Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gayani Fernando"'
Autor:
Ricardo A. García, PhD, Bruce R. Ito, PhD, John A. Lupisella, MSc, Nancy A. Carson, BSc, Mei-Yin Hsu, MSc, Gayani Fernando, MSc, Madeleine Heroux, PhD, Michel Bouvier, PhD, Elizabeth Dierks, PhD, Ellen K. Kick, PhD, David A. Gordon, PhD, Jian Chen, PhD, Gabe Mintier, BSc, Marilyn Carrier, PhD, Stéphane St-Onge, MSc, Himanshu Shah, MSc, Jordan Towne, BSc, Marcela Sotelo Bucardo, BSc, Xiuying Ma, PhD, Carol S. Ryan, BSc, Nicholas R. Wurtz, PhD, Jacek Ostrowski, PhD, Francisco J. Villarreal, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 905-920 (2019)
Summary: Dysregulated inflammation following myocardial infarction (MI) promotes left ventricular (LV) remodeling and loss of function. Targeting inflammation resolution by activating formyl peptide receptors (FPRs) may limit adverse remodeling and p
Externí odkaz:
https://doaj.org/article/87187fce26ae464386af76218484bf38
Autor:
Mark S Borja, Lei Zhao, Bradley Hammerson, Chongren Tang, Richard Yang, Nancy Carson, Gayani Fernando, Xiaoqin Liu, Madhu S Budamagunta, Jacques Genest, Gregory C Shearer, Franck Duclos, Michael N Oda
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71541 (2013)
High density lipoprotein (HDL) cholesterol levels are associated with decreased risk of cardiovascular disease, but not all HDL are functionally equivalent. A primary determinant of HDL functional status is the conformational adaptability of its main
Externí odkaz:
https://doaj.org/article/1e58836a5d004ecdb31766e8e2e6b96a
Publikováno v:
Built Environment Project and Asset Management, 2016, Vol. 6, Issue 3, pp. 317-331.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/BEPAM-08-2014-0041
CMH Lahore Medical College and Institute of Dentistry CMH Lahore Medical College and Institute of Dentistry The Aga Khan University CMH Lahore Medical College and Institute of Dentistry The Aga Khan University CMH Lahore Medical College and Institute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb93aadc7efc9b5a3e85fb4b54abbe1
Publikováno v:
Journal of Engineering, Design and Technology, 2014, Vol. 12, Issue 1, pp. 53-70.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/JEDT-04-2012-0018
Autor:
John Lupisella, Stéphane St-Onge, Marilyn Carrier, Erica M. Cook, Tao Wang, Chi Sum, Gayani Fernando, Kendra Apgar, Rongan Zhang, Nancy Carson, Bradley J. Snyder, Carol S. Ryan, Xiuying Ma, Elizabeth A. Dierks, Sean Little, Ellen K. Kick, Nicholas R. Wurtz, Michel Bouvier, Madeleine Héroux, Ricardo A. Garcia
Publikováno v:
ACS pharmacologytranslational science. 5(10)
Formyl peptide receptor 2 (FPR2) plays an integral role in the transition of macrophages from a pro-inflammatory program to one that is pro-resolving. FPR2-mediated stimulation of resolution post myocardial infarction has demonstrated efficacy in rod
Autor:
Stéphane St-Onge, Bruce R. Ito, John A. Lupisella, Madeleine Héroux, Ricardo Garcia, Marilyn Carrier, Mei-Yin Hsu, Carol S. Ryan, Michel Bouvier, Elizabeth A. Dierks, Nicholas R. Wurtz, Ellen K. Kick, Jian Chen, Nancy A. Carson, Gayani Fernando, Jordan Kelly Towne, Jacek Ostrowski, Francisco Villarreal, Himanshu Shah, Xiuying Ma, Marcela Sotelo Bucardo, Gabe Mintier, David A. Gordon
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 905-920 (2019)
Summary: Dysregulated inflammation following myocardial infarction (MI) promotes left ventricular (LV) remodeling and loss of function. Targeting inflammation resolution by activating formyl peptide receptors (FPRs) may limit adverse remodeling and p
Autor:
Claudia Generaux, Heather Finlay, Susan R. Arthur, Mei-Yin Hsu, Roy Haskell, Peter S. Gargalovic, Joelle M. Onorato, Michael Basso, Rongan Zhang, Kimberley A. Lentz, Anne Rose, Carrie Xu, Lei Zhao, Jeffrey S. Bostwick, Gayani Fernando, Ricardo Garcia, Xue-Qing Chen, James Hennan, Michael C. Myers, R. Michael Lawrence, Petia Shipkova, Samuel Hellings
Publikováno v:
Analytical Biochemistry. 568:41-50
Apelin, the endogenous ligand for the APJ receptor, has generated interest due to its beneficial effects on the cardiovascular system. Synthesized as a 77 amino acid preproprotein, apelin is post-translationally cleaved to a series of shorter peptide
Autor:
Moises Muratt Bustamante-Pozo, Rongan Zhang, Nancy L. Carson, Madeleine Héroux, Michel Bouvier, Jian Chen, David A. Gordon, Bruce R. Ito, Stéphane St.-Onge, Gayani Fernando, Marilyn Carrier, Francisco Villarreal, Zhaoqing Wang, Alejandra Garate-Carrillo, Carol S. Ryan, Jignesh Nagar, Jacek Ostrowski, John A. Lupisella, Ricardo Garcia, Shailesh Dudhgaonkar, Debra Search, Ellen K. Kick, Xiuying Ma, Ruth R. Wexler, Mei-Yin Hsu, Elizabeth A. Dierks, Nicholas R. Wurtz, John Allocco
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • MI leads to ischemic damage of myocardium and activation of inflammatory programs as part of the wound healing response. • Selective activation of FPR2 on macrophages potentiates key cellular activities that enab
Highlights • MI leads to ischemic damage of myocardium and activation of inflammatory programs as part of the wound healing response. • Selective activation of FPR2 on macrophages potentiates key cellular activities that enab
Autor:
Rongan Zhang, Gayani Fernando, Francisco Villarreal, Bruce R. Ito, Elizabeth A. Dierks, Nicholas R. Wurtz, Mei-Yin Hsu, Ricardo Garcia, John A. Lupisella, Y Kohno, Jacek Ostrowski, Carol S. Ryan, Nancy L. Carson, Zhaoqing Wang, Y Asahina
Publikováno v:
European Heart Journal. 40
Background/Introduction Dysregulated inflammation following myocardial infarction (MI) can lead to maladaptive infarct healing, myocardial damage and heart failure. Formyl peptide receptor 2 (FPR2) plays an important role in the ligand-dependent regu