Hemin promotes platelet activation and plasma membrane disintegration regulated by the subtilisin-like proprotein convertase furin.

Autor: Schaale D; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Laspa Z; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Balmes A; Institute of Applied Physics, Eberhard Karls University of Tübingen, Tübingen, Germany., Sigle M; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Dicenta-Baunach V; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Hochuli R; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Fu X; Institute of Pharmaceutical Sciences, Department of Pharmaceutical and Medicinal Chemistry, Eberhard Karls University of Tübingen, Tübingen, Germany., Serafimov K; Institute of Pharmaceutical Sciences, Department of Pharmaceutical and Medicinal Chemistry, Eberhard Karls University of Tübingen, Tübingen, Germany., Castor T; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Harm T; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Müller KAL; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Rohlfing AK; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany., Laufer S; Institute of Pharmaceutical Sciences, Department of Pharmaceutical and Medicinal Chemistry, Eberhard Karls University of Tübingen, Tübingen, Germany., Schäffer TE; Institute of Applied Physics, Eberhard Karls University of Tübingen, Tübingen, Germany., Lämmerhofer M; Institute of Pharmaceutical Sciences, Department of Pharmaceutical and Medicinal Chemistry, Eberhard Karls University of Tübingen, Tübingen, Germany., Gawaz M; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Nov 15; Vol. 38 (21), pp. e70155.

C5 Variant rs10985126 is Associated with Mortality in Patients with Symptomatic Coronary Artery Disease

Autor: Henes JK, Groga-Bada P, Schaeffeler E, Winter S, Hack L, Zdanyte M, Mueller K, Droppa M, Stimpfle F, Gawaz M, Langer H, Schwab M, Geisler T, Rath D

Publikováno v: Pharmacogenomics and Personalized Medicine, Vol Volume 14, Pp 893-903 (2021)

Jessica Kristin Henes,1,* Patrick Groga-Bada,1,* Elke Schaeffeler,2,3 Stefan Winter,2,3 Luis Hack,1 Monika Zdanyte,1 Karin Mueller,1 Michal Droppa,1 Fabian Stimpfle,1 Meinrad Gawaz,1 Harald Langer,4 Matthias Schwab,2,3,5,6 Tobias Geisler,1 Do

Externí odkaz: https://doaj.org/article/728faf1aa7144f2eabf5dd2d7e360a88

Pulsed-field ablation is not inferior to thermal ablation regarding atrial remodeling in patients with paroxysmal atrial fibrillation.

Autor: Kranert M; Department of Cardiology and Angiology, University Hospital Tübingen, Tübingen, Germany., Lopez G; Department of Cardiology and Angiology, University Hospital Tübingen, Tübingen, Germany., Scheckenbach C; Department of Pediatric Cardiology, University Children's Hospital Tübingen, Tübingen, Germany., Schreieck J; Department of Cardiology and Angiology, University Hospital Tübingen, Tübingen, Germany., Gawaz M; Department of Cardiology and Angiology, University Hospital Tübingen, Tübingen, Germany., Heinzmann D; Department of Cardiology and Angiology, University Hospital Tübingen, Tübingen, Germany., Rath D; Department of Cardiology and Angiology, University Hospital Tübingen, Tübingen, Germany. Electronic address: dominik.rath@med.uni-tuebingen.de.

Publikováno v: Heart rhythm [Heart Rhythm] 2024 Dec; Vol. 21 (12), pp. 2598-2599. Date of Electronic Publication: 2024 Jun 21.

Flavopiridol restores granulopoiesis in experimental models of severe congenital neutropenia.

Autor: Nasri M; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Dannenmann B; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Doll L; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Findik B; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Bernhard F; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Kandabarau S; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Klimiankou M; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Gawaz M; Department of Cardiology and Angiology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Lengerke C; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Zeidler C; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany., Welte K; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany; Department of Pediatric Hematology, Oncology, and Bone Marrow Transplantation, Children's Hospital, University Hospital Tuebingen, 72076 Tuebingen, Germany., Skokowa J; Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, 72076 Tuebingen, Germany; Gene and RNA Therapy Center (GRTC), Tuebingen University, 72076 Tuebingen, Germany. Electronic address: julia.skokowa@med.uni-tuebingen.de.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Nov 22. Date of Electronic Publication: 2024 Nov 22.

Coronary artery disease detection using deep learning and ultrahigh-resolution photon-counting coronary CT angiography.

Autor: Brendel JM; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Walterspiel J; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Hagen F; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Kübler J; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Brendlin AS; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Afat S; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Paul JF; Institut Mutualiste Montsouris, Department of Radiology, Cardiac Imaging, 75014 Paris, France; Spimed-AI, 75014 Paris, France., Küstner T; Department of Radiology, Diagnostic and Interventional Radiology, Medical Image and Data Analysis (MIDAS.lab), University of Tübingen, 72076, Germany., Nikolaou K; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany., Gawaz M; Department of Internal Medicine III, Cardiology and Angiology, University of Tübingen, 72076, Germany., Greulich S; Department of Internal Medicine III, Cardiology and Angiology, University of Tübingen, 72076, Germany., Krumm P; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany. Electronic address: patrick.krumm@uni-tuebingen.de., Winkelmann MT; Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076, Germany.

Publikováno v: Diagnostic and interventional imaging [Diagn Interv Imaging] 2024 Oct 03. Date of Electronic Publication: 2024 Oct 03.