bauer, Frederic ¹, Westhoff, Timm ¹, Nienen, Mikalai ^{2, 3, 8, 9}, Babel, Nina ^{1, 2, 9, ∗}

Publikováno v: In Molecular Therapy - Methods & Clinical Development 11 June 2021 21:288-298

The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains

Autor: Nienen, Mikalai, Stervbo, Ulrik, Mölder, Felix, Kaliszczyk, Sviatlana, Kuchenbecker, Leon, Gayova, Ludmila, Schweiger, Brunhilde, Jürchott, Karsten, Hecht, Jochen, Neumann, Avidan, Rahmann, Sven, Westhoff, Timm, Reinke, Petra, Thiel, Andreas, Babel, Nina

Publikováno v: Front. Immunol. 10:593 (2019)
Frontiers in Immunology

Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing antibodies against close viral strains might impair antibody formation against previously unseen strains–a process called original antigenic sin. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00759e67f34ed714760ec89fc67c250d
https://www.ncbi.nlm.nih.gov/pubmed/31019503

The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains.

Autor: Nienen M; Institute for Medical Immunology, Charité University Medicine Berlin, Berlin, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin, Germany., Stervbo U; Center for Translational Medicine, Immunology and Transplantation, Marien Hospital Herne, Ruhr University Bochum, Herne, Germany., Mölder F; Genome Informatics, Institute of Human Genetics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Kaliszczyk S; Center for Translational Medicine, Immunology and Transplantation, Marien Hospital Herne, Ruhr University Bochum, Herne, Germany., Kuchenbecker L; Applied Bioinformatics, Tübingen University, Tübingen, Germany., Gayova L; Bogomolets National Medical University, Kyiv, Ukraine., Schweiger B; Robert-Koch Institute, Berlin, Germany., Jürchott K; Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany., Hecht J; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Neumann AU; Institute of Environmental Medicine, German Research Center for Environmental Health, Helmholtz Zentrum München, Augsburg, Germany., Rahmann S; Genome Informatics, Institute of Human Genetics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Westhoff T; Department of Internal Medicine, Marien Hospital Herne, Ruhr University Bochum, Herne, Germany., Reinke P; Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany.; Department of Nephrology and Intensive Care, Charité University Medicine Berlin, Berlin, Germany., Thiel A; Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany., Babel N; Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany.; Center for Translational Medicine, Immunology and Transplantation, Marien Hospital Herne, Ruhr University Bochum, Herne, Germany.; Department of Nephrology and Intensive Care, Charité University Medicine Berlin, Berlin, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2019 Apr 04; Vol. 10, pp. 593. Date of Electronic Publication: 2019 Apr 04 (Print Publication: 2019).