Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Gavin Y Wang"'
Autor:
Desirée Bartolini, Yanzhong Wang, Jie Zhang, Daniela Giustarini, Ranieri Rossi, Gavin Y Wang, Pierangelo Torquato, Danyelle M Townsend, Kenneth D Tew, Francesco Galli
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0205626 (2019)
2,2'-diselenyldibenzoic acid (DSBA) is a chemical probe produced to explore the pharmacological properties of diphenyldiselenide-derived agents with seleno-hormetic activity undergoing preclinical development. The present study was designed to verify
Externí odkaz:
https://doaj.org/article/b7a553f8517848bfb18d42ceb2dd368c
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60065 (2013)
Resveratrol (RV) is a natural component of red wine and grapes that has been shown to be a potential chemopreventive and anticancer agent. However, the molecular mechanisms underlying RV's anticancer and chemopreventive effects are incompletely under
Externí odkaz:
https://doaj.org/article/f5bb68c66a0a4d718cdc18a7a0f8f74a
Publikováno v:
Biochemical and Biophysical Research Communications. 617:30-35
The accumulation of senescent cells in aged tissues has been implicated in a variety of age-related diseases, including cancer and neurodegenerative disorders. Recent studies have demonstrated a link between age-associated increase of senescent glial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba783d8974a9b0d78e857a447eba5e0e
https://doi.org/10.1016/j.bbrc.2022.05.090
https://doi.org/10.1016/j.bbrc.2022.05.090
Autor:
Gavin Y. Wang, Kenneth D. Tew, Stephen P. Ethier, Bradley A. Schulte, Shenghui Qin, Aimin Yang
Additional methods on drug screen, CSC sorting, real-time PCR, flow cytometric apoptosis assay and immunohistochemical (IHC) analysis are provided.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cb22e01a55a35f775d87350ffd7c8b
https://doi.org/10.1158/0008-5472.22416513
https://doi.org/10.1158/0008-5472.22416513
Autor:
Gavin Y. Wang, Kenneth D. Tew, Stephen P. Ethier, Bradley A. Schulte, Shenghui Qin, Aimin Yang
There is mounting evidence that cancer stem-like cells (CSC) are selectively enriched in residual tumors after anticancer therapies, which may account for tumor recurrence and metastasis by regenerating new tumors. Thus, there is a critical need to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7afa65abb7a957dbd464eb1b479a2c
https://doi.org/10.1158/0008-5472.c.6509574.v1
https://doi.org/10.1158/0008-5472.c.6509574.v1
Autor:
Kenneth D. Tew, Danyelle M. Townsend, Gavin Y. Wang, Annamarie C. Dalton, Ann-Marie Broome, Yu-Lin Jiang, Jennifer R. Bethard, Lauren E. Ball, Yefim Manevich, Zhiwei Ye, Jie Zhang, Leilei Zhang
Supplementary Figure S1. Effects of HO-1 knockdown in H460 cell lines and HO-1 over-expression in H596 cell lines. Supplementary Figure S2. Affinity Enrichment Mass Spectrometry. Supplementary Figure S3. ME-344 induced apoptosis in sensitive cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df95f93dbd8b4a935ec892fe6617a6f4
https://doi.org/10.1158/0008-5472.22422380.v1
https://doi.org/10.1158/0008-5472.22422380.v1
Autor:
Kenneth D. Tew, Danyelle M. Townsend, Gavin Y. Wang, Annamarie C. Dalton, Ann-Marie Broome, Yu-Lin Jiang, Jennifer R. Bethard, Lauren E. Ball, Yefim Manevich, Zhiwei Ye, Jie Zhang, Leilei Zhang
Antibodies. Primers. Click Chemistry and Affinity Enrichment Mass Spectrometry. Surface Plasmon Resonance - Biacore 3000 Kinetic Determinations. Co-Immunoprecipitation. Transfections with shRNA and plasmids. Plate colony formation assay. References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4af3189cf5be1b0176c1c02092dc19a
https://doi.org/10.1158/0008-5472.22422377.v1
https://doi.org/10.1158/0008-5472.22422377.v1
Autor:
Kenneth D. Tew, Danyelle M. Townsend, Gavin Y. Wang, Annamarie C. Dalton, Ann-Marie Broome, Yu-Lin Jiang, Jennifer R. Bethard, Lauren E. Ball, Yefim Manevich, Zhiwei Ye, Jie Zhang, Leilei Zhang
ME-344 is a second-generation isoflavone with unusual cytotoxic properties that is in clinical testing in cancer. To identify targets that contribute to its anticancer activity and therapeutic index, we used lung cancer cell lines that are naturally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d6592241410b1bfe0f4cd9def7ffcb
https://doi.org/10.1158/0008-5472.c.6511193
https://doi.org/10.1158/0008-5472.c.6511193
Autor:
Kenneth D. Tew, Danyelle M. Townsend, Gavin Y. Wang, Annamarie C. Dalton, Ann-Marie Broome, Yu-Lin Jiang, Jennifer R. Bethard, Lauren E. Ball, Yefim Manevich, Zhiwei Ye, Jie Zhang, Leilei Zhang
Supplementary Table S11. All Proteins Identified. Supplementary Table S12. The Protein Groups text file from MaxQuant was processed using Perseus. Common contaminants, reversed database hits, and proteins identified by modified peptides were removed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138cff6a711dbba5febe1c23a9e7c6be
https://doi.org/10.1158/0008-5472.22422374.v1
https://doi.org/10.1158/0008-5472.22422374.v1
Autor:
Gavin Y. Wang, Kenneth D. Tew, Stephen P. Ethier, Bradley A. Schulte, Shenghui Qin, Aimin Yang
The Supplementary Figures and Legends provide additional information on Flow Cytometry gating strategy for TNBC CSC sorting, the effects of C1572 on additional TNBC cells, the evidence that C1572 reversibly inhibits MYC, comparing the effectiveness o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0687c49bc7937009df037d4fc6d3ff70
https://doi.org/10.1158/0008-5472.22416516.v1
https://doi.org/10.1158/0008-5472.22416516.v1