Výsledky vyhledávání - "Gayatri Sanku"

Akademický článek

Brugia malayi filarial helminth-derived extracellular vesicles suppress antigen presenting cell function and antigen-specific CD4+ T cell responses

Autor: Gayatri Sanku, Alessandra Ricciardi, Neelam R. Redekar, Paul Schaughency, Justin Lack, Pedro H. Gazzinelli-Guimaraes, Thomas B. Nutman

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionLive microfilariae (mf) and mf-derived extracellular vesicles (EVs) have been shown to modulate human antigen presenting cell (APC) function, most notably by suppressing the induction of IL-12 (and other pro-inflammatory cytokines) follow

Externí odkaz: https://doaj.org/article/9ab7703f2dbf4a49b45184bdbbfcad87

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Akademický článek

Latin American Challenges and Recommendations for Poly Adenosine Diphosphate Ribose Polymerase Inhibitor Treatment in Metastatic Castration Resistant Prostate Cancer: An Expert Overview

Autor: Rodolfo Borges dos Reis MD, PHD, José L. Aguilar-Ponce MD, Federico Cayol MD, MSc, Angela M. Jansen PhD, MHS, Ray Manneh K MD, MSc, Tomas R Merino MD, Gayatri Sanku PhD, MPH, Laura B. Vaca MD, Pedro Isaacsson Velho MD, Ernesto P. Korbenfeld MD

Publikováno v: Cancer Control, Vol 31 (2024)

In Latin America, prostate cancer is the third most common cancer overall and the most common in men, with the highest mortality rate of all cancers. In 2022, there were approximately 22,985 new prostate cancer cases and 61,056 deaths from prostate c

Externí odkaz: https://doaj.org/article/02d40ef4d4894cab8a0974095637a926

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Akademický článek

BRAF-Mutated Melanoma Journey in Latin America: Expert Recommendations From Diagnosis to Treatment

Autor: María A. Bravo-Garzón MD, MSc, Leticia Bornstein-Quevedo MD, MSc, Veridiana Pires de Camargo MD, Gayatri Sanku PhD, MPH, Angela Marie Jansen PhD, MHS, Mariana Petaccia de Macedo MD, PhD, Mariana Rico-Restrepo MD, Matías Chacón MD

Publikováno v: Cancer Control, Vol 31 (2024)

Objectives • Gather a panel of Latin American experts in testing and treating BRAF -melanoma. • Describe the current landscape of BRAF -mutated melanoma in Latin America. • Outline the current gaps in testing and recommend improvements for test

Externí odkaz: https://doaj.org/article/a6a5391faa3b4867bb9ff07e95fe0eae

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Akademický článek

Antigenic Determinants of SARS-CoV-2-Specific CD4+ T Cell Lines Reveals M Protein-Driven Dysregulation of Interferon Signaling

Autor: Pedro H. Gazzinelli-Guimaraes, Gayatri Sanku, Alessandro Sette, Daniela Weiskopf, Paul Schaughency, Justin Lack, Thomas B. Nutman

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

We generated CD4+ T cell lines (TCLs) reactive to either SARS-CoV-2 spike (S) or membrane (M) proteins from unexposed naïve T cells from six healthy donor volunteers to understand in fine detail whether the S and M structural proteins have intrinsic

Externí odkaz: https://doaj.org/article/e2ac6f2177db47bb95a4548c876e9233

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