Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gavin Hanson"'
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228730 (2020)
Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in the cell and is a major control point for modulating gene expression. In yeast and other model organisms, codon identity is a powerful determinant of transcript
Externí odkaz:
https://doaj.org/article/9b0d297e33144ab3b3aae497350dd684
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 2, p e0228730 (2020)
PLoS ONE, Vol 15, Iss 2, p e0228730 (2020)
Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in the cell and is a major control point for modulating gene expression. In yeast and other model organisms, codon identity is a powerful determinant of transcript
Autor:
Daniel Arango, Shalini Oberdoerffer, Ashrut Narula, Thomas J. Sweet, James Ellis, Megan E. Forrest, Gavin Hanson, Jeff Coller, Olivia S. Rissland
mRNA degradation is a critical, yet poorly understood, aspect of gene expression. Previous studies demonstrate that codon content acts as a major determinant of mRNA stability in model organisms. In humans, the importance of open reading frame (ORF)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8380c5fbce93ef2db7dd4948b87984a
https://doi.org/10.1101/488676
https://doi.org/10.1101/488676
Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in eukaryotic cells. Previous work by us and others has shown that codon identity exerts a powerful influence on mRNA stability. InSaccharomyces cerevisiae, studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0669dc3df0f5a4d6d032776d961fa42
https://doi.org/10.1101/300467
https://doi.org/10.1101/300467
Autor:
Gavin Hanson, Jeff Coller
Publikováno v:
Nature reviews. Molecular cell biology. 19(1)
The advent of ribosome profiling and other tools to probe mRNA translation has revealed that codon bias - the uneven use of synonymous codons in the transcriptome - serves as a secondary genetic code: a code that guides the efficiency of protein prod
Autor:
Jeff Coller, Najwa Alhusaini, Thomas Zengeya, Jordan L. Meier, Wilson R. Sinclair, Thorkell Andresson, Stephen D. Fox, Mariana D. Mandler, Allissa Dillman, Masaki Hosogane, Thomas J. Sweet, David Sturgill, Daniel Arango, Kyster K. Nanan, Shalini Oberdoerffer, Gavin Hanson
Publikováno v:
Cell. 175:1872-1886.e24
Summary Generation of the "epitranscriptome" through post-transcriptional ribonucleoside modification embeds a layer of regulatory complexity into RNA structure and function. Here, we describe N4-acetylcytidine (ac4C) as an mRNA modification that is
Autor:
In-Young Choi, Christopher H. Ramey, William Brooks, Laura E. Martin, Phil Lee, Evangelia G. Chrysikou, Gavin Hanson
Publikováno v:
Brain Stimulation, Vol 10, Iss 4, Pp e53-e54 (2017)
Autor:
Forrest, Megan E.1,2 (AUTHOR), Pinkard, Otis1,2 (AUTHOR), Martin, Sophie1 (AUTHOR), Sweet, Thomas J.1 (AUTHOR), Hanson, Gavin1 (AUTHOR), Coller, Jeff1,2 (AUTHOR) jmc71@case.edu
Publikováno v:
PLoS ONE. 2/13/2020, Vol. 15 Issue 2, p1-33. 33p.
Autor:
Zeidan, Quira1, Zhang, Fan1, Zhang, Hongen1, Hinnebusch, Alan G.1, He, Feng2, Jacobson, Allan2
Publikováno v:
PLoS Genetics. 12/7/2018, Vol. 14 Issue 12, p1-42. 42p.