PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia

Autor: Gawel, Justyna M., Shouksmith, Andrew E., Raouf, Yasir S., Nawar, Nabanita, Toutah, Krimo, Bukhari, Shazreh, Manaswiyoungkul, Pimyupa, Olaoye, Olasunkanmi O., Israelian, Johan, Radu, Tudor B., Cabral, Aaron D., Sina, Diana, Sedighi, Abootaleb, de Araujo, Elvin D., Gunning, Patrick T.

Publikováno v: In European Journal of Medicinal Chemistry 1 September 2020 201

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia

Autor: Toutah, Krimo, Nawar, Nabanita, Timonen, Sanna, Sorger, Helena, Raouf, Yasir S., Bukhari, Shazreh, von Jan, Jana, Ianevski, Aleksandr, Gawel, Justyna M., Olaoye, Olasunkanmi O., Geletu, Mulu, Abdeldayem, Ayah, Israelian, Johan, Radu, Tudor B., Sedighi, Abootaleb, Bhatti, Muzaffar N., Hassan, Muhammad Murtaza, Manaswiyoungkul, Pimyupa, Shouksmith, Andrew E., Neubauer, Heidi A., de Araujo, Elvin D., Aittokallio, Tero Antero, Krämer, Oliver H., Moriggl, Richard, Mustjoki, Satu, Herling, Marco, Gunning, Patrick T.

Publikováno v: Toutah, Krimo Nawar, Nabanita Timonen, Sanna Sorger, Helena Raouf, Yasir S. Bukhari, Shazreh von Jan, Jana Ianevski, Aleksandr Gawel, Justyna M. Olaoye, Olasunkanmi O. Geletu, Mulu Abdeldayem, Ayah Israelian, Johan Radu, Tudor B. Sedighi, Abootaleb Bhatti, Muzaffar N. Hassan, Muhammad Murtaza Manaswiyoungkul, Pimyupa Shouksmith, Andrew E. Neubauer, Heidi A. de Araujo, Elvin D. Aittokallio, Tero Antero Krämer, Oliver H. Moriggl, Richard Mustjoki, Satu Herling, Marco Gunning, Patrick T. . Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia. Jo
Jo

Externí odkaz: http://hdl.handle.net/10852/93204
https://www.duo.uio.no/bitstream/handle/10852/93204/1/acs.jmedchem.1c00420.pdf

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Selective disruption of mitochondrial thiol redox state in cells and in vivo

Autor: Booty, Lee M, Gawel, Justyna M, Cvetko, Filip, Caldwell, Stuart T, Hall, Andrew R, Mulvey, John F, James, Andrew M, Hinchy, Elizabeth C, Prime, Tracy A, Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P, Clatworthy, Menna R, Ferdinand, John R, Prag, Hiran A, Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C, Murphy, Michael P

Mitochondrial glutathione (GSH) and thioredoxin (Trx) systems function independently of the rest of the cell. While maintenance of mitochondrial thiol redox state is thought vital for cell survival, this was not testable due to the difficulty of mani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6611183cf2117977bcae5a2b48f7b87
https://eprints.gla.ac.uk/174223/1/174223.pdf