Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gayle N. Shibao"'
Autor:
Richard M. Wright, Mari E. Weyman, Mehdi A. Fini, Gayle N. Shibao, Hillary Fitzgerald, Nancy D. Elkins, Janice Tiao, Sophie Gibbings
Publikováno v:
Gibbings, S, Elkins, N D, Fitzgerald, H, Tiao, J, Weyman, M E, Shibao, G, Fini, M A & Wright, R M 2011, ' Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1 alpha ', Journal of Biological Chemistry, vol. 286, no. 2, pp. 961-975 . https://doi.org/10.1074/jbc.M110.150847
The protective effects of pharmacological inhibitors of xanthine oxidoreductase (XOR) have implicated XOR in many inflammatory diseases. Nonetheless, the role played by XOR during inflammation is poorly understood. We previously observed that inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04ea2758938bc72fa487e53e47b90d8
https://doi.org/10.1074/jbc.m110.150847
https://doi.org/10.1074/jbc.m110.150847
Autor:
Young Mook Lee, Brooks M. Hybertson, Gayle N. Shibao, Okyong J. Cho, John E. Repine, Jin H. Chung, Brian N. Hansen, Mehdi A. Fini, Jenny D. Allard
Publikováno v:
Experimental Lung Research. 31:283-294
Intrapulmonary administration of bacterial lipopolysaccharide (LPS) induces a well-characterized lung inflammatory response involving alveolar macrophage activation, proinflammatory cytokine elaboration, and neutrophil influx. Vitamin E, a lipophilic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2709950e1b1db25dd901ee33f730474
https://doi.org/10.1080/01902140590918560
https://doi.org/10.1080/01902140590918560
Publikováno v:
Archives of biochemistry and biophysics. 348(1)
Hypoxia increases the activity of xanthine oxidase (XO) and its precursor, xanthine dehydrogenase (XDH), but the mechanism of regulation is unclear. In hypoxic Swiss 3T3 cells, an early (0–24 h) cycloheximide-insensitive increase in XO-XDH activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77debce0f1d3f7dc29a5c0c38e24ad28
https://pubmed.ncbi.nlm.nih.gov/9390187
https://pubmed.ncbi.nlm.nih.gov/9390187
Autor:
Irene R. Willingham, John E. Repine, Gayle N. Shibao, Glenn W. Kindt, Lance S. Terada, David M. Guidot
Publikováno v:
Inflammation. 16(1)
Exposure to recombinant human tumor necrosis factor-alpha (TNF-alpha) or calcium ionophore (A23187) for 4 h increased (P less than 0.05) lactate dehydrogenase (LDH) release from cultured bovine brain endothelial cells (EC). In contrast, treatment wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4ae4bd9cbf96c6befd1eb981c58bca
https://pubmed.ncbi.nlm.nih.gov/1544679
https://pubmed.ncbi.nlm.nih.gov/1544679