Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gavrielle M Price"'
Autor:
Daniel P. Zimmer, Courtney M. Shea, Jenny V. Tobin, Boris Tchernychev, Peter Germano, Kristie Sykes, Ali R. Banijamali, Sarah Jacobson, Sylvie G. Bernier, Renee Sarno, Andrew Carvalho, Yueh-tyng Chien, Regina Graul, Emmanuel S. Buys, Juli E. Jones, James D. Wakefield, Gavrielle M. Price, Jennifer G. Chickering, G. Todd Milne, Mark G. Currie, Jaime L. Masferrer
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologi
Externí odkaz:
https://doaj.org/article/e994be112c3a40db87031271143e9556
Autor:
Guang Liu, Jaime L. Masferrer, Gavrielle M Price, Renee Sarno, Mark G. Currie, Courtney Shea, Emmanuel S. Buys
Publikováno v:
American Journal of Physiology-Renal Physiology. 318:F148-F159
Reduced nitric oxide (NO) and a decrease in cGMP signaling mediated by soluble guanylate cyclase (sGC) has been linked to the development of several cardiorenal diseases. Stimulation of sGC is a potential means for enhancing cGMP production in condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abb78b68f3d2989f5d2c089135d41a3
https://doi.org/10.1152/ajprenal.00247.2019
https://doi.org/10.1152/ajprenal.00247.2019
Autor:
Shu Yan, Mark G. Currie, Gavrielle M Price, Juli E. Jones, Guang Liu, Daniel P. Zimmer, Courtney Shea, Jaime L. Masferrer, William Warren, Elisabeth Lonie, Albert T. Profy
Publikováno v:
American journal of physiology. Renal physiology. 319(4)
Praliciguat, a clinical-stage soluble guanylate cyclase (sGC) stimulator, increases cGMP via the nitric oxide-sGC pathway. Praliciguat has been shown to be renoprotective in rodent models of hypertensive nephropathy and renal fibrosis. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfd7a770ddd1a657423be5a37b7a160
https://pubmed.ncbi.nlm.nih.gov/32865013
https://pubmed.ncbi.nlm.nih.gov/32865013
Autor:
Sarah Jacobson, Jenny Tobin, Renee Sarno, Jaime L. Masferrer, Andrew Carvalho, Boris Tchernychev, Yueh-Tyng Chien, G. Todd Milne, Jennifer G. Chickering, Peter Germano, Ali R. Banijamali, Gavrielle M Price, Emmanuel S. Buys, James Wakefield, Regina Graul, Juli E. Jones, Courtney Shea, Sylvie G. Bernier, Daniel P. Zimmer, Kristie Sykes, Mark G. Currie
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235faf214a0dad4f1fdd0e1ad72b1cd8
https://pubmed.ncbi.nlm.nih.gov/32322204
https://pubmed.ncbi.nlm.nih.gov/32322204
Autor:
Gavrielle M. Price, Emily A. Margolis, Joe Tien, Brent J. Coisman, Rebecca L. Thompson, Keith H. K. Wong, Tyler Ryan
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:106-114
In vivo, tissues are drained of excess fluid and macromolecules by the lymphatic vascular system. How to engineer artificial lymphatics that can provide equivalent drainage in biomaterials remains an open question. The current study elucidates design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22039ad0e73f3b3c4857ad60eb92209d
https://doi.org/10.1002/jbm.a.36211
https://doi.org/10.1002/jbm.a.36211
Publikováno v:
Cellular and Molecular Bioengineering. 9:73-84
Proper vascularization remains critical to the clinical application of engineered tissues. To engineer microvessels in vitro, we and others have delivered endothelial cells through preformed channels into patterned extracellular matrix-based gels. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69ef2481dd1d5c3813d9a99aaec5eee
https://doi.org/10.1007/s12195-016-0429-8
https://doi.org/10.1007/s12195-016-0429-8
Autor:
Alexander D. Leung, Joe Tien, Gavrielle M. Price, James G. Truslow, Keith H. K. Wong, Chitrangada Acharya
Publikováno v:
Biomaterials. 31:6182-6189
This work examines how mechanical signals affect the barrier function and stability of engineered human microvessels in microfluidic type I collagen gels. Constructs that were exposed to chronic low flow displayed high permeabilities to bovine serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f05bb231ddd3b6888ecc4387dcd4cf6
https://doi.org/10.1016/j.biomaterials.2010.04.041
https://doi.org/10.1016/j.biomaterials.2010.04.041
Publikováno v:
Biomaterials. 30:4435-4443
This computational study analyzes how to design a drainage system for porous scaffolds so that the scaffolds can be vascularized and perfused without collapse of the vessel lumens. We postulate that vascular transmural pressure – the difference bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45028f1b3e0a22e97de9436f6d0a890a
https://doi.org/10.1016/j.biomaterials.2009.04.053
https://doi.org/10.1016/j.biomaterials.2009.04.053
Autor:
Gavrielle M, Price, Joe, Tien
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 671
This chapter describes a protocol for forming open endothelial tubes in vitro and quantifying their permeability to macromolecules. These tubes consist of confluent monolayers of human microvascular endothelial cells in perfused microfluidic collagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::445b162e8f5fb9dd5c0a5b7b834ac81b
https://pubmed.ncbi.nlm.nih.gov/20967637
https://pubmed.ncbi.nlm.nih.gov/20967637
Autor:
Joe Tien, Gavrielle M. Price
Publikováno v:
Methods in Molecular Biology ISBN: 9781934115954
This chapter describes a protocol for forming open endothelial tubes in vitro and quantifying their permeability to macromolecules. These tubes consist of confluent monolayers of human microvascular endothelial cells in perfused microfluidic collagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8d9933ecba3a8f675f1321a0b6835a
https://doi.org/10.1007/978-1-59745-551-0_17
https://doi.org/10.1007/978-1-59745-551-0_17
