Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Gavin J, Miller"'
Publikováno v:
ACS Omega, Vol 9, Iss 29, Pp 31703-31713 (2024)
Externí odkaz:
https://doaj.org/article/936cefde1f6d4d0eabd4f3f5c645bf46
Autor:
Hannah S. Wootton, Gavin J. Miller
Publikováno v:
Molbank, Vol 2024, Iss 3, p M1847 (2024)
Methyl and benzyl (ethyl 3,4-di-O-benzyl-2-O-benzoyl-1-thio-β-D-glucopyranosyl)uronate were synthesised from a protected thioglycoside in three steps. A regioselective ring opening of the benzylidene acetal with BH3.THF generated C6-OH material, whi
Externí odkaz:
https://doaj.org/article/c155d7cc4fa24c318a9711b8170434f5
Autor:
Sanaz Ahmadipour, Alice J. C. Wahart, Jonathan P. Dolan, Laura Beswick, Chris S. Hawes, Robert A. Field, Gavin J. Miller
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 1379-1384 (2022)
Sufferers of cystic fibrosis are at significant risk of contracting chronic bacterial lung infections. The dominant pathogen in these cases is mucoid Pseudomonas aeruginosa. Such infections are characterised by overproduction of the exopolysaccharide
Externí odkaz:
https://doaj.org/article/897c1b0ffb0340a0afbd2a9a48f64934
Autor:
Eleni Dimitriou, Gavin J. Miller
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1527-1532 (2021)
Alginate is a biocompatible and industrially relevant polysaccharide that derives many of its important properties from the charged carboxylate groups within its polyuronic acid backbone. The design and inclusion of isosteric replacements for these c
Externí odkaz:
https://doaj.org/article/5e6f2492cf3a49c9ab27dfc1e8124f2a
Autor:
Courtney J Mycroft-West, Anthony J Devlin, Lynsay C Cooper, Patricia Procter, Gavin J Miller, David G Fernig, Marco Guerrini, Scott E Guimond, Marcelo A Lima, Edwin A Yates, Mark Andrew Skidmore
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 8, Pp 1546-1553 (2020)
The pharmaceutical and anticoagulant agent heparin, a member of the glycosaminoglycan family of carbohydrates, has previously been identified as a potent inhibitor of a key Alzheimer’s disease drug target, the primary neuronal β-secretase, β-site
Externí odkaz:
https://doaj.org/article/d30637bf9c56424598842f9e806a405d
Publikováno v:
Royal Society Open Science, Vol 9, Iss 1 (2022)
Oxidation is one of the most important processes used by the chemical industry. However, many of the methods that are used pose significant sustainability and environmental issues. Biocatalytic oxidation offers an alternative to these methods, with a
Externí odkaz:
https://doaj.org/article/faa72b4248be44ddb610d59defaa7f67
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100063- (2021)
The impact of fungal infections on humans is a serious public health issue that has received much less attention than bacterial infection and treatment, despite ever-increasing incidence exacerbated by an increased incidence of immunocompromised indi
Externí odkaz:
https://doaj.org/article/fcc266c314564564b94466e9143f6517
Publikováno v:
JACS Au. 3:47-61
Autor:
Eleni Dimitriou, Gavin J. Miller
Publikováno v:
Molbank, Vol 2020, Iss 1, p M1111 (2020)
Methyl [S-phenyl 4-O-acetyl-2,3-di-O-benzyl-1-thio-α-d-mannopyranoside (R/S)S-oxide] uronate was synthesised from a thioglycoside mannosyl uronate donor in a 98% yield. By using one equivalent of meta-chloroperbenzoic acid (m-CPBA) as the sulphur ox
Externí odkaz:
https://doaj.org/article/73a1d4890ad147b88341e5614779748f
Autor:
Maria C.Z. Meneghetti, Lucy Naughton, Conor O’Shea, Dindet S.-E. Koffi Teki, Vincent Chagnault, Helena B. Nader, Timothy R. Rudd, Edwin A. Yates, José Kovensky, Gavin J. Miller, Marcelo A. Lima
Publikováno v:
ACS Omega. 7:24461-24467
Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is ubiquitously distributed throughout the animal kingdom and represents a key regulator of biological processes and a largely untapped res