Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gayatri Subramanian"'
Autor:
Gayatri Subramanian, Adam Hage, Friederike Feldmann, Abhilash I. Chiramel, Kristin L. McNally, Gail L. Sturdevant, Paul A. Beare, Sonja M. Best
Publikováno v:
Viruses, Vol 16, Iss 9, p 1377 (2024)
The unprecedented research effort associated with the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) included several extensive proteomic studies that identified host proteins that interact with individual viral gene produc
Externí odkaz:
https://doaj.org/article/b6f86d9456e7430c99d8646e2ca3fe4f
Autor:
Sukanya Chakravarty, Gayatri Subramanian, Sonam Popli, Manoj Veleeparambil, Shumin Fan, Ritu Chakravarti, Saurabh Chattopadhyay
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Many viruses activate cellular autophagy in infected cells to facilitate their replication. Recently, we identified an interferon (IFN)-stimulated gene (ISG) Tudor domain containing 7 (TDRD7), which inhibits viral replication by blocking aut
Externí odkaz:
https://doaj.org/article/d4bec7584bed4ff0b03ef12fe76a638e
Autor:
Karan Chawla, Gayatri Subramanian, Tia Rahman, Shumin Fan, Sukanya Chakravarty, Shreyas Gujja, Hayley Demchak, Ritu Chakravarti, Saurabh Chattopadhyay
Publikováno v:
Immuno, Vol 2, Iss 1, Pp 153-169 (2022)
Virus-infected cells trigger a robust innate immune response and facilitate virus replication. Here, we review the role of autophagy in virus infection, focusing on both pro-viral and anti-viral host responses using a select group of viruses. Autopha
Externí odkaz:
https://doaj.org/article/1f74a55d56424bca9358e4342511f0d3
Autor:
Reena Goswami, Gayatri Subramanian, Liliya Silayeva, Isabelle Newkirk, Deborah Doctor, Karan Chawla, Saurabh Chattopadhyay, Dhyan Chandra, Nageswararao Chilukuri, Venkaiah Betapudi
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The human genetic code encrypted in thousands of genes holds the secret for synthesis of proteins that drive all biological processes necessary for normal life and death. Though the genetic ciphering remains unchanged through generations, some genes
Externí odkaz:
https://doaj.org/article/da28ef60e1604343b7dff03876f58c0c
Autor:
Anna Glanz, Karan Chawla, Stephanie Fabry, Gayatri Subramanian, Julie Garcia, Bryanna Jay, Jacob Ciricillo, Ritu Chakravarti, R. Travis Taylor, Saurabh Chattopadhyay
Publikováno v:
Viruses, Vol 12, Iss 4, p 442 (2020)
Interferon (IFN) regulatory factor 3 (IRF3) is the key transcription factor for the induction of IFN and antiviral genes. The absence of antiviral genes in IRF3 deficiency leads to susceptibility to a wide range of viral infections. Previously, we un
Externí odkaz:
https://doaj.org/article/e0439adb3acb4a6482935578c80beff7
Autor:
Gayatri Subramanian, Teodora Kuzmanovic, Ying Zhang, Cara Beate Peter, Manoj Veleeparambil, Ritu Chakravarti, Ganes C Sen, Saurabh Chattopadhyay
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006877 (2018)
The interferon (IFN) system represents the first line of defense against a wide range of viruses. Virus infection rapidly triggers the transcriptional induction of IFN-β and IFN Stimulated Genes (ISGs), whose protein products act as viral restrictio
Externí odkaz:
https://doaj.org/article/ebaa662cbebb4bc98f8a1757fc9a5790
Publikováno v:
Bio-Protocol, Vol 6, Iss 22 (2016)
Interferon regulatory factor 3 (IRF3) is a transcription factor, which is critical for the antiviral response against a wide range of viruses (Hiscott, 2007; Ikushima et al., 2013). It gets activated in virus-infected cells via Toll like receptors (T
Externí odkaz:
https://doaj.org/article/bcf4b8f2ee6e48d992ea42e8f89494bf
Autor:
Sukanya Chakravarty, R. Travis Taylor, Sonam Popli, Gayatri Subramanian, Saurabh Chattopadhyay, Ritu Chakravarti
Publikováno v:
J Biol Chem
The interferon system is the first line of defense against virus infection. Recently, using a high-throughput genetic screen of a human interferon-stimulated gene short-hairpin RNA library, we identified a viral restriction factor, TDRD7 (Tudor domai
Publikováno v:
Journal of Global Sport Management. 5:308-319
Building on the literature on psychological distance and visual illusion, the authors examine whether visual exposure to sports team symbols affect distance performance, depending on whether the sy...
Autor:
Dean Walters, Sukanya Chakravarty, Saurabh Chattopadhyay, Shumin Fan, Gayatri Subramanian, Anna Glanz, Tia Rahman, Ritu Chakravarti, Karan Chawla
Publikováno v:
The Journal of Biological Chemistry
The ubiquitously expressed transcription factor interferon (IFN) regulatory factor 3 (IRF3) is critical for the induction of antiviral genes, e.g., type-I IFN. In addition to its transcriptional function, IRF3 also activates a nontranscriptional, pro