DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia

Autor: Georgiadis, Panagiotis, Gavriil, Marios, Rantakokko, Panu, Ladoukakis, Efthymios, Botsivali, Maria, Kelly, Rachel S., Bergdahl, Ingvar A., Kiviranta, Hannu, Vermeulen, Roel C.H., Spaeth, Florentin, Hebbels, Dennie G.A.J., Kleinjans, Jos C.S., de Kok, Theo M.C.M., Palli, Domenico, Vineis, Paolo, Kyrtopoulos, Soterios A.

Publikováno v: In Environment International May 2019 126:24-36

2-Hydroxyglutarate modulates histone methylation at specific loci and alters gene expression via Rph1 inhibition.

Autor: Gavriil M; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg., Proietto M; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg., Paczia N; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg., Ginolhac A; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg., Halder R; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg., Valceschini E; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg., Sauter T; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg., Linster CL; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg carole.linster@uni.lu., Sinkkonen L; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg lasse.sinkkonen@uni.lu.

Publikováno v: Life science alliance [Life Sci Alliance] 2023 Nov 27; Vol. 7 (2). Date of Electronic Publication: 2023 Nov 27 (Print Publication: 2024).