Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gayle, Grigson"'
Autor:
Paul A. Godley, Karla Morris, W. Kimryn Rathmell, Dominic T. Moore, Daniel J. George, Gayle Grigson, Raj S. Pruthi, Jeffrey M. Crane, Eric Wallen, William Y. Kim, Catharine Watkins, Young E. Whang, Andrew J. Armstrong
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 31:82-86
Objectives Epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases may be involved in activation of androgen receptor and progression of prostate cancer. They represent potential therapeutic targets in prostate cancer. Lapatinib is an oral
Autor:
Eric Wallen, Young E. Whang, Catharine Watkins, Paul A. Godley, Raj S. Pruthi, W. Kimryn Rathmell, Maria Q. Baggstrom, Julian G. Rosenman, William Y. Kim, Lav K. Goyal, Gayle Grigson
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 29:608-613
Background Patients with locally advanced or organ confined, high risk, prostate cancer are at significant risk of having disease recurrence despite definitive local therapy. We evaluated the 2-year progression-free survival of subjects treated with
Autor:
Angela B. Smith, Raj S. Pruthi, Young E. Whang, Gayle Grigson, Julia R. Fielding, Samuel A. Heathcote, Eric Wallen, Paul A. Godley, W. Kim Rathmell, William Y. Kim, Matthew E. Nielsen, Heather Schultz
Publikováno v:
BJU International. 106:349-354
Study Type – Therapy (cohort) Level of Evidence 2b OBJECTIVE To evaluate the clinicopathological efficacy of neoadjuvant erlotinib (an epidermal growth factor receptor, EGFR, inhibitor) for invasive bladder cancer in patients undergoing radical cys
Autor:
W. Kimryn Rathmell, Christine B. Marino, T. Richmond, Jared Gollob, Catharine Watkins, Gayle Grigson, Lin Gu, Bercedis L. Peterson, Elizabeth K. Miller, John J. Wright
Publikováno v:
Journal of Clinical Oncology. 25:3288-3295
Purpose We undertook this study to determine the activity and tolerability of sorafenib administered with interferon alfa-2b (IFN-α-2b) as first- or second-line therapy in metastatic renal cell cancer (RCC). Patients and Methods Between November 200
Autor:
Raj S. Pruthi, Cathy Watkins, Culley C. Carson, J. Eric Derksen, Eric Wallen, Gayle Grigson, Dominic T. Moore
Publikováno v:
Clinical Cancer Research. 12:2172-2177
Objectives: Recent evidence has shown that cyclooxygenase-2 (COX-2) inhibitors have potent antitumor activity in prostate cancer both in vitro and in vivo. However, human trials are absent. This study evaluated the efficacy of the COX-2 inhibitor cel
Autor:
Raj S, Pruthi, Matthew, Nielsen, Samuel, Heathcote, Eric M, Wallen, W Kim, Rathmell, Paul, Godley, Young, Whang, Julia, Fielding, Heather, Schultz, Gayle, Grigson, Angela, Smith, William, Kim
Publikováno v:
BJU international. 106(3)
To evaluate the clinicopathological efficacy of neoadjuvant erlotinib (an epidermal growth factor receptor, EGFR, inhibitor) for invasive bladder cancer in patients undergoing radical cystectomy (RC) as despite definitive surgical therapy, only half
Autor:
Young E. Whang, C. Lance Cowey, William Y. Kim, Dominic Moore, Gayle Grigson, Matthew E. Nielsen, Cathy Watkins, Jeffrey M. Crane, Keith V. Nance, Paul A. Godley, Chirag Amin, Eric Wallen, Mark Jalkut, Julia R. Fielding, W. Kimryn Rathmell, Raj S. Pruthi
Purpose The multitargeted tyrosine kinase inhibitor sorafenib is used for the treatment of advanced-stage renal cell carcinoma. However, the safety and efficacy of this agent have yet to be evaluated in the preoperative period, where there may be pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5bf22495e8619a5f7cb8de436609da
Publikováno v:
Journal of Clinical Oncology. 26:11076-11076
11076 Background: Despite surgical therapy, only 50% of patients undergoing radical cystectomy for transitional cell carcinoma (TCC) of the bladder will experience long-term disease-free survival. ...
Autor:
Cathy Watkins, Karla Morris, Jeffrey M. Crane, Cassandra Moore, Andrew J. Armstrong, Wendy Kimryn Rathmell, Daniel J. George, Gayle Grigson, Young E. Whang, Paul A. Godley
Publikováno v:
Journal of Clinical Oncology. 26:16037-16037
16037 Background: Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) tyrosine kinases represent potential targets in prostate cancer. HER2 promotes progression of prostate cancer to the hormone refractory stag
Autor:
John J. Wright, Cathy Watkins, J. Jones, Wendy Kimryn Rathmell, Jared Gollob, Bercedis L. Peterson, Gayle Grigson, T. Richmond
Publikováno v:
Journal of Clinical Oncology. 24:4538-4538
4538 Background: Sorafenib is a VEGFR/PDGFR-β/Raf inhibitor that improves PFS in metastatic RCC with a RR of 2%. IFN-α improves OS in RCC with a RR of ≈10%. Methods: Based on the activity of sorafenib and IFN-α in RCC, a phase II combination tri