Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gavin T. Knight"'
Autor:
Gavin T Knight, Brady F Lundin, Nisha Iyer, Lydia MT Ashton, William A Sethares, Rebecca M Willett, Randolph Scott Ashton
Publikováno v:
eLife, Vol 7 (2018)
Human pluripotent stem cell (hPSC)-derived neural organoids display unprecedented emergent properties. Yet in contrast to the singular neuroepithelial tube from which the entire central nervous system (CNS) develops in vivo, current organoid protocol
Externí odkaz:
https://doaj.org/article/1fa2e3a854e64c92958b13c035acd8cd
Autor:
Ty Harkness, Gavin T. Knight, Kaivalya Molugu, Ryan Prestil, Krishanu Saha, Stephanie K. Seymour, Randolph S. Ashton, Nicole J. Piscopo, Jared Carlson-Stevermer
Publikováno v:
Biophys J
Reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) generates valuable resources for disease modeling, toxicology, cell therapy, and regenerative medicine. However, the reprogramming process can be stochastic and inefficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb678e8dbcd7b7f428853b2f3ceacdd4
https://europepmc.org/articles/PMC7203070/
https://europepmc.org/articles/PMC7203070/
Autor:
Gavin T. Knight, Randolph S. Ashton, Max R. Salick, Rachel A. Kruepke, Wendy C. Crone, Brett N. Napiwocki
Publikováno v:
Journal of Applied Physics. 127:194701
Recent advances in stem cell biology have allowed researchers to efficiently produce large numbers of cardiomyocytes from various pluripotent cell sources. Unfortunately, these cells exhibit properties that are characteristics of immature cardiomyocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb30f1417a4d3fa84a80d763d75590b6
https://doi.org/10.1063/1.5129347
https://doi.org/10.1063/1.5129347
Autor:
Randolph S. Ashton, Brady F Lundin, Lydia Mt Ashton, Gavin T. Knight, Nisha Iyer, Rebecca Willett, William A. Sethares
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Human pluripotent stem cell (hPSC)-derived neural organoids display unprecedented emergent properties. Yet in contrast to the singular neuroepithelial tube from which the entire central nervous system (CNS) develops in vivo, current organoid protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752f433c9cabad51b651c1061ea63fc5
https://elifesciences.org/articles/37549
https://elifesciences.org/articles/37549
Autor:
Willett Rl, Nisha Iyer, Randolph S. Ashton, Lydia Mt Ashton, Brady F Lundin, Gavin T. Knight, William A. Sethares
Human pluripotent stem cell (hPSC)-derived neural organoids have revolutionized in vitro modelling of human neurological disorders. Cell-intrinsic morphogenesis processes displayed within these tissues could serve as the basis for ex vivo manufacture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06abc6118bac177b931c42ffd94f7c55
Publikováno v:
Chemical Communications. 51:5238-5241
We describe a modular culture platform that enables spatiotemporal control of the morphology of 2D neural tissues derived from human pluripotent stem cells (hPSCs) by simply adding clickable peptides to the media. It should be widely applicable for e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ad2d28317c920dc40d7acee3cbf0fb
https://doi.org/10.1039/c4cc08665a
https://doi.org/10.1039/c4cc08665a
Autor:
Feng Hou, Lin Yuan, Gavin T. Knight, E. B. Frankel, Randy Schekman, Michael G. Hanna, Randolph S. Ashton, Adam Johnson, Yufeng Tong, James J. Moresco, Samuel Block, Anjon Audhya, John R. Yates
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 37
The conserved coat protein complex II (COPII) mediates the initial steps of secretory protein trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two layers to generate cargo-laden transport carriers that ultimately fuse wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77be1486e633d69d9f5256cd6a4ff30
https://pubmed.ncbi.nlm.nih.gov/28973870
https://pubmed.ncbi.nlm.nih.gov/28973870
Autor:
Ty Harkness, Stephanie K. Seymour, Randolph S. Ashton, Gavin T. Knight, Ryan Prestil, Krishanu Saha, Jared Carlson-Stevermer
Reprogramming of human somatic cells to induce pluripotent stem cells (iPSCs) generates valuable precursors for disease modeling and regenerative medicine. However, the reprogramming process can be inefficient and noisy, creating many partially repro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7200b30f19ce1ee37cdc437d9cc2330a
Polyamidoamine (PAMAM) dendrimer was conjugated with both carboxymethyl-β-cyclodextrin (βCD) and poly(ethylene glycol) (PEG). Cyclic RGD peptide, used as a tumor targeting ligand, was then selectively conjugated onto the distal ends of the PEG arms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95711950fb03ecc48a67a0d1f562470f
https://europepmc.org/articles/PMC4336634/
https://europepmc.org/articles/PMC4336634/