Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Gavin P. Vinson"'
Autor:
Hilary R. Glover, Stewart Barker, Sylvanie D. M. Malouitre, John R. Puddefoot, Gavin P. Vinson
Publikováno v:
Pharmaceuticals, Vol 3, Iss 11, Pp 3417-3434 (2010)
Several lines of evidence attest to the existence of alternative ligand binding sites on the oestrogen receptor (ER), including non-competitive inhibition by trilostane or tamoxifen. It is possible that the inhibitory action of conventional oestrogen
Externí odkaz:
https://doaj.org/article/ab678c46693848a89df00f280455cd57
Autor:
Isabel M.P.L.V.O. Ferreira, Liliana Carvalho, Madalena Costa, Celso E. Gomez-Sanchez, Sofia S Pereira, Gavin P. Vinson, Mariana P. Monteiro, Armindo Melo, Duarte Pignatelli
Publikováno v:
Biomedicines
Volume 9
Issue 4
Biomedicines, Vol 9, Iss 441, p 441 (2021)
Volume 9
Issue 4
Biomedicines, Vol 9, Iss 441, p 441 (2021)
Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act by blocking aldosterone action. The aim of this study was to evaluate whether the MRAs spironolactone and eplerenone influence adrenal cortical physiology a
Autor:
John P. Coghlan, Gavin P. Vinson
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 65:381-404
James F. Tait FRS, with his wife Sylvia A. S. Tait FRS, made an indelible contribution to life science and medicine with the isolation and characterization of aldosterone, the most potent mineralocorticoid hormone produced by the mammalian adrenal co
Autor:
Gavin P. Vinson, Liliana Carvalho, Madalena Costa, Mariana P. Monteiro, Angela Moreira, Sofia S Pereira, Duarte Pignatelli
Publikováno v:
Endocrine Abstracts.
Autor:
Gavin P. Vinson, Caroline H. Brennan
Publikováno v:
Endocrine Connections
Substantial evidence shows that the hypophyseal–pituitary–adrenal (HPA) axis and corticosteroids are involved in the process of addiction to a variety of agents, and the adrenal cortex has a key role. In general, plasma concentrations of cortisol
Autor:
Gavin P. Vinson
Publikováno v:
Frontiers in Neuroscience
The standard model of adrenocortical zonation holds that the three main zones, glomerulosa, fasciculata, and reticularis each have a distinct function, producing mineralocorticoids (in fact just aldosterone), glucocorticoids, and androgens respective
Publikováno v:
Baiamonte, M, Parker, M, Vinson, G & Brennan, C H 2016, ' Sustained effects of developmental exposure to ethanol on zebrafish anxiety-like behaviour ', PLoS One . https://doi.org/10.1371/journal.pone.0148425
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0148425 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0148425 (2016)
In zebrafish developmentally exposed to ambient ethanol (20mM-50mM) 1-9 days post fertilization (dpf), the cortisol response to stress has been shown to be significantly attenuated in larvae, juveniles and 6 month old adults. These data are somewhat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9e3f41db827cd3f9397c7a9a008d9ffc
https://researchportal.port.ac.uk/ws/files/3392308/Baiamonte_et_al_revised_chb_1_12_15.docx
https://researchportal.port.ac.uk/ws/files/3392308/Baiamonte_et_al_revised_chb_1_12_15.docx
Autor:
Gavin P. Vinson
Publikováno v:
Oncotarget
Drugs that target the Renin-Angiotensin System (RAS) have recently come into focus for their potential utility as cancer treatments. The use of Angiotensin Receptor Blockers (ARBs) and Angiotensin-Converting Enzyme (ACE) Inhibitors (ACEIs) to manage
Publikováno v:
Endocrine-Related Cancer. 19:R1-R19
Much evidence now suggests that angiotensin II has roles in normal functions of the breast that may be altered or attenuated in cancer. Both angiotensin type 1 (AT1) and type 2 (AT2) receptors are present particularly in the secretory epithelium. Add
Autor:
Gavin P. Vinson
Publikováno v:
Journal of Endocrinology. 211:3-16
Over the 70 or so years since their discovery, there has been continuous interest and activity in the field of corticosteroid functions. However, despite major advances in the characterisation of receptors and coregulators, in some ways we still lack