Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gavin D. Richardson"'
Autor:
Maria Camacho-Encina, Laura K. Booth, Rachael E. Redgrave, Omowumi Folaranmi, Ioakim Spyridopoulos, Gavin D. Richardson
Publikováno v:
Cells, Vol 13, Iss 4, p 353 (2024)
Cardiovascular diseases (CVDs), a group of disorders affecting the heart or blood vessels, are the primary cause of death worldwide, with an immense impact on patient quality of life and disability. According to the World Health Organization, CVD tak
Externí odkaz:
https://doaj.org/article/9f2738edc5dc4a2094a9568a90c44cec
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Cancer continues to place a heavy burden on healthcare systems around the world. Although cancer survivorship continues to improve, cardiotoxicity leading to cardiomyopathy and heart failure as a consequence of cancer therapy is rising, and yesterday
Externí odkaz:
https://doaj.org/article/6dec66949d2e44a1be92fcf8d44d1f9f
Autor:
Kristina Tomkova, Marius Roman, Adewale S Adebayo, Sophia Sheikh, Syabira Yusoff, Melanie Gulston, Lathishia Joel-David, Florence Y Lai, Antonio Murgia, Bryony Eagle-Hemming, Hardeep Aujla, Gavin D Richardson, Julian L Griffin, Gavin J Murphy, Marcin J Woźniak
BackgroundTwo-thirds of people over 65 have two or more underlying chronic conditions. Patients with multimorbidities are likely to classify as frail and have worse outcomes after cardiac surgery. We hypothesized that metabolite and transcript profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3f1e0287674af0152207076f5a4748
https://doi.org/10.1101/2023.02.22.23286318
https://doi.org/10.1101/2023.02.22.23286318
Autor:
Laura K. Booth, Rachael E. Redgrave, Simon Tual-Chalot, Ioakim Spyridopoulos, Helen M. Phillips, Gavin D. Richardson
Publikováno v:
Subcellular Biochemistry ISBN: 9783031265754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44608132f5f83b8dfbcd85ab0bd2b219
https://doi.org/10.1007/978-3-031-26576-1_4
https://doi.org/10.1007/978-3-031-26576-1_4
Autor:
Haaris Ahmed, Ioakim Spyridopoulos, Syeda E R Adil, Konstantinos Stellos, Luke Spray, Jose Coelho-Lima, Georgios Georgiopoulos, Kimon Stamatelopoulos, Javed Ahmed, Fareen Ahmed, Alan Bagnall, Constantinos Bakogiannis, Kateryna Sopova, David Gaskin, Gavin D. Richardson
Publikováno v:
Heart. 107:1881-1888
Background and aimAlthough the diagnostic usefulness of high-sensitivity cardiac troponin T (hs-cTnT) is well established in ST-segment elevation myocardial infarction (STEMI), its prognostic relevance in risk stratification of patients with STEMI re
Publikováno v:
Cardiovascular Drugs and Therapy
Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular disease being the leading cause of death in 40% of individuals over 65 years old. Ageing is associated with both an increased prevalence of cardiovascular disea
Autor:
João V de Souza, Gavin D. Richardson, Fehmi M Benli, Danlin Liu, Ioakim Spyridopoulos, Agnieszka K. Bronowska, Catherine Park
Publikováno v:
Clinical Science. 134:2243-2262
In the elderly population, pathological inflammation has been associated with ageing-associated diseases. The term ‘inflammageing’, which was used for the first time by Franceschi and co-workers in 2000, is associated with the chronic, low-grade,
Publikováno v:
Mechanisms of Ageing and Development
Highlights • Studies have demonstrated that senescence contributes to the pathophysiology of several age-related cardiovascular diseases. • Senolytics eliminate senescent cells in cardiovascular tissues and prevent or reverse disease progression.
Autor:
Ioakim Spyridopoulos, Gavin D. Richardson, Judith Haendeler, Jedrzej Hoffmann, Joachim Altschmied, Vicente Andrés
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(3)
Shortened telomeres have been linked to numerous chronic diseases, most importantly coronary artery disease, but the underlying mechanisms remain ill defined. Loss-of-function mutations and deletions in telomerase both accelerate telomere shortening
Autor:
Stephen Boag, Suzanne Cormack, Gavin D. Richardson, Luke Spray, A Mohammad, Ioakim Spyridopoulos, Catherine Park, Konstantinos Stellos, Pedram Panahi, Karim Bennaceur, Helen M. Arthur
Publikováno v:
European Heart Journal. 41
Background Patients with latent cytomegalovirus (CMV) infection have higher rates of adverse cardiovascular outcomes, but the reasons for this remain elusive. CMV-induced changes to T-lymphocyte populations, with a proliferation of CMV-specific, CX3C