Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gayathri N. Silva"'
Publikováno v:
Thalassemia Reports, Vol 13, Iss 1, Pp 51-69 (2023)
β-Thalassemia is an inherited hematological disorder that results from genetic changes in the β-globin gene, leading to the reduced or absent synthesis of β-globin. For several decades, the only curative treatment option for β-thalassemia has bee
Externí odkaz:
https://doaj.org/article/b7336f71dab64ae1b5742d3a971381a1
Autor:
Gowthami Mahendran, Oshadhi T. Jayasinghe, Dhanushika Thavakumaran, Gayan Mirihana Arachchilage, Gayathri N. Silva
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101276- (2022)
Precise regulation of gene expression is crucial for living cells to adapt for survival in diverse environmental conditions. Among the common cellular regulatory mechanisms, RNA-based regulators play a key role in all domains of life. Discovery of re
Externí odkaz:
https://doaj.org/article/82a88caa644e423c99331d6925d324a2
Autor:
Shansa Pranami E. Jayaweera, Sacheela Prasadi Wanigasinghe Kanakanamge, Dharshika Rajalingam, Gayathri N. Silva
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The proteasome is crucial for the degradation of intracellular proteins and plays an important role in mediating a number of cell survival and progression events by controlling the levels of key regulatory proteins such as cyclins and caspases in bot
Externí odkaz:
https://doaj.org/article/1539749653ac4a9da82be0000528dd75
Autor:
Brogan Yarzabek, Anita J Zaitouna, Eli Olson, Gayathri N Silva, Jie Geng, Aviva Geretz, Rasmi Thomas, Sujatha Krishnakumar, Daniel S Ramon, Malini Raghavan
Publikováno v:
eLife, Vol 7 (2018)
The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8+ T cells, inducing immunity against infections and cancers. Quality control mediated by peptide loading complex (PLC) components is expected to ens
Externí odkaz:
https://doaj.org/article/5d732d5c075a44ddaa544ca33c52941f
Autor:
Seerpatham Divyasorubini, Shyami Menaka Kandage, Senal Liyanage, Charitha Rajapakse, Gayathri N. Silva
Publikováno v:
Bioremediation of Environmental Pollutants ISBN: 9783030861681
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0508a6214940218856fd4a39eb57aab2
https://doi.org/10.1007/978-3-030-86169-8_5
https://doi.org/10.1007/978-3-030-86169-8_5
Autor:
Dharshika Rajalingam, Shansa Pranami E. Jayaweera, Sacheela Prasadi Wanigasinghe Kanakanamge, Gayathri N. Silva
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
The proteasome is crucial for the degradation of intracellular proteins and plays an important role in mediating a number of cell survival and progression events by controlling the levels of key regulatory proteins such as cyclins and caspases in bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696011cca4cce45430eaf99d7365c115
https://pubmed.ncbi.nlm.nih.gov/34858819
https://pubmed.ncbi.nlm.nih.gov/34858819
Autor:
Gayathri N. Silva, Anita J. Zaitouna, Eli Olson, Sujatha Krishnakumar, Aviva Geretz, Brogan Yarzabek, Daniel S. Ramon, Rasmi Thomas, Malini Raghavan, Jie Geng
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8+ T cells, inducing immunity against infections and cancers. Quality control mediated by peptide loading complex (PLC) components is expected to ens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3251e44bc3cdaa84c5167f879d7b5d6
https://elifesciences.org/articles/34961
https://elifesciences.org/articles/34961
Autor:
Daniel S. Ramon, Sujatha Krishnakumar, Malini Raghavan, Brogan Yarzabek, Gayathri N. Silva, Aviva Geretz, Rasmi Thomas, Jie Geng, Eli Olson, Anita J. Zaitouna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d980a67f1dedeed81edc745d8ad35a4c
https://doi.org/10.7554/elife.34961.051
https://doi.org/10.7554/elife.34961.051
Autor:
Daniel Kern, Ashley M. Floyd, Nilesh Joshi, Gayathri N. Silva, Amanda N. Cruz, Shirin Fatma, Rachel M. Simari, Tamara L. Hendrickson, Frédéric Fischer, Pitak Chuawong
Publikováno v:
Journal of Biological Chemistry. 288:3816-3822
Many bacteria lack genes encoding asparaginyl- and/or glutaminyl-tRNA synthetase and consequently rely on an indirect path for the synthesis of both Asn-tRNAAsn and Gln-tRNAGln. In some bacteria such as Thermus thermophilus, efficient delivery of mis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a13a69a2a6ba796a35ecc09ca98ca7
https://doi.org/10.1074/jbc.m112.441394
https://doi.org/10.1074/jbc.m112.441394
Autor:
Brogan Yarzabek, Gayathri N. Silva, Daniel S. Ramon, Jie Geng, Sujatha Krishnakumar, Malini Raghavan, Anita J. Zaitouna
Publikováno v:
Human Immunology. 78:69
Aim Among HLA class I (HLA-I) molecules, HLA-B allotypes are the most polymorphic and have dominant influences upon disease outcomes. HLA-B allotypes are known to differ markedly in their intracellular folding and peptidome characteristics. The Aim o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f777eb5e7b73b29562af96de5d7d7f17
https://doi.org/10.1016/j.humimm.2017.06.082
https://doi.org/10.1016/j.humimm.2017.06.082