Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gayathri, Gulendran"'
Autor:
Sho Yoshimoto, Nicholas Chester, Ailian Xiong, Enrico Radaelli, Hong Wang, Marc Brillantes, Gayathri Gulendran, Patrick Glassman, Don L. Siegel, Nicola J. Mason
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTPD-1 checkpoint inhibitors have revolutionized the treatment of patients with different cancer histologies including melanoma, renal cell carcinoma, and non-small cell lung carcinoma. However, only a subset of patients show a dramatic clinica
Externí odkaz:
https://doaj.org/article/e2cc3ba3c4cc456f979a67ebfed7ed7f
Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4
Autor:
Vijay G. Bhoj, Lucy Li, Kalpana Parvathaneni, Zheng Zhang, Stephen Kacir, Dimitrios Arhontoulis, Kenneth Zhou, Bevin McGettigan-Croce, Selene Nunez-Cruz, Gayathri Gulendran, Alina C. Boesteanu, Laura Johnson, Michael D. Feldman, Enrico Radaelli, Keith Mansfield, MacLean Nasrallah, Rebecca S. Goydel, Haiyong Peng, Christoph Rader, Michael C. Milone, Don L. Siegel
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 387-398 (2021)
Metastatic medullary thyroid cancer (MTC) is a rare but often aggressive thyroid malignancy with a 5-year survival rate of less than 40% and few effective therapeutic options. Adoptive T cell immunotherapy using chimeric antigen receptor (CAR)-modifi
Externí odkaz:
https://doaj.org/article/21295495ac0b4d158ff8bf09829bb9f3
Autor:
Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Sangya Agarwal, Lucas Van Gorder, Charles C. Reed, Gayathri Gulendran, Stephanie Ramos, Kate E. Broderick, J Joseph Kim, Kenneth E. Ugen, Gary Kobinger, Don L. Siegel, David B. Weiner, Kar Muthumani
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 4, Pp 907-918 (2020)
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–B
Externí odkaz:
https://doaj.org/article/4c5462e0a3344f308a609dd19930347f
Autor:
Nicola J. Mason, Nicholas Chester, Ailian Xiong, Antonia Rotolo, Ying Wu, Sho Yoshimoto, Patrick Glassman, Gayathri Gulendran, Don L. Siegel
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The immune checkpoint inhibitor (ICI) ipilimumab has revolutionized the treatment of patients with different cancer histologies, including melanoma, renal cell carcinoma, and non-small cell lung carcinoma. However, only a subset of patients shows dra
Externí odkaz:
https://doaj.org/article/3d1a06698fe447c889e66b51ed9b5518
Autor:
Gayathri Gulendran, David B. Weiner, Charles C. Reed, Sagar B. Kudchodkar, Kanika Asija, Hyeree Choi, Karuppiah Muthumani, Lucas Van Gorder, Sangya Agarwal, Piyush Borole, Don L. Siegel, Emma L. Reuschel, J. Joseph Kim, Stephanie Ramos, Kenneth E. Ugen, Gary P. Kobinger, Kate E. Broderick
Publikováno v:
Human Vaccines & Immunotherapeutics
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–B
Autor:
Ailian Xiong, Patrick M. Glassman, Nicholas Chester, Don L. Siegel, Sho Yoshimoto, Ying Wu, Antonia Rotolo, Nicola J. Mason, Gayathri Gulendran
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The immune checkpoint inhibitor (ICI) ipilimumab has revolutionized the treatment of patients with different cancer histologies, including melanoma, renal cell carcinoma, and non-small cell lung carcinoma. However, only a subset of patients shows dra
Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4
Autor:
Selene Nunez-Cruz, Michael Feldman, Kenneth Zhou, Christoph Rader, Haiyong Peng, Stephen Kacir, Keith Mansfield, Alina C. Boesteanu, Zheng Zhang, Enrico Radaelli, MacLean Nasrallah, Bevin McGettigan-Croce, Rebecca S. Goydel, Vijay Bhoj, Don L. Siegel, Michael C. Milone, Kalpana Parvathaneni, Gayathri Gulendran, Dimitrios Arhontoulis, Lucy Z. Li, Laura A. Johnson
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 387-398 (2021)
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 387-398 (2021)
Metastatic medullary thyroid cancer (MTC) is a rare but often aggressive thyroid malignancy with a 5-year survival rate of less than 40% and few effective therapeutic options. Adoptive T cell immunotherapy using chimeric antigen receptor (CAR)-modifi
Autor:
Eric M. Ostertag, Stephen Kacir, Douglas B. Cines, X. Long Zheng, Gayathri Gulendran, Don L. Siegel, Michelle Thiboutot
Publikováno v:
Transfusion. 56:1763-1774
BACKGROUND Acquired thrombotic thrombocytopenia purpura (TTP) is a life-threatening illness caused by autoantibodies that decrease the activity of ADAMTS13, the von Willebrand factor–cleaving protease. Despite efficacy of plasma exchange, mortality
Autor:
X. Long Zheng, Michelle Thiboutot, Douglas B. Cines, Mortimer Poncz, Khalil Bdeir, David G. Motto, Lenka Yunk, Stephen Kacir, Eric M. Ostertag, Vincent Hayes, Don L. Siegel, Gayathri Gulendran
Publikováno v:
Transfusion. 56:1775-1785
BACKGROUND Acquired thrombotic thrombocytopenic purpura (TTP) is a potentially fatal disease in which ultralarge von Willebrand factor (UL-VWF) multimers accumulate as a result of autoantibody inhibition of the VWF protease, ADAMTS13. Current treatme
Autor:
Yoshimoto, Sho, Chester, Nicholas, Xiong, Ailian, Radaelli, Enrico, Wang, Hong, Brillantes, Marc, Gulendran, Gayathri, Glassman, Patrick, Siegel, Don L., Mason, Nicola J.
Publikováno v:
mAbs; Jan-Dec2023, Vol. 15 Issue 1, p1-14, 14p