Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gayathri N Sekhar"'
Autor:
Lisa Sanderson, Marcelo da Silva, Gayathri N Sekhar, Rachel C Brown, Hollie Burrell-Saward, Mehmet Fidanboylu, Bo Liu, Lea Ann Dailey, Cécile A Dreiss, Chris Lorenz, Mark Christie, Shanta J Persaud, Vanessa Yardley, Simon L Croft, Margarita Valero, Sarah A Thomas
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)
BackgroundHuman African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system st
Externí odkaz:
https://doaj.org/article/09b1e0c2a621449a9fa1562f25edd5f8
Autor:
Gayathri N Sekhar, Ana R Georgian, Lisa Sanderson, Gema Vizcay-Barrena, Rachel C Brown, Paula Muresan, Roland A Fleck, Sarah A Thomas
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173474 (2017)
Pentamidine is an effective trypanocidal drug used against stage 1 Human African Trypanosomiasis (HAT). At the blood-brain barrier (BBB), it accumulates inside the endothelial cells but has limited entry into the brain. This study examined transporte
Externí odkaz:
https://doaj.org/article/28e9a686342e4da29a0188fb884b4905
Autor:
Sarah A. Thomas, Lea Ann Dailey, Marcelo A. da Silva, Lisa Sanderson, Shanta J. Persaud, Margarita Valero, Simon L. Croft, Mark R. Christie, Hollie Burrell-Saward, Mehmet Fidanboylu, Chris Lorenz, Bo Liu, Cécile A. Dreiss, Rachel C. Brown, Gayathri N. Sekhar, Vanessa Yardley
Publikováno v:
PLoS Neglected Tropical Diseases
Sanderson, L, Da Silva, M, Sekhar, G, Brown, R, Burrell-Saward, H, Fidanboylu, M, Liu, B, Dailey, L A, Dreiss, C, Lorenz, C, Christie, M, Persaud, S, Yardley, V, Croft, S, Valero, M & Thomas, S 2021, ' Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug ', PLoS Neglected Tropical Diseases, vol. 15, no. 4, e0009276 . https://doi.org/10.1371/journal.pntd.0009276
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)
Sanderson, L, Da Silva, M, Sekhar, G, Brown, R, Burrell-Saward, H, Fidanboylu, M, Liu, B, Dailey, L A, Dreiss, C, Lorenz, C, Christie, M, Persaud, S, Yardley, V, Croft, S, Valero, M & Thomas, S 2021, ' Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug ', PLoS Neglected Tropical Diseases, vol. 15, no. 4, e0009276 . https://doi.org/10.1371/journal.pntd.0009276
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)
Background Human African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system s
Autor:
Khondaker M. Rahman, Doaa B. Farag, Rachel Lo, Martin Broadstock, Huzefa Rupawala, Sarah A. Thomas, Sevda Tomova Boyanova, Alice L. Fleckney, Suzanne Reeves, Gayathri N. Sekhar, Hao Wang
Publikováno v:
Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-19 (2019)
Sekhar, G N, Fleckney, A L, Boyanova, S T, Rupawala, H J, Lo, R, Wang, H, Farag, D, Rahman, K M, Broadstock, M, Reeves, S & Thomas, S A 2019, ' Region-specific blood–brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease ', Fluids and Barriers of the CNS, vol. 16, no. 1, 38 . https://doi.org/10.1186/s12987-019-0158-1
Fluids and Barriers of the CNS
Sekhar, G N, Fleckney, A L, Boyanova, S T, Rupawala, H J, Lo, R, Wang, H, Farag, D, Rahman, K M, Broadstock, M, Reeves, S & Thomas, S A 2019, ' Region-specific blood–brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease ', Fluids and Barriers of the CNS, vol. 16, no. 1, 38 . https://doi.org/10.1186/s12987-019-0158-1
Fluids and Barriers of the CNS
Background Research into amisulpride use in Alzheimer’s disease (AD) implicates blood–brain barrier (BBB) dysfunction in antipsychotic sensitivity. Research into BBB transporters has been mainly directed towards the ABC superfamily, however, solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83da2df8c37fba523aecf82cc928c3b3
https://doi.org/10.1101/582387
https://doi.org/10.1101/582387
Publikováno v:
Neuropeptides. 65:132
Autor:
Gayathri N, Sekhar, Christopher P, Watson, Mehmet, Fidanboylu, Lisa, Sanderson, Sarah A, Thomas
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 71
Human African trypanosomiasis (HAT or sleeping sickness) is a potentially fatal disease caused by the parasite, Trypanosoma brucei sp. The parasites are transmitted by the bite of insect vectors belonging to the genus Glossina (tsetse flies) and disp
Autor:
Mehmet Fidanboylu, Gayathri N. Sekhar, Christopher P. Watson, Lisa Sanderson, Sarah A. Thomas
Human African trypanosomiasis (HAT or sleeping sickness) is a potentially fatal disease caused by the parasite, Trypanosoma brucei sp. The parasites are transmitted by the bite of insect vectors belonging to the genus Glossina (tsetse flies) and disp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee14fac9284c6e0526c60b97fcfb7db3
https://doi.org/10.1016/bs.apha.2014.06.003
https://doi.org/10.1016/bs.apha.2014.06.003