Výsledky vyhledávání - "Gavin B Chapman"

Utility of interval kidney biopsy in ANCA-associated vasculitis

Autor: Tariq E. Farrah, Eve Miller-Hodges, David C. Kluth, Rashmi Lahiri, Gavin B Chapman, Christopher Bellamy, Dan Pugh, Robert W. Hunter, Neeraj Dhaun, Fiona A Chapman

Publikováno v: Chapman, G B, Farrah, T, Chapman, F, Pugh, D, Bellamy, C O C, Lahiri, R, Miller-Hodges, E, Kluth, D C, Hunter, R W & Dhaun, N 2021, ' Utility of interval kidney biopsy in ANCA-associated vasculitis ', Rheumatology . https://doi.org/10.1093/rheumatology/keab695

Objectives ANCA-associated vasculitis (AAV) is a rare autoimmune disorder that commonly involves the kidney. Early identification of kidney involvement, assessing treatment-response and predicting outcome are important clinical challenges. Here, we a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1293e3fb7652c24afcd5c71bd9daf2
https://hdl.handle.net/20.500.11820/b72fe996-1409-4489-ab32-3c18eae8c93f

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Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome

Autor: David A, Dorward, Christopher D, Lucas, Mary K, Doherty, Gavin B, Chapman, Emma J, Scholefield, Andrew, Conway Morris, Jennifer M, Felton, Tiina, Kipari, Duncan C, Humphries, Calum T, Robb, A John, Simpson, Phillip D, Whitfield, Christopher, Haslett, Kevin, Dhaliwal, Adriano G, Rossi

Publikováno v: Thorax

Background Acute respiratory distress syndrome (ARDS) is an often fatal neutrophil-dominant lung disease. Although influenced by multiple proinflammatory mediators, identification of suitable therapeutic candidates remains elusive. We aimed to deline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a5de530743902be77e1f28d66b212249
https://pubmed.ncbi.nlm.nih.gov/28469031

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Non-small-cell lung carcinoma (not otherwise specified) rates are not influenced solely by pathologists’ decisions on the use of immunohistochemistry

Autor: David A Dorward, Gavin B Chapman, Christopher D. Lucas, William Wallace

Publikováno v: Chapman, G B, Dorward, D, Lucas, C & Wallace, W 2017, ' Non-small cell lung carcinoma (not otherwise specified) rates are not solely influenced by pathologists’ decisions on the use of immunohistochemistry. ', Histopathology, vol. 70, no. 3 . https://doi.org/10.1111/his.13074

With increasing focus on the molecular classification of non-small cell lung cancers (NSCLC) to guide therapeutic decisions the correct application of appropriate diagnostic tools is paramount. In small biopsy and cytology specimens the majority can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba834d5fcce264adb920d45310ab749
https://doi.org/10.1111/his.13074

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Interaction of mitochondrial formylated peptides with formyl peptide receptor 1 in the pathogenesis of acute lung injury

Autor: Jennifer M Felton, Chris Lucas, David A. Dorward, Adriano G. Rossi, Mary K. Doherty, Emma Scholefield, Gavin B Chapman, Andrew Conway-Morris, Kevin Dhaliwal, Tiina Kipari, Calum T. Robb, Philip D. Whitfield, Christopher Haslett

Publikováno v: The Lancet. 387:S38

Background Mortality in acute respiratory distress syndrome remains high with no effective pharmacological therapies. The syndrome is characterised by dysregulated neutrophilic inflammation and tissue damage, which leads to the release of various fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a8f836c42c9890311f8376447c13e34
https://doi.org/10.1016/s0140-6736(16)00425-6

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The Role of Formylated Peptides and Formyl Peptide Receptor 1 in Governing Neutrophil Function during Acute Inflammation

Autor: Kevin Dhaliwal, Gavin B Chapman, Adriano G. Rossi, Christopher Haslett, Christopher D. Lucas, David A. Dorward

Publikováno v: The American Journal of Pathology. (5):1172-1184

Neutrophil migration to sites of inflammation and the subsequent execution of multiple functions are designed to contain and kill invading pathogens. These highly regulated and orchestrated processes are controlled by interactions between numerous re

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